globular domain
Mutations that prevent or mimic persistent post-translational modifications of the histone H3 globular domain cause lethality and growth defects in Drosophila
... The family of histone globular domain PTMs also includes three modifications of amino acids that mediate histone–DNA interactions at the nucleosome dyad [12]. The dyad is the point at which DNA is only ...
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Globular domain structure and function of restriction-like-endonuclease LINEs: similarities to eukaryotic splicing factor Prp8
... for globular domain structure, we show that the protein encoded by the Bombyx mori R2 element has two major globular domains: (1) a small globular domain consisting of the N-terminal ...
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NH2 terminal globular domain of human platelet glycoprotein Ib alpha has a methionine 145/threonine145 amino acid polymorphism, which is associated with the HPA 2 (Ko) alloantigens
... The glycoprotein (GP) Ib/IX complex, a prominent platelet GP complex, is the primary receptor for vWF. Previously, we have established that an antigenic polymorphism of platelets, the HPA-2 or Ko alloantigen system, is ...
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Engineered Intermonomeric Disulfide Bonds in the Globular Domain of Newcastle Disease Virus Hemagglutinin-Neuraminidase Protein: Implications for the Mechanism of Fusion Promotion
... We have prevented the formation of the minimal interface form of the protein by the introduction of intermonomeric disulfide bond(s) across the dimer interface in the globular domain. The presence of the ...
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Measles Virus Fusion Machinery Activated by Sialic Acid Binding Globular Domain
... the globular head of ...the globular head are required for fusion activation ...HN globular domain coupled with a functional H stalk region can activate MV F-mediated fusion in- dicates that ...
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The central globular domain of the nucleocapsid protein of human immunodeficiency virus type 1 is critical for virion structure and infectivity.
... central globular domain where the two zinc fingers are brought in close proximity by the RAPRKKG ...this globular structure and more precisely of the RAPRKKG linker in virion structure and ...
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Globular domain of adiponectin: promising target molecule for detection of atherosclerotic lesions
... of globular adiponectin was labeled with the dye via a maleimide ...labeled globular adiponectin was applied for polyacrylamide gel electrophoresis, half thereof for Western blotting ...
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Regulation of chaperone binding and nucleosome dynamics by key residues within the globular domain of histone H3
... Therefore, to determine the mechanism through which these histone residues regulate nucleo- some architecture, we performed chromatin immuno- precipitation (ChIP) analyses on a subset o[r] ...
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Identification of a Region in the Stalk Domain of the Nipah Virus Receptor Binding Protein That Is Critical for Fusion Activation
... the globular domain and the ...HN globular domain to its receptor is neces- sary but not sufficient for activation of F, and this was particularly evident for the chimeric glycoproteins ...and ...
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The crystal structure of the Hazara virus nucleocapsid protein
... arm domain to the N terminus of the globular ...a globular domain and an arm domain. The globular domain is formed from a central core comprising C-terminal helices α13 – ...
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CYK4 promotes antiparallel microtubule bundling by optimizing MKLP1 neck conformation
... The flexible head-to-head coordination in the absence of CYK4 is consistent with the previ- ous electron microscopic observation of dimeric ZEN-4 bound to microtubules [65], in which two motor domains in a single dimer ...
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Structural and Functional Relationship between the Receptor Recognition and Neuraminidase Activities of the Newcastle Disease Virus Hemagglutinin-Neuraminidase Protein: Receptor Recognition Is Dependent on Neuraminidase Activity
... terminal globular domain of the paramyxovirus hemagglutinin-neuraminidase (HN) glycoprotein spike has a number of conserved residues that are predicted to form its neuraminidase (NA) active site, by analogy ...
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Nuclear Magnetic Resonance Structure of the Nucleic Acid-Binding Domain of Severe Acute Respiratory Syndrome Coronavirus Nonstructural Protein 3
... the globular domain of the SARS-CoV NAB with homologues from other group II ...NAB globular domain, and the residue numbering in this domain are ...
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ELM server: A new resource for investigating short functional sites in modular eukaryotic proteins
... The PROSITE database has collected a number of linear protein motifs, representing them as regular expression patterns (5). PROSITE patterns have been very useful, but also suffer from severe overprediction problems and ...
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Extended Structures in Globular Clusters
... and globular clusters into the diffuse halo ...that globular clusters outside the solar circle do not exhibit the correlation between Galactocentric distance and metallicity observed among innermost ...
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Exploring the crowded central region of ten Galactic globular clusters using EMCCDs : variable star searches and new discoveries
... It is worth commenting that, depending on the magnitude level of the horizontal branch of each globular cluster, observa- tions with total exposure times between six to ten minutes were produced (see Sect. 7). To ...
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Observational evidence for radial inhomogeneities in globular clusters
... TABLE OF CONTENTS Page CHAPTER 1 INTRODUCTION 1.1 Introduction 1 1.2 Dynamical properties of Globular Clusters 2 1.3 Evidence for Inhomogeneities within Individual Globular Clusters 4 1.[r] ...
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Influenza Virus H1N1pdm09 Infections in the Young and Old: Evidence of Greater Antibody Diversity and Affinity for the Hemagglutinin Globular Head Domain (HA1 Domain) in the Elderly than in Young Adults and Children
... binding domain (RBD) within the HA1 domain of influenza virus hemag- ...HA1 domain, while the protein sequence within the HA2 stalk domain is highly conserved among multiple influenza virus ...
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Multicolour photometry of globular cluster stars
... advisable to build our scheme around these. The capabilities, of these existing programs, as relevant to our application, were as follŒfs. The plate could be scanned on the Joyce-Loebl and the data, in the form of an ...
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Online Full Text
... the globular grains in the HAZ [18] (see Figure ...the globular grains of the heat affected zone (see Figure 8) as observed in all the samples and the population of the globular grains in the heat ...
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