Granule cell
Axonin-1/TAG-1 is required for pathfinding of granule cell axons in the developing cerebellum
... the granule cells, all cells are born in the ventricular zone and migrate radially to reach their final destination in the mature cerebellum ...EGL, granule cell precursors differentiate in the inner ...
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Segmental identity and cerebellar granule cell induction in rhombomere 1
... a cell-depleted EGL RCASBP(B)Hoxa2 retrovirus was injected into the neural tube of ...Cerebellar granule cell precursors are generated at the rhombic lip (E6 onwards), which comprises the interface ...
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Overlapping functions of the cell adhesion molecules Nr-CAM and L1 in cerebellar granule cell development
... affect granule cell develop- ment? When granule cells become postmitotic, they first ex- press TAG-1, and then L1 and Nr-CAM (Kuhar et ...mature granule cells in the IGL. As granule ...
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The granule cell density of the dentate gyrus following administration of Urtica dioica extract to young diabetic rats
... the granule cells were measured and compared in the four ...lower cell density than the controls (p > ...for granule cell loss in the diabetic rat dentate gyrus, which can ameliorate ...
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Clonal analysis reveals granule cell behaviors and compartmentalization that determine the folded morphology of the cerebellum
... gcp cell division when analyzed at ...oriented cell divisions may change over time; however, the bias that we observed at P4, when the EGL is highly proliferative, strongly suggests that the orientation of ...
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TSHZ1 dependent gene regulation is essential for olfactory bulb development and olfaction
... mitral cell layer (Figure 8, B, G, and L). Several markers of the granule cell layer — including syntabulin (Sybu), sorting nexin 7 (Snx7), Krox20/Egr2, and the immediate early gene Arc — were ...
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Bmp2 antagonizes sonic hedgehog mediated proliferation of cerebellar granule neurones through Smad5 signalling
... of granule cell precursors in vitro. However, cell proliferation/ differentiation of cerebellar granule neurones is also finely regulated by extracellular matrix glycoproteins (Graus-Porta et ...
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How to make a hippocampal dentate gyrus granule neuron
... decreased granule cell neurogenesis due to INP depletion (Hodge et ...DG granule neuronal fate is distinct from other classes of DG or glutamatergic neurons and depends on activity of Prox1, a ...
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Search | Preprints
... raw cell counts per section per animal for Ki-67, BrdU were divided by the area of the granule cell layer and are indicated as cells per mm2 of the granule cell layer per ...entire ...
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Multiple developmental programs are altered by loss of Zic1 and Zic4 to cause Dandy Walker malformation cerebellar pathogenesis
... postnatal granule cell progenitor ...of granule cell ...Purkinje cell gene expression were ...Purkinje cell topography during late embryonic stages; however, this phenotype was ...
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C3aR signaling and gliosis in response to neurodevelopmental damage in the cerebellum
... promote granule neuron survival during postnatal cerebellar ...cerebellar granule neuron loss and phagocyte invasion over the first 10 days following ...external granule cell layer, as well as ...
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Neurogenesis, cell death and regeneration in the adult gymnotiform brain
... It has been hypothesized that the proliferation zones in the molecular layer at the midline of the corpus cerebelli and valvula cerebelli pars medialis, where most of the cells of these two cerebellar subdivisions are ...
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Examination of PHB Depolymerases in Ralstonia eutropha: Further Elucidation of the Roles of Enzymes in PHB Homeostasis
... in granule/cell area ratios (Table 5) and granule counts (Table 6) in strains Re1110 (ΔphaZ2) and Re1112 (ΔphaZ1ΔphaZ2), when compared to wild type, suggest that PhaZ2 could indeed have a ...
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Electrophysiological and Morphological Identification of Action Potential Generating Secretory Cell Types Isolated from the Salivary Gland of Ariolimax
... Microelectrode recordings from identified cell types have demonstrated: 1 the large granule cell type granule diameter = 8-12/im displays a characteristic long duration, slow rise time a[r] ...
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BK virus encephalopathy and sclerosing vasculopathy in a patient with hypohidrotic ectodermal dysplasia and immunodeficiency
... cerebellar granule cell neurons as JC virus granule cell neuronopathy (JCV- GCN), which is associated with JCV variants harboring a small deletion in the VP1 capsid protein [22, 33], and in ...
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Transit amplification in the amniote cerebellum evolved via a heterochronic shift in NeuroD1 expression
... Despite these insights, relatively little is known about the emergence of transit amplification as a developmental strategy. In the cerebellum, there is a dramatic disjunction between developmental strategies used in ...
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The mechanisms for pattern completion and pattern separation in the hippocampus
... grid cell representations, which would not be suitable for asso- ciation of an object or reward with a place to form an episodic memory, transformed into a place representation that would be appropriate for this ...
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Relative Neurotropism of a Recombinant Rhabdovirus Expressing a Green Fluorescent Envelope Glycoprotein
... A new recombinant vesicular stomatitis virus (rVSV) that expresses green fluorescent protein (GFP) on the cytoplasmic domain of the VSV glycoprotein (G protein) was used in the mouse as a model for studying brain ...
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Expression of tryptophan 2,3-dioxygenase in mature granule cells of the adult mouse dentate gyrus
... hippocampal granule cells fail to mature and remain in an immature state ...the granule cells of CaMKIIa+/- mice and the higher expression of tdo in the hippocam- pus compared with several regions of the ...
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Different activation signals induce distinct mast cell degranulation strategies
... exteriorized granule structures) fluorescence was measured, at the single-cell level, using time-lapse confocal microscopy in a controlled atmosphere (37°C and 5% CO 2 ...budding granule structure at ...
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