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Glioblastoma Multiform

Neimark–Sacker bifurcation of a chemotherapy treatment of glioblastoma multiform (GBM)

Neimark–Sacker bifurcation of a chemotherapy treatment of glioblastoma multiform (GBM)

... model, glioblastoma multiform produces after a specific time another tumor pop- ulation which is more resistant to the treatment than the sensitive tumor ...

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Effects of Socioeconomic on Survival for Adult Glioblastoma Multiform Patients in Rio de Janeiro, Brazil, 1999 2009

Effects of Socioeconomic on Survival for Adult Glioblastoma Multiform Patients in Rio de Janeiro, Brazil, 1999 2009

... of glioblastoma multiforme (GBM) patients operated on at public hospital with that of patients operated on at the private ...supratentorial glioblastoma multiform ...

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MicroRNA-652 suppresses malignant phenotypes in glioblastoma multiforme via FOXK1-mediated AKT/mTOR signaling pathway

<p>MicroRNA-652 suppresses malignant phenotypes in glioblastoma multiforme via FOXK1-mediated AKT/mTOR signaling pathway</p>

... Results: miR-652 expression was considerably downregulated in GBM tissues and cell lines. Low miR-652 expression was strongly correlated with Karnofsky performance score and tumor size. Overall survival duration was ...

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Over-expression of BMPR-IB reduces the malignancy of glioblastoma cells by upregulation of p21 and p27Kip1

Over-expression of BMPR-IB reduces the malignancy of glioblastoma cells by upregulation of p21 and p27Kip1

... The p27Kip1 is a potent tumor suppressor gene and an inhibitor of the cell cycle [22]. P27Kip1 plays its sup- pressive role through kinase-cyclin complexes that in- hibit the phosphorylation of Rb that, in turn, results ...

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Glioblastoma expression of vitronectin and the alpha v beta 3 integrin  Adhesion mechanism for transformed glial cells

Glioblastoma expression of vitronectin and the alpha v beta 3 integrin Adhesion mechanism for transformed glial cells

... cerebral glioblastoma biopsy material for the expression of adhesive proteins that might potentiate adhesion and invasion demonstrated tumor cell-associated vitronectin ...the glioblastoma tumor ...in ...

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Integrative analysis of DNA methylation suggests down-regulation of oncogenic pathways and reduced somatic mutation rates in survival outliers of glioblastoma

Integrative analysis of DNA methylation suggests down-regulation of oncogenic pathways and reduced somatic mutation rates in survival outliers of glioblastoma

... from the peritumoral brain parenchyma on treatment-naive multi-parametric MR imaging predict long versus short-term survival in glioblastoma multiforme: preliminary findings. Eur Radiol. ...

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ILKAP, ILK and PINCH1 control cell survival of p53-wildtype glioblastoma cells after irradiation

ILKAP, ILK and PINCH1 control cell survival of p53-wildtype glioblastoma cells after irradiation

... The prognosis is generally poor for patients suffering from glioblastoma multiforme (GBM) due to radiation and drug resistance. Prosurvival signaling originating from focal adhesion hubs essentially contributes to ...

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Characterization of an Orthotopic Rat Model of Glioblastoma Using Multiparametric Magnetic Resonance Imaging and Bioluminescence Imaging

Characterization of an Orthotopic Rat Model of Glioblastoma Using Multiparametric Magnetic Resonance Imaging and Bioluminescence Imaging

... The purpose of my thesis was to develop a multimodality imaging framework using both BLI and mpMRI to characterize the natural progression of orthotopic C6 glioblastoma multiforme expressing red-shifted Luciola ...

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Combination therapy to checkmate Glioblastoma: clinical challenges and advances

Combination therapy to checkmate Glioblastoma: clinical challenges and advances

... GBM: glioblastoma multiforme; GBM-O: glioblastoma multiforme with oligodendroglial component; GSC: glioblastoma stem-like cells; HIF: hypoxia inducible transcription factors; IL: interleukin; IDH1: ...

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Orthogonal targeting of EGFRvIII expressing glioblastomas through simultaneous EGFR and PLK1 inhibition

Orthogonal targeting of EGFRvIII expressing glioblastomas through simultaneous EGFR and PLK1 inhibition

... expressing glioblastoma cells, we next tested whether the PLK1-mediated Rad51 phosphorylation played a significant role in ...U87MG glioblastoma and U2OS osteosarcoma cells (Figure ...

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Nuclear Factor Erythroid 2 Related Factor 2 and Heme Oxygenase 1 Protein Expression and Clinicopathological Features in Glioblastoma

Nuclear Factor Erythroid 2 Related Factor 2 and Heme Oxygenase 1 Protein Expression and Clinicopathological Features in Glioblastoma

... in glioblastoma were investigated to ex- plore the possible impacts of them on the growth of ...of glioblastoma patients were analyzed to summarize their gender, age, tumor recurrence, size of tumor, ...

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Principles of Quantum Mechanics and Laws of Wave Optics from One Mathematical Formula

Principles of Quantum Mechanics and Laws of Wave Optics from One Mathematical Formula

... Keywords Fourier Transform in Quantum Mechanics, Permutation Relations between Operators, Laws of Wave Optics, Diffractions by Multiform Identical Objects.. Introduction From the find t[r] ...

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Long-term Care in Latvia. ENEPRI Research Report No. 81, 15 June 2010

Long-term Care in Latvia. ENEPRI Research Report No. 81, 15 June 2010

... Recent policy achievements are: 1 Multiform measures promoting employment for elderly people have been designed and implemented; 2 A unified system of coordinated measures for promoting [r] ...

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MicroRNA-300 inhibited glioblastoma progression through ROCK1

MicroRNA-300 inhibited glioblastoma progression through ROCK1

... in glioblastoma is still ...in glioblastoma tissues compared with the normal ...of glioblastoma samples compared with the normal ...of glioblastoma patients with lower miR-300 expression level ...

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Peripheral Immunization Blocks Lethal Actions of Vesicular Stomatitis Virus within the Brain

Peripheral Immunization Blocks Lethal Actions of Vesicular Stomatitis Virus within the Brain

... Vesicular stomatitis virus (VSV) is the prototype virus for 75 or more negative-strand RNA viruses in the rhabdovirus family. Some of these viruses, including VSV, can cause neurological impairment or death upon brain ...

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Toward a noncytotoxic glioblastoma therapy: blocking MCP-1 with the MTZ Regimen

Toward a noncytotoxic glioblastoma therapy: blocking MCP-1 with the MTZ Regimen

... effects. Glioblastoma, like other tumors, is not simply a growing autonomous parasitic entity, although it does have elements of ...this. Glioblastoma is more accurately understood as a malignant clone that ...

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RNA nanoparticle as a vector for targeted siRNA delivery into glioblastoma mouse model

RNA nanoparticle as a vector for targeted siRNA delivery into glioblastoma mouse model

... treat glioblastoma, one of the most deadly cancers, requires robust and efficient delivery platform without ...target glioblastoma cells with folate (FA) ligand and deliver siRNA for gene ...patient-derived ...

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The Histone Deacetylase Inhibitor Valproic Acid Lessens NK Cell Action against Oncolytic Virus-Infected Glioblastoma Cells by Inhibition of STAT5/T-BET Signaling and Generation of Gamma Interferon

The Histone Deacetylase Inhibitor Valproic Acid Lessens NK Cell Action against Oncolytic Virus-Infected Glioblastoma Cells by Inhibition of STAT5/T-BET Signaling and Generation of Gamma Interferon

... for glioblastoma (GBM), current regimens result in ap- proximately 15 months of median survival following initial diag- nosis, emphasizing the need for new ...⫽ glioblastoma ⫹ AND ⫹ ...

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Quantum Variational Principle and quantum multiform structure: the case of quadratic Lagrangians

Quantum Variational Principle and quantum multiform structure: the case of quadratic Lagrangians

... Lagrangian multiform variational princi- ple on the quantum level, leading naturally to problem of finding a path integral version of that formalism in order to capture its natural quantum ...

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