Helper T Cells
Proportions of circulating follicular helper T cells are reduced and correlate with memory B cells in HIV infected children
... CD4 T cells is the hallmark of HIV-induced immune dysfunction, the virus causes many other immunological abnormalities within the CD4 T-cell compart- ...CD4 T cells from HIV patients ...
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Selective induction of rheumatoid factors by superantigens and human helper T cells
... human helper T cells and co-cultured them with purified B ...cognate T-B cell interaction, we have used bacterial superantigens that function by cross-linking HLA molecules on the B cell with ...
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Helper T cells in flavivirus infection
... Recently the YF, West Nile dengue type 2 al., DEN2 encephalitis of yellow fever Rice et amino {SLE and virus genomes have been investigated 1985, 1986; Dalgarno et al., 1986a; amino-term[r] ...
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Changes in Follicular Helper T Cells in Idiopathic Thrombocytopenic Purpura Patients
... B cells, and antibody response ...TFH cells with ICOS and/or PD-1 expression can produce abundant IL-21 cytokine by itself, and the levels of both IL-21 and IL-6 are significantly associated with the fre- ...
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Effective antigen presentation to helper T cells by human eosinophils
... antigen-presenting cells to stimulate varied Th cell responses against a panel of antigens including HDM, TG or PPD, an ability that may help to determine the development of allergic ...
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The Sézary syndrome: a malignant proliferation of helper T cells
... malignant cells of thymus-derived (T)-cell ...as helper or suppressor cells regulating immunoglobulin synthesis by bone marrow-derived ...
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Follicular regulatory T cells inhibit the development of granzyme B–expressing follicular helper T cells
... TFR cells repress a cytotoxic gene program in TFH ...TFH cells were isolated by FACS, RNA was then prepared and subjected to ...TFH cells compared with WT TFH cells, and Gzmb is increased ...
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Disorders of B cells and helper T cells in the pathogenesis of the immunoglobulin deficiency of patients with ataxia telangiectasia
... mononuclear cells of 17 of the patients and 17 normal controls were cultured with pokeweed mitogen for 12 d and the immunoglobulin in the supernatants ...mononuclear cells from 9 of the 10 patients with a ...
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Interleukin-17 and type 17 helper T cells in cancer management and research
... These cells can mediate antitumoral effects by their ability to recruit immune effector cells (CTL, NK, DC) into the tumor bed and they can promote tumor growth by means of angiogenesis (pro- duction of ...
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Search for biomarkers of asbestos exposure and asbestos-induced cancers in investigations of the immunological effects of asbestos
... CD8+ cells, and NK ...of helper T cells should be investigated since the conversion and polarization of Treg and Th17 depends on the cytokine status surrounding these cells such as ...
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Capillary blood as an alternative specimen for enumeration of percentages of lymphocyte subsets
... of T-cells (CD3+), helper T-cells (CD4+), cytotoxic T-cells (CD8+), B-cells (CD19+), and NK-cells (CD56+) from both venous and capillary blood were highly ...
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Identification and manipulation of tumor associated macrophages in human cancers
... CD4+ helper T cells consti- tutes a powerful activation signal for antigen presenting ...following T-cell receptor mediated MHC class II- presented antigen ...CD4 T cell. Exposure of ...
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CXCR5+ T helper cells mediate protective immunity against tuberculosis
... non-hematopoietic cells is critical for early production of CXCL13 and immunity, but that both non-hematopoietic and hematopoietic sources of CXCL13 are required for long-term control of ...stromal cells ...
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Treatment with depleting CD4 monoclonal antibody results in a preferential loss of circulating naive T cells but does not affect IFN gamma secreting TH1 cells in humans
... CD45RA(neg)/R0(pos) T cells. Notably, within the CD45RA(pos) subset, T cells with phenotypic evidence of prior activation, ...Fas(neg) cells. Remarkably, while a decrease in the number ...
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CD27 expression discriminates porcine T helper cells with functionally distinct properties
... - T helper cells have functional similar- ities towards central (high proliferation capacity) and effector (rapid production of effector cytokines) memory T cells, respectively, as ...
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Lymphocyte subsets and their association with the severity of patients with major depressive disorder (mdd)
... of T helper cells (CD4 + T cells), T cytotoxic cells (CD8 + T cells), natural killer cells (CD16 ...
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T cell receptor independent immunosuppression induced by dexamethasone in murine T helper cells
... D10 cells to 3D3 stimulation was not affected by DEX, the costimulation provided by IL-1 was dramatically ...D10 cells were capable of proliferating, even in the presence of ...D10 cells remained ...
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Effects of pericytes and colon cancer stem cells in the tumor microenvironment
... of T cell function, which is considered the main factor responsible for response immune escape ...stromal cells can contribute to tumor microenvironment upregu- lates PD-L1 expression, by express GM-CSF and ...
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Differentiation of naive CD4+ T cells towards T helper 2 cells is not impaired in rheumatoid arthritis patients
... differentiated cells was analyzed upon ionomycin/phorbol myristate acetate stimulation for 6 hours in the presence of Brefeldin ...from cells of RA patients that produce IFN- γ but no IL-4 (Th1) and that ...
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Induction of rabies virus-specific T-helper cells by synthetic peptides that carry dominant T-helper cell epitopes of the viral ribonucleoprotein.
... To determine whether RNP-specific T-helper cells cross-reacted with the RNP or N protein from different rabies or rabies-related viruses, BALB/c mice were immunized with ERA BPL s.c., an[r] ...
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