HBV RNA
Serum HBV RNA quantification: useful for monitoring natural history of chronic hepatitis B infection
... Although HBV RNA levels tend to decrease when progresses to HBeAg-negativity and inactivity, these levels increase if there is reactivation to active hepatitis, as shown in ...serum HBV RNA ...
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Peroxiredoxin 1, a Novel HBx-Interacting Protein, Interacts with Exosome Component 5 and Negatively Regulates Hepatitis B Virus (HBV) Propagation through Degradation of HBV RNA
... increased HBV RNA ...the RNA exosome complexes, is involved in Prdx1-mediated reduction of HBV RNA, we first examined the interaction between Prdx1 and Exosc5 in the presence or absence ...
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HBV RNA pre-genome encodes specific motifs that mediate interactions with the viral core protein that promote nucleocapsid assembly
... As HBV packages a pgRNA during assembly, we hypothesize that similar mechanistic constraints may contribute to formation of its ...NC. HBV RNA must be packaged in a manner that supports reverse ...
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Multiple Functions of Cellular FLIP Are Essential for Replication of Hepatitis B Virus
... on HBV replication and cccDNA level in HepG2-NTCP cells. HBV DNA levels were determined by Southern ...blotting. HBV RNA levels were analyzed by Northern blotting and real-time ...on ...
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Regulation of Hepatitis B Virus Replication by the Phosphatidylinositol 3-Kinase-Akt Signal Transduction Pathway
... inhibited HBV RNA tran- scription and consequently reduced HBV DNA replication in HepG2 ...of HBV gene transcription was apparently mediated by the activation of mTOR, as it was abolished by ...
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Hepatocyte Nuclear Factor 3β Inhibits Hepatitis B Virus Replication In Vivo
... of HBV transgenic ...3.5-kb HBV RNA protects a fragment of 327 nucleotides and the 2.4-kb HBV RNA protects a fragment of 226 ...L32 RNA protects a fragment of 101 nucleotides, ...
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Detection of Hepatitis B and C Viruses in Almost All Hepatocytes by Modified PCR Based In Situ Hybridization
... persistent HBV and HCV infection in the liver. HBV genomic DNA was detected in almost all hepatocytes, whereas HBV RNA or protein was differentially distributed only in a subset of the ...
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Inhibition of Hepatitis B Virus Gene Expression and Replication by Hepatocyte Nuclear Factor 6
... promotes HBV pgRNA decay in the ...Cellular RNA was extracted and analyzed for HBV ...of HBV pgRNA decay in the absence or presence of HNF6 ...of HBV RNA from each sample were ...
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Transcription of hepatitis B virus in peripheral blood mononuclear cells from persistently infected patients.
... its RNA transcripts in general (3, 5, 21, 39, ...of HBV in nonhepatocytes is incomplete, because it is difficult to distin- guish the four known mRNA species of HBV by conventional reverse ...
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Limited Hepatitis B Virus Replication Space in the Chronically Hepatitis C Virus-Infected Liver
... HCV RNA-positive hepatocytes in Ch1614 ...While HBV infection in positive-control animal ChAOA006 (Table 1) (8) spread to virtually all hepatocytes ...were HBV RNA positive ...⬃18% ...
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In Vitro Study of the Effects of Precore and Lamivudine-Resistant Mutations on Hepatitis B Virus Replication
... an HBV recombinant baculovirus containing more than one genome length of HBV DNA, the production of HBV proteins, transcripts, and intra- cellular and extracellular DNA is readily detected for 30 to ...
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Hepatitis B virus downregulates vitamin D receptor levels in hepatoma cell lines, thereby preventing vitamin D-dependent inhibition of viral transcription and production
... Methods: HBV transcription and replication was evaluated by qRT-PCR of the HBV-RNA and covalently closed circular DNA ...X HBV-Luc plasmid to the cells and measured the Luciferase activity ...
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Hepatitis B Virus RNA-Binding Proteins Associated with Cytokine-Induced Clearance of Viral RNA from the Liver of Transgenic Mice
... of HBV transgenic mice by a post- transcriptional mechanism that is triggered by the local production of gamma interferon (IFN- g ) and tumor necrosis factor alpha (TNF- a ) during intrahepatic inflammation ...
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Enhancement of Hepatitis B Virus Replication by Androgen and Its Receptor in Mice
... the HBV enhancer I element (13, ...in HBV replication in cell cultures ...this HBV ARE mutant ...putative HBV AREs in mediating the effect of androgen on HBV in ...of HBV ...
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Serum Hepatitis B Virus DNA, RNA, and HBsAg: Which Correlated Better with Intrahepatic Covalently Closed Circular DNA before and after Nucleos(t)ide Analogue Treatment?
... serum HBV RNA levels in patients with and without HBeAg loss during NUC ...serum HBV RNA levels between patients with and without HBeAg loss was observed only at week 96 ...whereas HBV ...
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Effect of dipterinyl calcium pentahydrate on hepatitis B virus replication in transgenic mice
... liver HBV DNA (PCR) was calculated for each mouse based upon the DCP-EM regression from Table 1, Table 2, rearranged algebrai- cally as shown in the legend of Figure ...liver HBV DNA (PCR) values ...
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Production of hepatitis delta virus and suppression of helper hepatitis B virus in a human hepatoma cell line.
... By transient transfection of the human hepatoma cell line HuH-7 with a plasmid, pA3HBV3.8, containing the 3.8-kb HBV DNA sequence, which is able to produce the pregenomic HBV RNA, we hav[r] ...
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MicroRNAs Associated With HBV Infection And HBV-related HCC
... repress HBV gene expression or rep- lication by directly targeting its gene ...in HBV transcripts that affect HBV replication, two dif- ferent procedures have been used in previous ...modulate ...
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The immunogenicity and safety of a reduced PRP content DTPw HBV/Hib vaccine when administered according to the accelerated EPI schedule
... HBV/Hib according to the 6-10-14 week EPI schedule. Blood samples were analysed prior to the first dose of study vaccine and one month after the third vaccine dose for the analysis of immune responses. Solicited ...
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Mammalian microRNA: an important modulator of host-pathogen interactions in human viral infections
... The miRNAs that directly bind to the 3′UTR of HIV-1 RNA (Fig. 2) include miR-28, miR-125b, miR-150, miR- 223 and miR-382, which are highly expressed in resting CD4+T cells [73]. Activation of resting CD4 + T-cells ...
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