Germ Cell Tumours
Imaging of testicular germ cell tumours.
... Testicular germ cell tumours (GCT) are an increasingly common group of tumours, particularly in young ...these tumours is computed tomography (CT) but plain film radiography, ultrasound ...
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Is there still a place for retroperitoneal lymph node dissection in clinical stage 1 nonseminomatous testicular germ-cell tumours? A retrospective clinical study
... testicular germ cell tumours (GCTs) in Europe when the European Germ Cell Cancer Consensus Group released their recommendations in ...
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Investigation of the molecular basis of cisplatin sensitivity in testicular germ cell tumours
... testicular germ cell tumours was approximately 50% and the cure rate was 5-10% with standard chemotherapy consisting of dactinomycin, alone or in combination with methotrexate and chlorambucil ...
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DICER1 RNase IIIb domain mutations are infrequent in testicular germ cell tumours
... Testicular germ cell tumours (TGCTs), also referred to as type II TGCTs, are the most common cancer affect- ing adolescent and young men, and are typically diag- nosed around the age of ...immature ...
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The Administration of the Irinotecan with Oxaliplatin, Actinomycin and Methotrexate may not be Feasible for Relapsed Germ Cell Tumours with Poor Prognosis.
... The treatment of germ cell tumours is considered to be one of the major successes in the arena of cytotoxic chemotherapy. Even in patients who relapse after first- line therapy, a durable remission ...
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Consolidative high dose chemotherapy after conventional dose chemotherapy as first salvage treatment for male patients with metastatic germ cell tumours
... The IPFSG deserves much credit for the difficult task of devel- oping a prognostic classification system which has been des- perately needed for men with metastatic germ cell tumours receiving first ...
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Classification, epidemiology and therapies for testicular germ cell tumours
... Testicular Germ Cell tumours (TGCTs) account for between 1% and ...urological tumours in general, with 3-10 new cases occurring per 100,000 males/per year in Western society (La Vecchia et ...
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Study of Clinico Pathological Significance of C-Kit Expression in Germ Cell Tumours of Ovary with Special Reference to Dysgerminoma.
... This is to certify that this Dissertation entitled ―THE STUDY OF CLINICO PATHOLOGICAL SIGNIFICANCE OF C-KIT EXPRESSION IN GERM CELL TUMOURS OF OVARY WITH SPECIAL REFERENCE TO DYSGERMINOMA‖ is the ...
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Clinical and genetic aspects of testicular germ cell tumours
... In this paper we review clinical and genetic aspects of testicular germ cell tumours (TGCTs). TGCT is the most common type of malignant disorder in men aged 15-40 years. Its incidence has increased ...
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Comparison of carboplatin versus cisplatin in the treatment of paediatric extracranial malignant germ cell tumours: A report of the Malignant Germ Cell International Consortium
... comparisons of cisplatin vs. carboplatin in adult men with non-seminomatous testicular germ cell tumors, which are summarized in Supplemental Table 4. 7-10 There are several explanations for the observed ...
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Germ line DICER1 mutations do not make a major contribution to the etiology of familial testicular germ cell tumours
... neoplasia-associated germ-line and somatic mutations in DICER1 indicates that mis-expression of miRNAs in cancer may result from defects in their ...testicular germ cell tumors, a single RNase IIIb ...
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Epidermal growth factor receptor and epididymis invasion as prognostic biomarkers in clinical stage I testicular germ cell tumours
... 56 tumours analysed showed positive immunoreactivity to EGFR (Table ...seminoma tumours showed membra- nous immunoreactivity exclusively in the parenchyma cells ...embryonal tumours showed immunore- ...
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The association between institution at orchiectomy and outcomes on active surveillance for clinical stage I germ cell tumours
... CUAJ ? May June 2016 ? Volume 10, Issues 5 6 ? 2016 Canadian Urological Association ORIGINAL RESEARCH 204 Cite as Can Urol Assoc J 2016;10(5 6) 204 9 http //dx doi org/10 5489/cuaj 3513 Abstract Intro[.] ...
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The present and future of serum diagnostic tests for testicular germ cell tumours.
... 2 human chorionic gonadotrophin (HCG) and lactate dehydrogenase (LDH) show some utility in the management of testicular malignant GCT. However, AFP and HCG display limited sensitivity and specificity, being indicative of ...
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Epigenetic features of testicular germ cell tumours in relation to epigenetic characteristics of foetal germ cells
... directly germ cells, seem to be affected (Mahood et al., 2005). The effect on germ cells thus seems to be secondary but nevertheless adversely affecting their perinatal ...
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Application of the International Germ Cell Consensus Classification to the Nova Scotia population of patients with germ cell tumours
... (International Germ Cell Consensus Classifica- tion) est un système de classification pronostique mondialement reconnu, basé sur les données cliniques et utilisé pour faciliter la prise en charge des ...
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Genetic changes in human testicular germ cell tumours
... Two probes, one on each chromosome arm, were used to search for allelic deletions on chromosome 7. The results are presented in table 3.21 and summarized in table 3.23. Twenty seven patients were informative for XIVIS31 ...
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The genomic landscape of testicular germ cell tumours: from susceptibility to treatment.
... also consistently been reported, albeit at a lower frequency of ~5-10%. Subsequent to the initial targeted and hypothesis-driven analyses of individual genes/gene sets in TGCTs through which KIT and KRAS mutations were ...
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Ovarian masses - CT imaging
... epithelial tumours, 28% of all solid ovarian tumors -Brenner tumor (bilateral), germ cell tumours, 22%- ovarian teratoma: non cystic type, sex cord stromal tumours: ovarian fibroma, ...
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Histomorphological analysis of testicular and paratesticular lesions - 4 year study from a tertiary centre in South India
... spindle cell neoplasm with hyalinisation and prominent collagen bands with many thin walled blood vessels which aroused a possibility of solitary fibrous ...paratesticular tumours were less compared to non ...
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