Growth Factor-Beta
Hepatic processing of transforming growth factor beta in the rat Uptake, metabolism, and biliary excretion
... Transforming growth factor beta (TGF beta), a recently discovered polypeptide, modulates growth of normal and neoplastic ...TGF beta, we performed studies to examine the hepatic ...
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Recombinant latent transforming growth factor beta 1 has a longer plasma half life in rats than active transforming growth factor beta 1, and a different tissue distribution
... Transforming growth factor beta 1 (TGF-beta 1) is a key regulator of cell growth and differentiation. Under normal physiological conditions, it is made as a biologically latent complex ...
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Coordinate regulation of transforming growth factor beta gene expression and cell proliferation in hamster lungs undergoing bleomycin induced pulmonary fibrosis
... The number of mesenchymal cells, as well as their ability to synthesize extracellular matrix (ECM) components, greatly increase in the interstitium of fibrotic lungs. We have previously shown that the transcription of ...
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Transforming growth factor beta-1 expression in macrophages of human chronic periapical diseases.
... The TGF-b superfamily consists of more than 40 members, which are similar in structure and function. TGF-b is secreted as a homodimer, and its ligands include TGF-b, activin, and bone morphogenetic protein (BMP), which ...
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Modulation of transforming growth factor beta signalling pathway genes by transforming growth factor beta in human osteoarthritic chondrocytes: involvement of Sp1 in both early and late response cells to transforming growth factor beta
... The present study enlightens a mechanism of feedback loop controlling TGF b responses in human OA chon- drocytes. Contrary to previous studies, which examined one particular gene, we investigated the TGFb-induced ...
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Transforming growth factor beta 1 suppresses acute and chronic arthritis in experimental animals
... TGF beta 1 suppressed the evolution of arthritis even when administration was begun after the acute phase of the ...TGF beta 1 treatment greatly reduced inflammatory cell infiltration, pannus formation, and ...
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Transforming growth factor beta and breast cancer: Tumor promoting effects of transforming growth factor β
... blocks growth inhibition by TGF- β , but also subverts this pathway into one that can stimulate epithelial-to-mesenchymal transdifferentiation [17 • ,20 • ...1-mediated growth inhibition and p21/Cip1 pro- ...
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Transforming growth factor-beta receptor signalling is modulated by integrin-linked kinase
... keratinocyte growth medium (Ca 2+ -free EMEM supplemented with 8% Chelex resin- treated FBS, 100U/ml penicillin , 100μg/ml streptomycin, 74 ng/ml hydrocortisone, 5 μg/ml insulin, ...the growth medium was ...
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Abstract: Crosstalk between the BMP and TGF- signaling pathways regulates many complex
... Estrogen inhibits transforming growth factor beta signaling by. 223[r] ...
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Expression of epidermal growth factor, transforming growth factor-β1 and adiponectin in nipple aspirate fluid and plasma of pre and post-menopausal women
... epidermal growth factor (EGF), transforming growth factor-beta 1 (TGF- β 1), and adiponectin and evaluated menopausal status and body mass index (BMI) as potential modifying ...
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and vascular endothelial growth factor in filtering bleb after trabeculectomy
... Transforming growth factor beta-2 (TGF-β 2 ) and Vascular endothelial growth factor (VEGF) in filtering bleb tissues after trabeculectomy on rabbit eyes, and to discuss their ...
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The molecular basis of hypertrophic scars
... Transforming growth factor-β (TGF-β) plays a pivotal role in HTS formation TGF-β is one of the most im- portant growth factors that regulate tissue regeneration, cell differentiation, embryonic ...
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Effects of Non-Collagenous Proteins, TGF-β1, and PDGF-BB on Viability and Proliferation of Dental Pulp Stem Cells
... of growth factors such as platelet-derived growth factor BB (PDGF-BB), transforming growth factor beta 1 (TGF-β1) and other bio-active molecules, sequestered during ...
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Fat extract promotes angiogenesis in a murine model of limb ischemia: a novel cell-free therapeutic strategy
... hepatocyte growth factor (HGF), granulocyte – macrophage colony-stimulating factor (GM-CSF), trans- forming growth factor beta (TGF- β ), and insulin-like growth ...
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Safety study: is there a pathologic IGF-1, PDGF and TGF-ß cytokine expression caused by adjunct BMP-7 in tibial and femoral non-union therapy?
... like growth factor 1 (IGF-1), platelet-derived growth factor AB (PDGF-AB) and transforming growth factor beta (TGF-β) were compared between patients with the gold standard ...
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Lack of transforming growth factor β signaling promotes collective cancer cell invasion through tumor stromal crosstalk
... Transforming growth factor beta (TGF- b ) is a pleiotro- pic cytokine that regulates growth arrest, cell motility, development, and differentiation ...transforming growth ...
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Differential expression of transforming growth factors alpha and beta in rat intestinal epithelial cells
... transforming growth factor alpha (TGF alpha), and transforming growth factor beta (TGF beta) was assessed in isolated primary rat intestinal epithelial cells as well as a rat ...
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Effects of platelet derived growth factor and other polypeptide mitogens on DNA synthesis and growth of cultured rat liver fat storing cells
... platelet-derived growth factor (PDGF), epidermal growth factor (EGF), transforming growth factor (TGF)-alpha and TGF-beta, and basic fibroblast growth factor ...
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Expressions of Growth Factors in Autologous Derived Platelet-Rich Plasma and Platelet-Poor Plasma; Implication for Tissue Reparation and Wound Healing
... each factor. Any growth factor present was bound by the immobilized ...each growth factor was added to the ...bound growth factor in the first ...
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Post-transcriptional regulatory network of epithelial-to-mesenchymal and mesenchymal-to-epithelial transitions
... tumor growth and progression through reduced post-transcriptional repression of FGF-2 and its receptor FGFR1, which act on both stromal and tumor cells to en- hance cancer cell survival, proliferation, and ...
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