Glycoprotein complex
Arenavirus Stable Signal Peptide Is the Keystone Subunit for Glycoprotein Complex Organization
... nascent glycoprotein at intermediate maturation stages, as transfection efficiencies were comparable under all ...the glycoprotein completely lacks its native SSP, demonstrated SSP was not re- quired for ...
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Stabilization of the Soluble, Cleaved, Trimeric Form of the Envelope Glycoprotein Complex of Human Immunodeficiency Virus Type 1
... One reason to prepare recombinant forms of the native Env complex is for structural studies. At present, structural infor- mation on HIV-1 Env is limited to core fragments of gp120 in the CD4-associated ...
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Human Herpesvirus 6 Glycoprotein Complex Formation Is Required for Folding and Trafficking of the gH/gL/gQ1/gQ2 Complex and Its Cellular Receptor Binding
... using a previously described primer pair (2). The CD46-expressing vector pM18S was a generous gift from T. Seya, Hokkaido University, Hokkaido, Japan (17). Antibodies. To generate anti-HHV-6 antibodies, BALB/c mice were ...
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A multigene family encodes the human cytomegalovirus glycoprotein complex gcII (gp47-52 complex).
... For further analysis of the HXLF gene products, mRNA from all five ORFs was translated in the presence of CPM and the products were immunoprecipitated with either monoclonal antibody 9E1[r] ...
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Subunit structure of the glycoprotein complex of avian tumor virus.
... By contrast, electrophoresis on SDS-gel of the peak eluted from the first fraction of the alkaline urea-gel of the reduced and alkylated viral glycoprotein yielded predominantly gp37 Fig[r] ...
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Processing of the gp55-116 envelope glycoprotein complex (gB) of human cytomegalovirus.
... From these results, the intracellular processing of the gp55-116 complex appears to involve N-linked glycosylation of the Mr 105,000 nonglycosylated precursor to an abundant glycosylated[r] ...
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Synthesis and processing of the Marek's disease herpesvirus B antigen glycoprotein complex.
... These collective data obtained from the cell-free and in vivo studies with polyclonal and monoclonal antibodies reactive with MDHV-B are consistent with the concept that pr44, the initia[r] ...
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Complex formation of platelet thrombospondin with histidine rich glycoprotein
... thrombospondin-histidine-rich glycoprotein complex. Histidine-rich glycoprotein complexed with thrombospondin was capable of binding heparin and neutralizing the anticoagulant activity of heparin in ...
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Structural Comparison of HIV-1 Envelope Spikes with and without the V1/V2 Loop
... A recombinant human immunodeficiency virus type 1 envelope glycoprotein complex stabilized by an intermolecular disulfide bond between the gp120 and gp41 subunits is an antigenic mimic o[r] ...
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Identification of the murine cytomegalovirus glycoprotein B gene and its expression by recombinant vaccinia virus.
... To test whether the proteins of the major envelope glycoprotein complex are the translation products of the identified gB gene, the protein expressed by the recombinant vaccinia virus Va[r] ...
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Antigenic characterization of flavivirus structural proteins separated by isoelectric focusing.
... The envelope glycoprotein contains multiple antigenic determinants: strongly reactive type-specific and complex-reactive antigens, as well as the flavivirus group determinants.. The flav[r] ...
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Herpesvirus Interference with Major Histocompatibility Complex Class II-Restricted T-Cell Activation
... Immune evasion strategies have been identified for mem- bers of all three subfamilies, for example, herpes simplex virus (HSV; an alphaherpesvirus), human cytomegalovirus (HCMV; a betaherpesvirus), and Epstein-Barr virus ...
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Regulation of susceptibility and cell surface receptor for the B-lymphotropic papovavirus by N glycosylation.
... Here we describe that inhibition of cellular glycoprotein N glycosylation by tunicamycin as well as blocking of the formation of complex and hybrid N oligosaccharide chains by deoxymanno[r] ...
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The Human Cytomegalovirus UL74 Gene Encodes the Third Component of the Glycoprotein H-Glycoprotein L-Containing Envelope Complex
... gCI complex, which contains a dimer of gB in association with cellular annexin II (4, 23, 43), was structurally and genetically ...gCII complex, which has a sug- gested role in heparin binding, has at least ...
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Structural Transitions of the Conserved and Metastable Hantaviral Glycoprotein Envelope
... Gn glycoprotein sequences separates hantavirus species according to host ...HTNV glycoprotein precursor (above) and crystal structure of the HTNV Gn ectodomain to ...
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The Surface Conformation of Sindbis Virus Glycoproteins E1 and E2 at Neutral and Low pH, as Determined by Mass Spectrometry-Based Mapping
... Protein domains exposed on the surface of the virus spike complex at low pH. Having identified the amino acid sequences accessible to proteases at neutral pH, we next conducted ex- periments to determine how the ...
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Platelet thrombospondin forms a trimolecular complex with plasminogen and histidine rich glycoprotein
... inhibited complex formation of the other with TSP, 10 mM epsilon- amino-n-caproic acid selectively blocked incorporation of Plg into the complex, suggesting that TSP contains independent binding sites for ...
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Varicella-zoster virus glycoprotein oligosaccharides are phosphorylated during posttranslational maturation.
... The few complex-type glycopeptides recovered from the 77-kDa species, however, contained mannose phosphate residues, indicating that phosphorylation of the viral glycoprotein oligosaccha[r] ...
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Binding of fibrinogen to human monocytes
... glycoprotein IIb/IIIa complex (10E5) do not bind fibrinogen and have no procoagulant activity. Metabolic studies with [35S]methionine revealed that cultured monocytes actually synthesize a surface antigen ...
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Complex Formation by Glycoproteins M and N of Human Cytomegalovirus: Structural and Functional Aspects
... in complex formation by generating carboxyl-terminal truncations at sites selected to be outside the predicted seven transmembrane domains in this ...the complex to a distal secretory ...to complex ...
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