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germ line

Strife in the germ line

Strife in the germ line

... In1 I De\' BinI 37 25 3] (1993) 25 Strife in the germ line CHRIS F GRAHAM' Cancer Research Campaign Growth Factors, Oxford University, Oxford, United Kingdom ABSTRACT The formation of germ cells, thei[.] ...

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The germ line and somatic stem cell gene Cniwi in the jellyfish Podocoryne carnea

The germ line and somatic stem cell gene Cniwi in the jellyfish Podocoryne carnea

... animals germ line cells are set apart from somatic development in the early ...and germ line cells is not established and germ stem cells arise de novo from somatic cells either at the ...

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Targeted mutagenesis: analysis of phenotype without germ line transmission

Targeted mutagenesis: analysis of phenotype without germ line transmission

... When ES cells are combined with tetraploid mouse embryos, fetuses and, in the best case scenario, viable offspring can be generated in which all tissues are ES derived (6, 7). This situa- tion is brought about by the ...

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Localization of mitochondrial large rRNA in germinal granules and the consequent segregation of germ line

Localization of mitochondrial large rRNA in germinal granules and the consequent segregation of germ line

... Int J Dev BinI 38 193 199 (1994) 193 Rrview Localization of mitochondrial large rRNA in germinal granules and the consequent segregation of germ line SATORU KOBAYASHI', REIKO AMIKURA and MASUKICHI OKA[.] ...

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Differential Reactivity of Germ Line Allelic Variants of a Broadly Neutralizing HIV-1 Antibody to a gp41 Fusion Intermediate Conformation

Differential Reactivity of Germ Line Allelic Variants of a Broadly Neutralizing HIV-1 Antibody to a gp41 Fusion Intermediate Conformation

... germ line allelic variants are capable of binding not only to the linear nominal 2F5 epitope but also to a gp41 conformation that mimics the fusion intermediate state, thus implying that the hu- man B cell ...

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glp-3 Is Required for Mitosis and Meiosis in the Caenorhabditis elegans Germ Line

glp-3 Is Required for Mitosis and Meiosis in the Caenorhabditis elegans Germ Line

... Since glp3 mutants fail to progress in either mitosis or meiosis in the germ line, glp3 may be required for both types of cell cycle. Alternatively, the lack of meiosis in glp3[r] ...

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Mouse germ line mutations due to retrotransposon insertions

Mouse germ line mutations due to retrotransposon insertions

... mouse germ line mutations caused by inser- tions of ...the germ line insertions occur in gene introns and disrupt transcript processing, notably splicing and polyadenylation (Table 1) ...

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A global disorder of imprinting in the human female germ line

A global disorder of imprinting in the human female germ line

... The contrasting behaviour of H19 and GNAS1-NESP55 in the BiCHM is noteworthy. Although both DMRs are normally pater- nally methylated, for H19 this is primary, and therefore unaffected by an oocyte defect. At NESP55, ...

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Generation of germ line chimera zebrafish using primordial germ cells isolated from cultured blastomeres and cryopreserved embryoids

Generation of germ line chimera zebrafish using primordial germ cells isolated from cultured blastomeres and cryopreserved embryoids

... whose germ-line cells were replaced with cryopreserved/thawed PGCs showed natural mating behavior with normal females and pro- duced ...of germ-line chimeras by transplantation of ...

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Epigenetic reprogramming of the genome  from the germ line to the embryo and back again

Epigenetic reprogramming of the genome from the germ line to the embryo and back again

... the germ line where much of the focus of research needs to be ...the germ cell lineage itself, including how the germ cells are established in the absence of germ line ...

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Germ-line transmission of trisomy 21: Data from 80 families suggest an implication of grandmaternal age and a high frequency of female-specific trisomy rescue

Germ-line transmission of trisomy 21: Data from 80 families suggest an implication of grandmaternal age and a high frequency of female-specific trisomy rescue

... fluid specimen from a normal male pregnancy (Addi- tional File 1: Table S1, case 53). In six cases, GM was uncovered by DNA analysis. Maternal origin of T21 in the affected offspring was proven in 15 families. In the ...

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Germ line DICER1 mutations do not make a major contribution to the etiology of familial testicular germ cell tumours

Germ line DICER1 mutations do not make a major contribution to the etiology of familial testicular germ cell tumours

... both germ-line and somatic mutations in DICER1 that are as- sociated with a range of mainly childhood-onset cancers and dysontogenic or hyperplastic conditions, notably “blastoma”-type tumors such as ...

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Poised chromatin in the mammalian germ line

Poised chromatin in the mammalian germ line

... mammals, germ cells arise at around the time of gastrulation [about embryonic day (E) ...E12.5, germ cells are fate restricted as gamete precursors but are thought to be ‘ pluripotent-like ’ : they maintain ...

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Germ line development in fishes

Germ line development in fishes

... on germ cells in fishes has dealt with three main issues; their embryonic origin, the proliferation, and migration pathway during embryonic and larval develop- ...primordial germ cells (PGCs) have been ...

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Germ line expression of a functional LINE from Drosophila melanogaster: fine characterization allows for potential investigations of trans regulators

Germ line expression of a functional LINE from Drosophila melanogaster: fine characterization allows for potential investigations of trans regulators

... Int I De\' BioI JX 27 33 (1994) 27 Origi/wl "rUde Germ line expression of a functional LINE from Drosophila melanogaster fine characterization allows for potential investigations of trans regulators C[.] ...

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A germ cell determinant reveals parallel pathways for germ line development in Caenorhabditis elegans

A germ cell determinant reveals parallel pathways for germ line development in Caenorhabditis elegans

... Germ cell pools can be determined during embryogenesis Our results provide new insights into the regulation of the PGC cell cycle and its importance in controlling fertility. xnd-1 is the first C. elegans mutant ...

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VIABILITY OF FEMALE GERM-LINE CELLS HOMOZYGOUS FOR ZYGOTIC LETHALS IN DROSOPHILA MELANOGASTER

VIABILITY OF FEMALE GERM-LINE CELLS HOMOZYGOUS FOR ZYGOTIC LETHALS IN DROSOPHILA MELANOGASTER

... The inability of most deficiency-homozygous cells to yield normal eggs probably results from deletion of genes that are necessary for germ-line prolif- eration and/or game[r] ...

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Germ line polysomy in Atractomorpha similis

Germ line polysomy in Atractomorpha similis

... 168 individuals of this species contain a large number of heterochromatic segments on their standard chromosomes, while others carry a large amount of heterochromatin as B chromosomes, a[r] ...

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Drosophila Mitochondrial Genetics: Evolution of Heteroplasmy Through Germ Line Cell Divisions

Drosophila Mitochondrial Genetics: Evolution of Heteroplasmy Through Germ Line Cell Divisions

... A first calculation can be done from the parameters of the regression line for all offspring of female M (Figure 2). At last, t - i, the number of rounds of stem cell divis[r] ...

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Germ line integration of a murine leukemia provirus into a retroviruslike sequence.

Germ line integration of a murine leukemia provirus into a retroviruslike sequence.

... pJE120 and pJE119 were kindly provided by Janet Embretson and Howard Temin, University of quences, 701 Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest Nucleotide sequen[r] ...

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