Goto kakizaki
Diabetes disease progression in Goto-Kakizaki rats: effects of salsalate treatment
... Abstract: This study investigates the antidiabetic effects of salsalate on disease progression of diabetes in non-obese diabetic Goto-Kakizaki (GK) rats, an experimental model of type 2 diabetes. Salsalate ...
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Effects and mechanism of duodenal-jejunal bypass and sleeve gastrectomy on GLUT2 and glucokinase in diabetic Goto–Kakizaki rats
... In this experiment we use non-obese diabetic Goto– Kakizaki (GK) rats as the experimental animal. There are two methods: duodenal-jejunal bypass (DJB) reduces absorption, and sleeve gastrectomy (SG) limits ...
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Transcriptomic alterations in the heart of non-obese type 2 diabetic Goto-Kakizaki rats
... rat: Goto-Kakizaki rat; GLUT4: glucose transporter 4; GO: gene ontology; Gpc3: glypican 3; Gsta2: glutathione S-transferase alpha 2; HOMA-IR: homeostasis model assessment- estimated insulin resistance; ...
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Salidroside contributes to reducing blood pressure and alleviating cerebrovascular contractile activity in diabetic Goto-Kakizaki Rats by inhibition of L-type calcium channel in smooth muscle cells
... As a well-known traditional herb medicine, Rhodiola rosea (Rhodiola) has been demonstrated to have beneficial effects for high altitude-related symptoms [8]. Recently, it has been reported that Salidroside (SAL), the ...
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Stem cells from human exfoliated deciduous teeth ameliorate type II diabetic mellitus in Goto-Kakizaki rats
... Background: By 2030, diabetes mellitus (DM) will be the 7th leading cause of death worldwide. Type 2 DM (T2DM) is the most common type of DM and is characterized by insulin resistance and defective β-cell secretory ...
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Original Article Effects on high cholesterol-fed to liver, retina, hippocampus, and Harderian gland in Goto-Kakizaki rat
... in Goto-Kakizaki rat on liver (microvesicular steatosis) and Harderain gland (tubular lesions) were related to hyperglycemic effect rather than cholesterolemic ...
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Consequences of exercising on ischemia–reperfusion injury in type 2 diabetic Goto-Kakizaki rat hearts: role of the HO/NOS system
... sedentary Goto-Kakizaki rats, GK run voluntary wheel-running Goto-Kakizaki ...sedentary Goto-Kakizaki rats, GK run voluntary wheel-running Goto-Kakizaki ...
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Reduced up-regulation of the nitric oxide pathway and impaired endothelial and smooth muscle functions in the female type 2 diabetic goto-kakizaki rat heart
... the Goto- Kakizaki (GK) rat, a highly inbred strain derived from outbred, glucose-intolerant Wistar rats that spontan- eously develop type 2 diabetes within the first few weeks of age ...
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Interdependency between mechanical parameters and afferent nerve discharge in remodeled diabetic Goto-Kakizaki rat intestine
... Objective: We aimed to characterize the stimulus–response function of afferent fibers innervat- ing the jejunum in the Goto-Kakizaki (GK) type 2 diabetic rat model. A key question is whether changes in ...
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ARA290 Improves Insulin Release and Glucose Tolerance in Type 2 Diabetic Goto-Kakizaki Rats
... Since prolonged treatment with EPO can increase the hematocrit and provoke thrombosis, we have studied an EPO analogue, ARA290 (8). This 11 amino acid peptide lacks hematopoietic action, binds to the IRR and protects a ...
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Exercise training enhanced myocardial endothelial nitric oxide synthase (eNOS) function in diabetic Goto-Kakizaki (GK) rats
... Different mechanisms of diabetic-induced NO dysfunc- tion have been proposed and central to most of them are significant changes in eNOS function as the rate-limiting step in NO bioavailability. Several studies have ...
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Effect of phlorizin on metabolic abnormalities in Spontaneously Diabetic Torii (SDT) rats
... In Goto-Kakizaki rats, which is a nonobese animal model of type 2 diabetes, phlorizin decreased the blood glucose levels and improved the glucose stimu- lated insulin secretion ...
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Regressed three-dimensional capillary network and inhibited angiogenic factors in the soleus muscle of non-obese rats with type 2 diabetes
... changes in the levels of angiogenic factors may be asso- ciated with diabetes-related microangiopathy has not been thoroughly examined. This possibility could involve multifactorial processes, i.e., changes in the levels ...
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Opisthotonic Posturing With Neuromuscular Irritability Attributable to 4-Aminopyridine Ingestion by a Healthy Pediatric Patient
... Opisthotonic Posturing With Neuromuscular Irritability Attributable to 4-Aminopyridine Ingestion by a Healthy Pediatric Patient.. Larissa Velez, MD*‡; Farshad Shirazi, MD‡; Collin Goto, [r] ...
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Structural, Electrical and Optical Characterization of SrIrO3 Thin Films Prepared by Laser Ablation
... Structural, Electrical and Optical Characterization of SrIrO3 Thin Films Prepared by Laser-Ablation Yuxue Liu, Hiroshi Masumoto and Takashi Goto Institute for Materials Research, Tohoku [r] ...
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Immunohistochemical expression of CD44s in human neuroblastic tumors: Moroccan experience and highlights on current data
... neuroblastoma GOTO cells, of which a cell adhesion molecule CD44 expression is usually suppressed, could be induced to differentiate into Schwannian cells and neuronal cells in the presence of ...
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MT Microsystems Pascal MT+ Release 5 Oct80 pdf
... The following are the reserved words in Pascal/MT+: MOD, NIL, IN, OR, AND, NOT, IF, THEN, ELSE, CASE, OF, REPEAT, UNTIL, WHILE, DO, FOR, TO, DOWNTO, BEGIN, END, WITH, GOTO, CONST, VAR, T[r] ...
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Diffuse Connections: Making Sense of Smell in Canadian Diasporic Women's Writing
... Representations of smell are particularly prevalent in the work of Shani Mootoo, Hiromi Goto, and Larissa Lai, three prominent Canadian women writers whose work explores the complexiti[r] ...
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Effects of As Cast Holes on Cooling Patterns in Directional Solidification of Plate Castings
... Effects of As Cast Holes on Cooling Patterns in Directional Solidification of Plate Castings Ikuzo Goto* and Setsuo Aso Department of Materials Science, Graduate School of Engineering Sc[r] ...
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Microstructure and Electrical Conductivity of SrRuO3 Thin Films Prepared by Laser Ablation
... Microstructure and Electrical Conductivity of SrRuO3 Thin Films Prepared by Laser Ablation Akihiko Ito* , Hiroshi Masumoto and Takashi Goto Institute for Materials Research, Tohoku Unive[r] ...
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