growth and differentiation factor-5
Region-specific role of growth differentiation factor-5 in the establishment of sympathetic innervation
... that growth differentiation factor 5 (GDF5), a widely expressed member of the transforming growth factor beta (TGF β ) superfamily required for limb development, promoted axon ...
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The Effect of Growth Differentiation Factor-5, 6, 7 in Chondrogenic Cell Differentiation of ATDC-5
... chondrogenic differentiation marker genes (Sox9, Collagen Type II (Col2), Collagen Type X (ColX), and Aggrecan) were analyzed using real-time quantitative RT-PCR (MX3005P, Agilent Technologies, Tokyo, Japan); ...
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A genetic association study between growth differentiation factor 5 (GDF 5) polymorphism and knee osteoarthritis in Thai population
... Our study has shown the statistically significant associa- tion between polymorphism in promoter of GDF5 gene ( rs143383 ) and knee osteoarthritis in Thai population. We found that T allele in GDF5 polymorphism was a ...
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Growth differentiation factor 6 and transforming growth factor beta differentially mediate mesenchymal stem cell differentiation, composition, and micromechanical properties of nucleus pulposus constructs
... Growth differentiation factor 5 (GDF5/BMP-14/CDMP- 1) and growth differentiation factor 6 (GDF6/BMP-13/ CDMP-2) are members of the TGF superfamily and are as- sociated ...
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Growth differentiation factor 9 and bone morphogenetic protein 15 expression in previtellogenic oocytes and during early embryonic development of Yellow-tail Kingfish Seriola lalandi
... transforming growth factor β super family (TGF-β), GDF9 and BMP15 ...These growth factors stimulate the proliferation of granu- lose cells, but also suppress follicle stimulating hormone ...
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Growth Factor-free Chondrogenic Differentiation from Induced
... pluripotent stem cells (hiPSCs) into chondrocytes and cartilage pellet using minicircle vectors.. Minicircles are 5.[r] ...
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Genetic analysis of female infertility with the effect of human bmp15 and gdf9 genes: a review
... transforming growth factor b (TGF) superfamily and is exclusively expressed in ...and differentiation (Vireque et ...female, growth and differentiation factor plays a critical ...
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Nerve growth factor: role in growth, differentiation and controlling cancer cell development
... possible hypothesis might encompass a different bio- logical preparation and/or composition of NGF formula- tion, the not-homogeneous study populations (in terms of age, onset and severity as well as clinical history of ...
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Serum Growth Differentiation Factor 15 in Patients with Ulcerative Colitis
... the 5’ or 3’untranslated region (UTR) known as iron-responsive elements ...erythroid 5-aminolevulinic acid synthase (Cox et ...the 5’ end (Zheng et ...
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Developmental tumours, early differentiation and the transforming growth factor beta superfamily
... The current models for signal transduction by ligands of the TGF β superfamily via serine/threonine kinase receptors and Smads that lead to transcriptional regulation of target genes and ultimately changes in cell ...
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Activin signaling as an emerging target for therapeutic interventions
... Activin signals are transmitted through two types of trans- membrane serine/threonine kinase receptors, type I and type II activin receptors in target cells [1,4]. Activin recep- tors are prototypes of single-pass ...
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Epidermal growth factor enhances osteogenic differentiation of dental pulp stem cells in vitro
... osteogenic differentiation analysis using reverse transcriptase-polymerase chain reaction (RT-PCR) Gene Sequence of oligonucleotides (5 ’ - 3 ’ ) Tm °C β -Actin Forward: ...
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Diclofenac and triamcinolone acetonide impair tenocytic differentiation and promote adipocytic differentiation of mesenchymal stem cells
... tenocytic differentiation of the fibroblast-like C3H10T1/2 ...transforming growth factor beta superfamily, which is a group of growth factors known to induce growth and ...
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The role of TGF superfamily gene expression in the regulation of folliculogenesis and oogenesis in mammals: a review
... a growth factor signalling cascade that highly regulates the proliferation and differentiation of ovarian cells (Figure 1), (Nagashima et ...important growth factors include genes of the TGFB ...
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Cord blood-endothelial colony forming cells are immunotolerated and participate at post-ischemic angiogenesis in an original dorsal chamber immunocompetent mouse model
... Arachidonate 5-lipoxygenase; APB: Adult peripheral blood; bFGF: Basic fibroblast growth factor; CB: Cord blood; CBMCs: Cord blood mononuclear cells; CD: Cluster differentiation; CFU-ECs: ...
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<p>Growth and differentiation factor 15 regulates PD-L1 expression in glioblastoma</p>
... Glioblastoma (GBM) is the most common primary malignant tumor in the central nervous system, with an incidence of approximately 3/100,000 persons per year. 1,2 The standard therapy for newly diagnosed GBM involves ...
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Original Article Effects of insulin-like growth factor 2 and its receptor expressions on corneal repair
... proliferation, differentiation and migration ...tion, differentiation and migration into injury sites, where it induces the expression of epi- thelial markers ...
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Development of Simple Protocol for Generation of Functionally Active Hepatocyte-like Cells from Human Adipose Tissue-derived Stem Cells
... survival factor and involving in cell proliferation and differentiation ...hepatic differentiation of MSCs and these pretreated cells have been shown as having the capacity to improve liver function ...
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<p>Dental Pulp Stem Cells: Advances to Applications</p>
... key factor for tissue ...the differentiation of these ...major growth factors (bFGF, TGF- β , NDF, BMPs, and PDGF), scaffolds, and mitochondrial properties within the research fi eld of ...
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Differentiation induction and growth factor responses of murine myeloid leukemias
... Jetten AM, Jetten MER and Sherman MI 1979 Stimulation of several murine embryonal carcinoma cell lines by retinoic acid Experimental Cell Research 124 381 Jones AL and Millar JL 1989 Gro[r] ...
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