hardy-weinberg equilibrium
Extending Tests of Hardy–Weinberg Equilibrium to Structured Populations
... ABSTRACT Testing for Hardy–Weinberg equilibrium (HWE) is an important component in almost all analyses of population genetic data. Genetic markers that violate HWE are often treated as special cases; ...
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A k–Parameter Analysis of Hardy–Weinberg Equilibrium Conditions for the Mangrove Species in Two Islets of Eastern Visayas, Philippines
... The Hardy-Weinberg Equilibrium model was used as a platform for analyzing a field survey data on the distribution of mangrove species in two islets of Eastern Visayas, Tabuk and ...from ...
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Markers typed in genome wide analysis identify regions showing deviation from Hardy Weinberg equilibrium
... Background: Deviations from Hardy-Weinberg equilibrium (HWE) are commonly thought of as indicating genotyping errors, population stratification or some other artefact. However they could also arise ...
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Novel intron 2 polymorphism in the melanophilin gene is in Hardy Weinberg equilibrium and is not associated with coat color in goats
... Pigmentation plays important adaptation and physio- logical efficiency roles in animals. In the sequence of a 648 bp fragment representing intron 1, exon 2, and part of intron 2 of the MLPH mammalian pigmenta- tion gene, ...
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Testing for Hardy-Weinberg Equilibrium in Samples With Related Individuals
... HWE testing has lately regained serious attention from sponding likelihood-ratio test for unrelated individuals. human geneticists. Nielsen et al. (1999) proposed using However, these tests are not suitable for use in ...
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An Unconditional Exact Test for the Hardy-Weinberg Equilibrium Law: Sample-Space Ordering Using the Bayes Factor
... Much forensic inference based upon DNA evidence is made assuming that the Hardy-Weinberg equilib- rium (HWE) is valid for the genetic loci being used. Several statistical tests to detect and measure ...
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KCNA5 gene is not confirmed as a systemic sclerosis related pulmonary arterial hypertension genetic susceptibility factor
... HWE: Hardy-Weinberg equilibrium; K: potassium; KCNA5: potassium voltage- gated channel shaker-related subfamily member 5; Kv channels: potassium voltage-gated channels; lcSSc: limited cutaneous ...
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Hardy-Weinberg analysis of a large set of published association studies reveals genotyping error and a deficit of heterozygotes across multiple loci
... from Hardy – Weinberg equilibrium (HWD) can be due to recent admix- ture or selection at a locus, but is most commonly due to genotyping ...from Hardy – Weinberg equilibrium ...
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Genetic effects of rs3740199 polymorphism in ADAM12 gene on knee osteoarthritis: a meta-analysis
... respectively. Hardy–Weinberg equilibrium (HWE) was used to evaluate the deviation of data associated with the ADAM12 rs3740199 SNP in the control groups using χ 2 ...
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Original Article Correlation between interleukin-4 gene polymorphism and systemic lupus erythematosus and lupus nephritis
... Abstract: Systemic lupus erythematosus (SLE) is a common autoimmune connective tissue disease that may involve a variety of organ functions and seriously affects human health. We investigated interleukin-4 (IL-4) ...
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Screening of TNFα, IL 10 and TLR4 single nucleotide polymorphisms in individuals with asymptomatic and chronic cutaneous leishmaniasis in Colombia: a pilot study
... Abbreviations CCL: Chronic Cutaneous Leishmaniasis; CL: Cutaneous Leishmaniasis; HWE: Hardy-Weinberg Equilibrium; MAF: Minor Allele Frequency; MSR: Montenegro skin test reaction; RFLP: R[r] ...
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Analysis of in vitro ADCC and clinical response to trastuzumab: possible relevance of FcγRIIIA/FcγRIIA gene polymorphisms and HER 2 expression levels on breast cancer cell lines
... Abbreviations ADCC: antibody-dependent cellular cytotoxicity; BC: breast cancer; FcγR: FcγReceptor; E:T ratio: effector:target ratio; HWE: Hardy–Weinberg Equilibrium; mAb: monoclonal ant[r] ...
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The genomic complexity of a large inversion in great tits
... However, given the low frequency of the inversion, and assuming Hardy-Weinberg Equilibrium, we would expect less than two homozygous inverted birds and it is thus unclear whether the com[r] ...
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Modelling of the populating development of the genome in the radiation condition of the environment
... the Hardy-Weinberg genotype in the population, as well as conditions of complete elimination of the targeted allele by ionizing ra- ...Heterozygote; Hardy-Weinberg Equilibrium; ...
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Associations between three common single nucleotide polymorphisms (rs266729, rs2241766, and rs1501299) of ADIPOQ and cardiovascular disease: a meta-analysis
... A study included in this meta-analysis was based on the following criteria: 1) the study has sufficient data to allow association between CVD risk and ADIPOQ SNP to be assessed; 2) the study included original data (inde- ...
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Parkinson disease polygenic risk score is associated with Parkinson disease status and age at onset but not with alpha-synuclein cerebrospinal fluid levels
... Both the PPMI and WUSTL datasets are available by request from the PPMI website (www.ppmi-info.org) and the corresponding author of this manuscript respect- ively. Both populations were genotyped using the Illumina ...
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“HLA-G 3′UTR gene polymorphisms and rheumatic heart disease: a familial study among South Indian population”
... HWE: Hardy- Weinberg equilibrium; IDC: Idiopathic dilated cardiomyopathy; JIA: Juvenile idiopathic arthritis; LD: Linkage disequilibrium; MVL: Mitral valvular lesions; OR: Odds ratio; RA: Rheumatoid ...
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A systematic review of CD14 and toll-like receptors in relation to asthma in Caucasian children
... HWE: Hardy Weinberg Equilibrium, HPLC: High-Performance Liquid Chromatography, irt: in relation to, ISAAC: International Study of Asthma and Allergies in Childhood, ISS: Infant Immune Study, KOALA: ...
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First report of the Phe1534Cys kdr mutation in natural populations of Aedes albopictus from Brazil
... Abbreviations AS-PCR: Allelic specific PCR; HI: Infestation index; HW: Hardy-Weinberg equilibrium; Kdr: Knockdown resistance gene; LI: House-to-house larval survey; LIRAa: Rapid assessme[r] ...
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PubMedCentral-PMC5804232.pdf
... We next used the adegenet package (Jombart 2008; Jombart and Ahmed 2011) in R version 3.2.1 (R Core Team 2015) to assess the genetic population structure present among our different population groupings using ...
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