HEPATITIS B VIRUS REPLICATION
Hepatitis B Virus Replication and Release Are Independent of Core Lysine Ubiquitination
... 21. Kian Chua, P., M. H. Lin, and C. Shih. 2006. Potent inhibition of human hepatitis B virus replication by a host factor Vps4. Virology 354:1–6. 22. Kikonyogo, A., F. Bouamr, M. L. Vana, Y. ...
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Impact of hypoxia on hepatitis B virus replication
... 144 4.4 HBV producer cells and HIF stabilisation Having demonstrated that delivering HBV genomes into HepG2-NTCP cells stabilises HIF in a HBx independent manner, we wanted to confirm HIF stabilisation in cell lines ...
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Limited Hepatitis B Virus Replication Space in the Chronically Hepatitis C Virus-Infected Liver
... HBV replication, a comprehensive analysis of the ISG protein expression profile in HBV-negative and -positive cells would be required to identify the ISG protein expression profile that determines HBV resistance ...
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Posttranscriptional regulation of hepatitis B virus replication by the precore protein.
... promoter region have also been proposed to affect the repli- cation of HBV (33). In this regard, a modest increase in HBV replication (Fig. 2, lanes 3 and 7) was observed when HCC cells were transfected with an ...
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In Vivo Regulation of Hepatitis B Virus Replication by Peroxisome Proliferators
... viral replication intermediates is observed in the livers of these ...of replication intermediates in their livers, treatment with per- oxisome proliferators results in similar levels of replication ...
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High-level hepatitis B virus replication in transgenic mice.
... 1995 Hepatitis B virus (HBV) transgenic mice whose hepatocytes replicate the virus at levels comparable to that in the infected livers of patients with chronic hepatitis have been ...
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Efficient inhibition of hepatitis B virus replication by hepatitis delta virus ribozymes delivered by targeting retrovirus
... pose, those based on retroviruses are the best understood and the most widely used [13,14]. The genomes of the viral vectors integrate stably into the host cell DNA, thereby allowing long-term expression of the inserted ...
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Interleukin-12 inhibits hepatitis B virus replication in transgenic mice.
... Members of the transgenic mouse lineage used in this study FIG. 1. IL-12-induced inhibition of hepatic HBV replication. Three groups of four HBV transgenic mice were injected intraperitoneally with 1, 10, or 100 ...
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Inhibition of Hepatitis B Virus Replication by the Interferon-Inducible MxA Protein
... MxA protein does not interact with the HBV nucleocapsid. It has recently been demonstrated that MxA interacts with the nucleocapsid of THOV and prevents transport of the nucleo- capsid into the nucleus. Our aim was to ...
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Enhancement of Hepatitis B Virus Replication by Androgen and Its Receptor in Mice
... These mutations were previously shown to abolish the binding of the AR to the two AREs. The 1.3-mer HBV genomes with and without these ARE mutations were first transfected into Huh7 hepatoma cells for an analysis of ...
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Inhibition of Hepatitis B Virus Replication by Interferon Requires Proteasome Activity†
... Relatively little is known about the cellular factors that are necessary for the IFN-induced inhibition of HBV replication. The results presented here indicate that proteasome activity is required for this ...
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A Highly Attenuated Vesicular Stomatitis Virus-Based Vaccine Platform Controls Hepatitis B Virus Replication in Mouse Models of Hepatitis B
... tenuated virus displayed markedly reduced pathogenesis but induced similar MHBs- specific CD8 ⫹ T cell and antibody ...HBV replication in animals that were later chal- lenged by hydrodynamic injection or ...
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Spontaneous reactivation of hepatitis B virus replication in an HIV coinfected patient with isolated anti Hepatitis B core antibodies
... the hepatitis flare in this patient could be interpreted as a ...HBV replication by the immune surveillance and/or due to the detection escape mutation that may occurred early in the chronic ...
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MicroRNA 130a Regulates both Hepatitis C Virus and Hepatitis B Virus Replication through a Central Metabolic Pathway
... ABSTRACT Hepatitis C virus (HCV) infection has been shown to regulate microRNA 130a (miR-130a) in patient biopsy specimens and in cultured ...and hepatitis B virus (HBV) ...HCV ...
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MicroRNA 130a Regulates both Hepatitis C Virus and Hepatitis B Virus Replication through a Central Metabolic Pathway
... ABSTRACT Hepatitis C virus (HCV) infection has been shown to regulate microRNA 130a (miR-130a) in patient biopsy specimens and in cultured ...and hepatitis B virus (HBV) ...HCV ...
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Hepatocyte Nuclear Factor 3β Inhibits Hepatitis B Virus Replication In Vivo
... and replication observed in cell culture can be recapitulated in vivo in the HBV transgenic mouse model ...viral replication-competent genomes suggests HNF3 may reduce viral transcription by interfering ...
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Duck Hepatitis B Virus Replication in Primary Bile Duct Epithelial Cells
... This study is the first to report on the characterization of primary culture of duck intrahepatic biliary cells and the de novo synthesis of DHBV proteins and replicative intermedi- ates. Only CAM 5.2 staining cell ...
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Hepatitis B Virus Replication Induces Methylation of both Host and Viral DNA
... viral replication is a major therapeutic goal to reduce morbidity and mortality from chronic hepatitis B virus (HBV) ...viral replication. However, virus-induced overex- pression ...
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Enhancement of Hepatitis B Virus Replication by the Regulatory X Protein In Vitro and In Vivo
... 3.2-kb hepatitis B virus (HBV) genome encodes a single regulatory protein termed ...in virus replication remains ...plasmid-based replication assay with the hydrodynamic tail ...
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Interleukin-18 Inhibits Hepatitis B Virus Replication in the Livers of Transgenic Mice
... IL-18 inhibits HBV replication: time course. To examine the kinetics and duration of the antiviral effect of IL-18, groups of three transgenic mice from lineage 1.3.32 were injected sub- cutaneously with 10 g of ...
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