GO terms associated with down-regulated genes
GP73 is down regulated in gastric cancer and associated with tumor differentiation
... was associated with tumor ...be associated with maintaining the structural integrity of the Golgi complex during onco- genesis ...strongly associated with tumor size, vein invasion and tumor dif- ...
6
Identification of genes down-regulated during lung cancer progression: A cDNA array study
... Lung cancer remains a major health challenge in the world. Despite improvements in staging and the inte- grated application of surgery, radiotherapy, and chemo- therapy, the 5-year survival rate for individuals with lung ...
6
Elevated expression of prostate cancer-associated genes is linked to down-regulation of microRNAs
... pathologists to achieve definitive diagnosis of PCa [7,8]. It has been shown that AMACR can modify the growth of PCa cells in an androgen-independent manner [9]. EZH2 (enhancer of zeste homolog 2) is a member of the ...
14
SOX7 is down-regulated in lung cancer
... We initially performed CN analysis of 9 NSCLC samples and 8 NSCLC cell lines, each with an EGFR mutation. Their pattern of genome alterations were compared to the SNP-Chip copy number changes found in 56 NSCLC in the ...
11
Conserved IKAROS-regulated genes associated with B-progenitor acute lymphoblastic leukemia outcome
... are associated with poor outcome in B lineage acute lymphoblastic leukemia (B-ALL) and occur in >70% of the high-risk Bcr-ABL1 + (Ph + ) and Ph-like disease ...roS-repressed genes. notably, high expression ...
19
Original Article Serum miR-133a is down-regulated and associated with the diagnosis of patients with gastric cancer
... In the present study, we first detected the expression level of serum miR-133a of GC patients and healthy controls. And the result displayed that miR-133a was significantly down-regulated in GC patients ...
6
Selection for retroviral insertions into regulated genes.
... The issue of background “noise” associated with the use of the HyTK-based gene traps was addressed as follows. Cells were infected with pROSAHyTK and seeded in medium with G418 and ganciclovir. After individual ...
7
Developmentally regulated genes in Trypansoma Cruzi
... identify those interacting factors in order to understand the biochemical function of MET3 and its role during metacyclogenesis. Based on the results from sequence analysis presented in this study, it seems prob able ...
243
Original Article Promoter hypermethylation mediates the down-regulated expression of ADAMTS9 and is associated with the prognosis in hepatocellular carcinoma
... suppressor genes such as APC [21], P16 [22] and RIZ1 [23], it was found that the methylation of the anti-onco- gene promoter region could lead to the decrease of gene protein ...was down-regulated in ...
11
GTPase regulator associated with the focal adhesion kinase (GRAF) transcript was down-regulated in patients with myeloid malignancies
... In this study, we demonstrated that the expression level of GRAF transcript was decreased in primary leu- kemic cells of all types of myeloid malignancies. Boje- sen et al [10] found that GRAF promoter was ...
5
Original Article LncRNA HMlincRNA717 is down-regulated in non-small cell lung cancer and associated with poor prognosis
... HMlincRNA717 down-reg- ulation and poor prognosis may not only be used for identifying NSCLC patients with higher risk of early tumor relapse but also for providing valuable clues to understand the possible ...
6
Original Article MicroRNA-148b is down-regulated in non-small cell lung cancer and associated with poor survival
... Survival analysis Kaplan-Meier survival analysis and log-rank test demonstrated a significant difference in the outcomes of patients who were divided into two groups based on their miR-148b expres- sion level. ...
6
Gene expression profiling identifies eleven DNA repair genes down regulated during mouse neural crest cell migration
... repair genes to be the most highly expressed in pre-migratory ...11 genes has not been previously reported in mouse ...11 genes decreased drastically in expression of adult P90 (in the AM), compared ...
9
The kallikrein 14 gene is down-regulated by androgen receptor signalling and harbours genetic variation that is associated with prostate tumour aggressiveness
... be associated with tumour characteristics such as higher stage and Gleason ...of genes, although detailed studies of androgen regulation of KLK14 in prostate cancer have not been undertaken to ...KLK ...
10
Statistical modelling of transcript profiles of differentially regulated genes
... in terms of a postulated mechanism driving the observed gene expres- sion responses, in this case potentially quantifying the relationship between transcript synthesis and degrada- ...between genes using a ...
17
Monitoring of the environmental influence on stress regulated genes in oak
... and genes involved in protective and detoxification processes as well as senescence-associated genes are ...expressed genes (Kreps et ...
153
UBE2Q1, as Down Regulated Gene in Pediatric Acute Lymphoblastic Leukemia
... UBE2Q2 genes, and reported their differential expression in some human ...up regulated in hypo - pharyngeal tumors (10), breast cancer (11), Acute Lymphoblastic Leukemia (12) and colon cancer epithelium ...
7
The mechanism of apoliprotein A1 down-regulated by Hepatitis B virus
... (DNMT) whose activities are inhibited by DNA methyl- transferases inhibitor 5-aza-dC [19, 20]. A recent study demonstrated the mRNA levels of DNMT1, DNMT3A and DNMT3B in HBV-associated tissues were signifi- cantly ...
7
Imprinting genes associated with endometriosis
... of genes are essential for the decid- ualization and implantation processes, but up-regulation of a small number of them, including IGF, IGFBP, PRL, HOXA10, FOXO1, C/EBPbeta, IL11 and LIF, are im- portant for this ...
13
The beta-3 adrenergic agonist (CL-316,243) restores the expression of down-regulated fatty acid oxidation genes in type 2 diabetic mice
... significant down- regulation of FA oxidation genes in the skeletal muscle and adipose tissues of MKR mouse model of Type 2 diabetes, and in the pre-diabetic insulin resistant liver of these ...in ...
14