healthy donor
Inferior vena cava diameters and collapsibility index changes reveal early volume depletion in a healthy donor model
... Methods: This was a prospective study, in which 29 people were enrolled. In each patient, a 6 seconds retrospective clip of each 9 abdomen anatomical division was recorded. In order to ensure adequate blinding, the clips ...
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Multiplex serum biomarker assessments: technical and biostatistical issues
... In this report, we detail reproducibility problems we encountered testing circulating cytokines, chemokines and growth factors by Luminex in serum samples which were stored over months to years under highly con- trolled ...
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Effective and cheap removal of leukocytes and platelets from Plasmodium vivax infected blood
... IRBC healthy donor blood was used for the initial side-by-side comparisons of leukocytes and platelet removal ...five healthy donors by ...each donor was divided into five two ml por- tions to ...
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In vivo behavior of neutrophils from two patients with distinct inherited leukocyte adhesion deficiency syndromes
... Flow cytometric analyses of surface expression of CD1 8, L-selectin, and sialyl-Lewisx sLex on neutrophils from a healthy donor control and two patients with leukocyte adhesion deficienc[r] ...
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Effects of Antibiotic Pretreatment of an Ulcerative Colitis-Derived Fecal Microbial Community on the Integration of Therapeutic Bacteria In Vitro
... One study that evaluated the use of antibiotics as a pretreatment for FMT in UC patients and included a relevant control arm was conducted by El-Nachef et al. and focused on the use of rifaximin (16). Rifaximin is a ...
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A novel anti-CD19 monoclonal antibody (GBR 401) with high killing activity against B cell malignancies
... the healthy donor PBMC de- pletion, SCID mice were sub-lethally irradiated at day 0, depleted for murine NK cells using the TMbeta-1 anti- body (mCD122 antigen, BioXCell, USA) on day 1 and 8, and injected ...
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A novel human STAT3 mutation presents with autoimmunity involving Th17 hyperactivation
... affect healthy donor Th17 cells, but in patient cell cultures the number of Th17 cells and the amount of IL-17 produced were decreased (Figure ...in healthy donors and the patient (Figure 2B), ...
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Exploring dendritic cell based vaccines targeting survivin for the treatment of head and neck cancer patients
... This argument of telomere erosion, however, surely does not hold for survivin specific T cells induced from PBMC taken from healthy donor blood (results shown in Figures 4, 5 and 6). Prior to in vitro ...
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Epigenomics of human embryonic stem cells and induced pluripotent stem cells: insights into pluripotency and implications for disease
... We envision that combining pluripotent cell differentia- tion models with epigenomic profiling will provide an important tool for uncovering the role of non-coding mutations in human disease. For example, if the disease ...
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Vaccinia virus-specific human CD4+ cytotoxic T-lymphocyte clones.
... b Clones established by UV-inactivated vaccinia virus stimulation of PBL from a healthy donor were tested for their ability to lyse uninfected or vaccinia virus-infected autologous B-LCL[r] ...
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Efficient ADCC killing of meningioma by avelumab and a high-affinity natural killer cell line, haNK
... streptomycin. Healthy donor PBMCs were obtained from the NIH Clinical Center Blood Bank (proto- col 99-CC-0618) and cryopreserved until ...cryopreserved healthy donor PBMCs using a negative ...
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Biosimilar G-CSF Based Mobilization of Peripheral Blood Hematopoietic Stem Cells for Autologous and Allogeneic Stem Cell Transplantation
... in healthy related donors and unrelated volunteer donors. As healthy donors gain no personal benefit from the procedure, absolute assurance of no harm to them is ...in healthy donors, suggested that ...
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Mesenchymal stromal cells from myelodysplastic and acute myeloid leukemia patients display in vitro reduced proliferative potential and similar capacity to support leukemia cell survival
... HD: Healthy donor; HD-MSC: MSC isolated from healthy donors; HSC: Hematopoietic stem cell; MCGS: Mesenchymal cell growth serum; MDS: Myelodysplastic syndrome; MDS-MSC: MSC isolated from ...
15
Fingolimod additionally acts as immunomodulator focused on the innate immune system beyond its prominent effects on lymphocyte recirculation
... of healthy controls were co- cultured with allogeneic naïve CD45RA + CD4+ T cells (1 × 10 5 cells/well) in the presence of LPS for 8 ...to healthy controls were co-cultured with naïve CD45RA+ CD4+ T cells ...
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Metabolic and scintigraphic studies of radioiodinated human C reactive protein in health and disease
... normal healthy donor and labeled with 125I, were undertaken in 8 healthy control subjects and 35 hospitalized patients including cases of rheumatoid arthritis, systemic lupus erythematosus, ...
8
Dido gene expression alterations are implicated in the induction of hematological myeloid neoplasms
... symptoms and signs suggested MDS/MPDs. Furthermore, 100% of human MDS/MPD patients analyzed showed Dido expression abnormalities, which we also found in other myeloid but not lymphoid neoplasms or in healthy ...
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Study of Association between Platelet Function and Anthropometry of Blood Donors in a Single Institution
... month. Donor with known cardiac problem, endocrinal disorder, thyroid disorder, diabetes (on insulin therapy), hypertension, subjects undergoing medication like non- steroidal anti-inflammatory drugs (NSAIDs), ...
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Detection of Francisella tularensis-Specific Antibodies in Patients with Tularemia by a Novel Competitive Enzyme-Linked Immunosorbent Assay
... Development of cELISA. Optimization of LPS concentration and dilution of antibodies were performed by checkerboard titra- tion (data not shown). The composition of blocking and dilution buffers and incubation times for ...
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Enzyme linked immunosorbent assay for immunoglobulin G subclass antibodies specific for enterobacterial Re core glycolipid in healthy individuals and in patients infected by gram negative bacteria
... Distribution of anti-CGL subclass activities in serum samples from 16 positive and 4 negative healthy blood donors Activity of the following Donor... activity of each subclass was not si[r] ...
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Functional characterization of rs2229094 (T>C) polymorphism in the tumor necrosis factor locus and lymphotoxin alpha expression in human retina: the Retina 4 project
... from healthy donors were obtained for RNA ...three healthy eyes from the eye tissue bank were fixed in formalin and embedded in paraf- fin for immunohistochemistry (IHC) ...
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