Hematopoietic progenitor/stem cells
Decreased IRF8 expression found in aging hematopoietic progenitor/stem cells.
... human hematopoietic cells, we simultaneously examined IRF8 mRNA and protein expression in the PBCD34+ samples from 5 ...non-immortalized cells, and its protein expression significantly decreases in ...
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Lentivirus Gene Transfer in Murine Hematopoietic Progenitor Cells Is Compromised by a Delay in Proviral Integration and Results in Transduction Mosaicism and Heterogeneous Gene Expression in Progeny Cells
... Hematopoietic stem cells are an attractive target for gene therapy, as they can both self-renew and differentiate into all blood lineages, thus supporting hematopoiesis throughout the ...into ...
8
Neuropeptide Y regulates a vascular gateway for hematopoietic stem and progenitor cells
... by flow cytometry, taking advantage of the fact that N-terminal– cleaved SDF-1 3-68 has a 10-fold reduction in its binding efficiency to its receptor CXCR4 (22). As reported, CD26 cleaved full-length SDF-1 to SDF-1 3-68 ...
15
Small RNAs Play Big Roles in Hematopoietic Development
... in hematopoietic cells of myeloid origin have been largely ...in cells of the innate immune system, such as monocytes and macrophages, following exposure to inflammatory stimuli (O'Connell et ...
209
Arterial endothelium creates a permissive niche for expansion of human cord blood hematopoietic stem and progenitor cells
... muscle cells and perivascular mesenchyme, hematopoietic cells are in close vicinity of endothelial cells ...and hematopoietic cells de- velop in parallel ...endothelial ...
13
Circulating hematopoietic stem cell count is a valuable predictor of prematurity complications in preterm newborns
... circulating progenitor cells in respiratory system disorder found in neonates born ...+ progenitor cells compared to ...+ cells were correlated with a prolonged duration of mechanical ...
16
The homeobox gene CDX2 is aberrantly expressed in most cases of acute myeloid leukemia and promotes leukemogenesis
... epithelial cells in the ...leukemic cells of 90% of patients with acute myeloid leukemia (AML) but not in hematopoietic stem and progenitor cells derived from normal ...murine ...
13
Cusan, Monica (2012): Studie über das leukämogene Potential der Hoxb4-DeltaProlin Mutante in einem murinen Knochenmarkstransplantationsmodell und den Effekt der Hemmung von Histondeacetylasen in vitro und in vivo. Dissertation, LMU München: Medizinische Fakultät
... of cells with LTC-IC (long-term culture-initiating cells) activity, to promote the development of B cells in vivo, and to increase the number of cells able to repopulate NOD/SCID mice (Buske ...
171
Hematopoietic stem cells from peripheral blood the perspective of non mobilized peripheral blood
... vitro expansion. Results from pilot clinical trials of transplants using expanded UCB-HSC have shown no adverse effects in the patients. However, more clinical trials must be conducted using expanded HSC for guar- ...
9
Nutraceutical augmentation of circulating endothelial progenitor cells and hematopoietic stem cells in human subjects
... mononuclear cells (PBMC) were iso- lated by the Ficoll-Hypaque (Fisher Scientific, Ports- mouth NH) method ...collected. Cells were washed twice with RPMI 1640 medium containing 100 U/ml penicillin, 100 ...
10
Functional similarities of microRNAs across different types of tissue stem cells in aging
... tissue stem cells (TSCs) contribute to loss of tissue homeostasis, including re- ductions in lymphopoiesis and the long-term repopu- lating abilities of hematopoietic stem/progenitor ...
5
Open the gates: vascular neurocrine signaling mobilizes hematopoietic stem and progenitor cells
... of hematopoietic stem and progenitor cells (HSPCs) to mobilize from the bone marrow (BM) is essential for the treatment of patients with hematological malignancies or disorders who undergo ...
5
The role and potential of umbilical cord blood in an era of new therapies: a review
... of cells and to have regenerative potential for many clinical ...UCB-derived cells have become a popular ...UCB-derived cells and the great potential and current clinical applications of UCB in an ...
11
Enhanced self-renewal of hematopoietic stem/progenitor cells mediated by the stem cell gene Sall4
... on hematopoietic cell growth and progenitor ...BM cells were iso- lated and infected with Sall4- expressing ...4 cells were mixed with MethoCult ® medium and seeded in dishes for colony ...
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Vol 70, No 3 (2018)
... – hematopoietic stem cells; HSPC − hematopoietic stem/progenitor cells; HOXB4 – homeobox protein Hox-B4; TNC –total nucleated cells; CFU – colony forming unit; MSC ...
9
Characterization of Hemangioma-initiating Stem Cells
... All cells were plated at 20,000 cells/cm 2 density on 4- or 8-chambered slides for 48 hours prior to staining to allow for ...adherence. Cells were fixed with methanol and then stained for ...
98
Regulation of human hematopoietic stem cell lineage commitment
... My thesis projects focus on identifying and characterizing regulatory factors involved in myeloid commitment steps for human hematopoietic stem and progenitor cells (HSPCs), so as [r] ...
143
Activated fibronectin-secretory phenotype of mesenchymal stromal cells in pre-fibrotic myeloproliferative neoplasms
... stromal cells (BMSC) from patients with pre-fibrotic myeloproliferative neoplasms ...normal hematopoietic stem and progenitor cells and displayed increased matrix remodelling (in ...
5
Original Article Absence of myocyte regeneration by mobilization of bone marrow stem cells after myocardial infarction
... including hematopoietic and progenitor cells and endothelial progenitor cells (EPC) in bone marrow and peripheral blood ...+ stem cell in bone marrow and ...
6
Identification of molecules derived from human fibroblast feeder cells that support the proliferation of human embryonic stem cells
... from cells during passages 6-11 and 12-15, ...of stem cells, further supplemented with a large number of controls (in particular, for data ...
10