Glomerular basement membrane Antibody
Glutathione S-transferase Mu 2-transduced mesenchymal stem cells ameliorated anti-glomerular basement membrane antibody-induced glomerulonephritis by inhibiting oxidation and inflammation
... anti-glomerular basement membrane antibody-induced glomeruloneph- ritis (anti-GBM-GN) mouse model, we found that increased expression of glutathione S-transferase Mu 2 (GSTM2) was related to ...
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Synthesis of hydroxyeicosatetraenoic acids and leukotrienes in rat nephrotoxic serum glomerulonephritis Role of anti glomerular basement membrane antibody dose, complement, and neutrophiles
... glomerular basement membrane (GBM) immunoglobulin ...enhanced glomerular production of 5-HETE and LTB4 occurred at 15 min after infusion of anti-GBM Ig, peaked at 1 h, and returned toward ...
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Case Report Fibrillary glomerulonephritis with anti-glomerular basement membrane antibody: a combined glomerular insult
... the glomerular capillary endothelium and ...linear glomerular membranous immunofluores- cent staining with IgG and C3 as well as posi- tive serum level for anti-GBM antibody; findings support the ...
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Interleukin 1 receptor antagonist ameliorates experimental anti glomerular basement membrane antibody associated glomerulonephritis
... anti-glomerular basement membrane (GBM) antibody (Ab) glomerulonephritis (GN) was examined by the administration of a specific IL-1 receptor antagonist ...
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Goodpasture’s syndrome with absence of circulating anti glomerular basement membrane antibodies: a case report
... The three principles of therapy include: a) rapid removal of circulating antibodies, primarily by plasmapheresis; b) pharmacological immunosuppression to prevent further production of antibodies; and c) removal of the ...
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Kallikrein genes are associated with lupus and glomerular basement membrane–specific antibody–induced nephritis in mice and humans
... for glomerular basement membrane [anti-GBM antibodies]), and spontaneous lupus ...anti-GBM antibody–induced and spontaneous lupus ...anti-GBM antibody–induced nephritis were compared ...
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Use of rituximab as an induction therapy in anti-glomerular basement-membrane disease
... Anti-GBM antibody-mediated disease is a fulminant disorder that has a poor prognosis and a mortality rate of up to 90% without ...monoclonal antibody, could be a good alternative to ...
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The acute effects of antiglomerular basement membrane antibody upon glomerular filtration in the rat The influence of dose and complement depletion
... antiglomerular basement membrane antibody (AGBM Ab) in plasma-expanded Munich- Wistar ...the glomerular permeability coefficient (LpA) utilizing direct evaluation of all pertinent pressures, ...
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Macrophage induced glomerular fibrin deposition in experimental glomerulonephritis in the rabbit
... of glomerular fibrin deposition are ...measuring glomerular fibrin deposition and glomerular procoagulant activity in a passive model of the autologous phase of antiglomerular basement ...
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Anti-glomerular basement membrane disease: A case report of an uncommon presentation
... A 22-year-old caucasian woman with a history of smoking (2-3 cigarettes a day), excessive consumption of anti- in lammatory drugs and recurrent urinary tract infection during infancy was referred to our hospital with ...
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Glomerulonephritis mediated by antibody to glomerular basement membrane Immunological, clinical, and histopathological characteristics
... GBM antibody-mediated disease in these patients came from whole kidney or biopsy elutions (15 patients), serologic assays for circulating GBM antibodies by indirect IF (9 of 38 patients), radioimmunoassay (26 of ...
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Anti glomerular basement membrane disease superimposed on membranous nephropathy: a case report and review of the literature
... the glomerular basement membrane antigen and the identification of the pathogenic B and T cell epitopes, along with new insights into the pathogenetic mechanisms at the cellu- lar and molecular ...
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Glomerular basement membrane—reactive antibody in anti lymphocyte globulin
... the glomerular basement membrane of three human homograft recipients who had been treated with equine anti-lymphocyte ...contained glomerular basement membrane-reactive ...human ...
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Nephritogenicity of antibodies to proteoglycans of the glomerular basement membrane I
... of glomerular basement ...isolated, basement membranes were prepared, proteoglycans extracted, and purified core protein was ...The antibody showed precise reactivity with the ...
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Kallikreins and lupus nephritis
... Anti–glomerular basement membrane (GBM) antibodies have been used to induce experimental nephritis in mice ...anti-GBM antibody–induced nephritis and lupus ...anti-GBM antibody–induced ...
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Pulmonary renal syndrome in a child with coexistence of anti-neutrophil cytoplasmic antibodies and anti-glomerular basement membrane disease: case report and literature review
... cytoplasmic antibody (ANCA)-associated vas- culitis (AAV), anti-glomerular basement membrane (GBM) disease, and Henoch-Schonlein purpura ...
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Acute effects of antiglomerular basement membrane antibody on the process of glomerular filtration in the rat
... resistances increased and rpf fell from 221+/-25 to 90+/-9 nl/min per g kidney wt (P less than 0.001) but the hydrostatic pressure gradient across the glomerular membrane deltaP = PG - Pt) increased from ...
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Systemic Lupus Erythematosus STUDIES OF THE ANTIBODIES BOUND TO SKIN
... This antibody is concentrated on the skin and glomerular basement membrane in proportion to the total serum IgG ...antinuclear antibody, a basement membrane ...
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CD4+ T cells specific to a glomerular basement membrane antigen mediate glomerulonephritis
... Some studies have focused more on the role of anti- gen-specific T cells in anti-GBM GN. Disease suscepti- bility has been strongly linked to MHC class II, sug- gesting the potential roles of the antigen-specific T cells ...
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Clinicopathological analysis of proliferative glomerulonephritis with monoclonal IgG deposits in 5 renal allografts
... H antibody) and infectious etiologies. Despite the glomerular deposits are monoclonal in nature, serum monoclonal protein (M spike) and bone marrow aspirate examination are all negative in cases ...
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