Heart morphogenesis
Activation of Notch1 signaling in cardiogenic mesoderm induces abnormal heart morphogenesis in mouse
... Notch signaling is implicated in many developmental processes. In our current study, we have employed a transgenic strategy to investigate the role of Notch signaling during cardiac development in the mouse. Cre ...
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Tbx5 and Tbx20 act synergistically to control vertebrate heart morphogenesis
... in heart development? Past studies of T-box genes have shown a direct link between members of the T-box gene family and cell ...two heart fields merge along the anterior midline, and that target specificity ...
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Eye and heart morphogenesis are dependent on melatonin signaling in chick embryos
... rudimentary heart morphogenesis was not hampered by luzindole but it was by 4-P-PDOT, which was not capable of impeding optic cup ...rudimentary heart was observed when compared with its ...
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Dishevelled associated activator of morphogenesis 1 (Daam1) is required for heart morphogenesis
... of morphogenesis 1 (Daam1), a member of the formin protein family, plays an important role in regulating the actin cytoskeleton via mediation of linear actin ...
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Dynamic Views of Structure and Function during Heart Morphogenesis
... of heart contractions and morphogenesis presents a number of imaging ...study heart morphogenesis and the effects of blood flow through the developing ...
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The fibronectin leucine rich repeat transmembrane protein Flrt2 is required in the epicardium to promote heart morphogenesis
... To investigate Flrt2 functional activities in vivo, we generated a null allele via gene targeting. Nearly all homozygous mutant embryos arrest at mid-gestation (E12.5) owing to cardiac insufficiency. Consistent with its ...
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Heart morphogenesis gene regulatory networks revealed by temporal expression analysis
... The heart is the earliest functioning organ in the developing embryo, and is essential for normal embryonic development and ...the heart forms as a linear tube located along the ventral midline of the ...
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Cited2 is required both for heart morphogenesis and establishment of the left right axis in mouse development
... indicated that specification of the left-right axis might not have occurred correctly in the Cited2-null embryos. To address this, we used the MLC3F- enhancer transgene that marks the right atrium (Franco et al., 2001; ...
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Left right asymmetry in heart development and disease: forming the right loop
... asymmetric heart morphogenesis in the mouse The efficient genetic tools available in the mouse model have been essential for dissecting the mechanisms and tracking specific cell populations underlying ...
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Heart and soul/PRKCi and nagie oko/Mpp5 regulate myocardial coherence and remodeling during cardiac morphogenesis
... during heart morphogenesis To test our hypothesis that Has/PRKCi regulates cardiac morphogenesis intrinsically within the myocardium, we generated a line of transgenic zebrafish that expresses ...
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Silencing the Morphogenesis of Rotavirus
... virus. However, it was surprising to find that the lipid envelope was not lost from the usually transient enveloped particles in the absence of VP7. VP4 and NSP4 have both been demon- strated to have ...
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Abrogation of tumor necrosis factor alpha converting enzyme inhibits embryonic lung morphogenesis in culture
... branching morphogenesis in ...branching morphogenesis in culture, whereas both scrambled and sense control oligonucleotides showed no adverse effects on lung ...lung morphogenesis in the presence of ...
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Morphogenesis of the lower incisor in the mouse from the bud to early bell stage
... dividing cells and the presence of few apoptosis in this condensed prospective inner dental epithelial cells were reminiscent of the secondary enamel knots at the future molar cusp tip regions (Jernvall et al., 1994; ...
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Hedgehog dependent proliferation drives modular growth during morphogenesis of a dermal bone
... Op morphogenesis is modular (Kimmel et ...edge morphogenesis is regulated independently from other facets of Op ...of morphogenesis: vp edge length and overall ventral ...
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Chick midgut morphogenesis
... ginning at E6, as soon as the first layer of circumferential muscle forms (Chevalier et al., 2017). The fact that aneural CAM cultured hindguts as well as explanted guts treated with the neurotoxin tetrodotoxin show ...
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Mouse odontogenesis in vitro: the cap stage mesenchyme controls individual molar crown morphogenesis
... vitro. Jowett and Ferguson (1991) suggested the existence of two phases of proliferation, the first being responsible for defining the tooth outline and cuspal pattern and the second for the increase in size to its final ...
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Morphogenesis, plasticity and irreversibility
... Here we discuss a constructive experiment to form a tissue from undifferentiated cells artificially. To be specific, we explain recent controlled tissue genera- tion by Asashima’s group (Ariizumi and Asashima 2001; Uochi ...
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Morphogenesis of Aura Virus
... 272 LASCANO, BERRIA, AND BARRERA ORO RESULTS The three developmental stages of group A arboviruses virus precursors, budding particles, and mature virus particles were found in thin sect[r] ...
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The morphogenesis of evolutionary developmental biology
... As with embryos, interactions early in the course of morpho- genesis have had a big impact on the discipline. In the early 1980s, John Bonner’s Evolution and Development (1982) and Raff and Kaufman’s Embryos, Genes, and ...
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Theoretical exploration of blastocyst morphogenesis
... about morphogenesis, it is found that there is a tendency for a curved frontier between the volumes from each 2-cell stage cell, the clonal volumes, to lie at an angle of ...
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