GTP-Binding Proteins
Detection of Small GTP Binding Proteins Showing GTPase and GTP/ATP Binding Activities in the Ovary of the American Cockroach, Periplaneta Americana, during Oogenesis
... small GTP binding proteins involved in the regulatory mechanism of vitellogenin (Vg) endocytotic vesicles trafficking were detected, for the first time, in ovaries of the most basal hemimetabolus ...
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Glucose activates the carboxyl methylation of gamma subunits of trimeric GTP binding proteins in pancreatic beta cells Modulation in vivo by calcium, GTP, and pertussis toxin
... intracellular GTP stores ...these proteins. Presumably, calcium stim- ulates GTP binding to Cdc42, possi- bly via a GTP-exchange factor lead- ing to translocation of Cdc42 from cytosol ...
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Glucose and GTP dependent stimulation of the carboxyl methylation of CDC42 in rodent and human pancreatic islets and pure beta cells Evidence for an essential role of GTP binding proteins in nutrient induced insulin secretion
... if GTP alone can affect translocation of CDC42 indepen- dent of its effects on carboxyl methylation, islet or HIT cell homoge- nates were incubated in the presence of GTPgS (100 mM) and AFC (100 mM) in the absence ...
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Emerging Roles of Arf Like GTP Binding Proteins: From Membrane Trafficking to Cytoskeleton
... Arf proteins, including the Arls, have a conserved mode of membrane binding that distinguishes them from the other families of G ...membrane binding (Antonny et ...G proteins, the length of ...
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ICP4, the major regulatory protein of herpes simplex virus, shares features common to GTP-binding proteins and is adenylated and guanylated.
... We conclude from these experiments the following: i only a small set of proteins in isolated nuclei from infected and mock-infected HeLa cells is labeled by [_x-32P]GTP; ii the labeling [r] ...
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Components of neuronal calcium channels and their interaction with GTP-binding proteins
... the binding o f DHP antagonists to the inactivated state o f the channel, possibly by interaction o f the DHP with potential-sensitive structural components (Kokubun et a l 1986), thereby promoting stabilisation o ...
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Small GTP-binding proteins in the regulation of exocytosis in mast cells
... indicating that the maintenance o f a phosphorylated state is necessary for secretion to occur. Again, PKC has been im plicated in this process (Lillie et ah, 1991; H owell et ah, 1989). The loss o f responsiveness w as ...
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A potential role for guanine nucleotide binding protein in the regulation of endosomal proton transport
... The effects of guanosine 5'-triphosphate (GTP) and GTP-gamma-S, known activators of GTP binding proteins, on proton transport were investigated in endosome-enriched vesicles ...
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Involvement of a small GTP binding protein in HIV 1 release
... small GTP binding proteins in virus release, using specific bacterial ...small GTP binding proteins such as Cdc42, Rac, and/or Rho were ...
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Cell Polarity and Hyphal Morphogenesis Are Controlled by Multiple Rho-Protein Modules in the Filamentous Ascomycete Ashbya gossypii
... Small GTP-binding proteins of the Rho-family have been shown to be involved in the regulation of actin polarization as well as other ...Rho- proteins has not been studied so far in filamentous ...
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Alternative expression of platelet glycoprotein Ib(beta) mRNA from an adjacent 5' gene with an imperfect polyadenylation signal sequence
... We sought to investigate the origin of the longer transcript in CHRF-288–11 cells. Now we report a number of key differ- ences from the sequence reported by Kelly et al. (8) and in the fundamental conclusions derived ...
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Failure of hCG/LH receptors to stimulate the transmembrane effector adenylyl cyclase in human endometrium
... and GTP-binding proteins [(Gs, Gi1, 2, Gi3 and common sub-unit)] were determi- nated by immunoblot analysis as reported previously ...IL). Proteins were precipitated by adding ...
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Small GTP binding protein Rho mediated signaling promotes proliferation of rheumatoid synovial fibroblasts
... Rho is activated by the G12/13 family of heterotrimeric GTP-binding proteins through the stimulation of GEF activ- ity of p115RhoGEF [12,39]. However, p115RhoGEF can activate as well as inhibit Rho ...
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The GTPase domain of Galphao contributes to the functional interaction of Galphao with the promyelocytic leukemia zinc finger protein
... Heterotrimeric GTP-binding proteins (G proteins) mediate signal transduction and amplification in a variety of cell-signaling pathways ...for GTP in ...
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A Nucleotide Binding Motif in Hepatitis C Virus (HCV) NS4B Mediates HCV RNA Replication
... NBM-containing proteins (10, 11, 31, ...nucleotide binding (G, PM2, and B motif) are also ...of GTP-binding proteins (A) and selected viruses with the indicated NBM-containing protein ...
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Guanine nucleotide binding protein, alpha i 3, directly activates a cation channel in rat renal inner medullary collecting duct cells
... whether GTP binding proteins (G proteins) regulate sodium conducting channels in the apical membrane of renal inner medullary collecting duct (IMCD) cells and thereby modulate sodium ...
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Recent Advances in T Cell Signaling in Aging
... stress-associated protein kinases JNKs (c-jun amino terminal kinase), also known as SAPKs (stress-associated protein kinases) and the p38 cas- cade, demonstrates the diverse nature of the MAPK superfamily of enzymes ...
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The role of the cytoskeleton in malignant transformation
... Gene Activity Location of gene product Comments Type II: GTP binding proteins Ha-ras GTP-binding autokinase Plasma membrane inner face Normal homologue of Ha-ras and Ki-ras has Ki-ras GT[r] ...
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Antiviral Protein APOBEC3G Localizes to Ribonucleoprotein Complexes Found in P Bodies and Stress Granules
... myc-tagged proteins (YB-1, Hu antigen R [HuR], heterogeneous nuclear ribonucleoprotein [hnRNP] U, and Mov10) were constructed by cloning PCR products into pCMV3B, whereas vectors for the expression of C-terminally ...
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Brefeldin A Inhibits Cell-Free, De Novo Synthesis of Poliovirus
... nonhydrolyzable GTP analog) at 34°C for 20 min, followed by the normal dialysis step (see Materials and ...stable GTP analog which induces ARF membrane binding with a 10-fold-lower efficiency than ...
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