Her 2 neu
HER 2 therapy HER 2/neu diagnostics in breast cancer
... circulating HER-2/neu ...serum HER-2/neu test reported that all individuals tested, both normal (male and female) and cancer patients, had some level of circulating serum ...
11
Expression and prognostic significance of E Cadherin, EGFR, p53 and HER-2/NEU in Gastric Carcinoma.
... showed HER-2/Neu over expression showed T3 level of infiltration, no association with HER- 2/Neu expression and survival was ...
166
HER-2/neu Marker Examination using Immunohistochemical Method in Patients Suffering from Gastric Adenocarcinoma
... of HER-2/neu marker was examined by immunohistochemical staining by Envision method using Hercep Test Kit (Dako, Denmark) according to manufacture's ...of HER-2/neu was used ...
5
Role of microvessel density, HER-2/ NEU expression and CD-34 in prognostication and grading of bladder carcinomas.
... Of the total 101 transitional cell carcinomas, 50 cases of varying grade and stage were selected in a random manner and subjected to immunohistochemical analysis with a panel of 2 markers – CD 34 and ...
140
HER-2/neu gene analysis on endoscopic biopsy samples and gastric resection materials in gastric carcinomas
... Our HER-2/neu positivity rate was determined as ...between HER-2/neu overexpression and gene amplification in resection materials was ...for HER-2/neu ...
7
Antiangiogenesis immunotherapy induces epitope spreading to Her-2/neu resulting in breast tumor immunoediting
... of Her-2/neu in stretches of 500–800 bp each (EC1 [AA 20–326], EC2 [AA 303–501], EC3 [AA 479–655], IC1 [AA 690–1081], IC2 [AA 1020– 1260]) as was described ...
12
Hypoxia-mediated alterations and their role in the HER-2/neu- regulated CREB status and localization
... A role for CREB in the development of tumors has been suggested since it is often overexpressed and more active in many solid and hematopoietic tumors [23-26]. This could be influenced by the modulation of signalling ...
24
Original Article Association between hormone receptors and HER-2/neu is age-related
... that consider the disease as a single entity [6]. This single estimate does not convey age-relat- ed variation in breast cancer risks. One clini- cally important example is that hormone recep- tors do not predict the ...
8
Nonredundant roles of antibody, cytokines, and perforin in the eradication of established Her 2/neu carcinomas
... On the other hand, the enhanced TAA cross-presen- tation that takes place in the presence of antibodies (17), as well as the binding of anti-TAA antibodies to the Fcγ receptors (FcγRs) on APC surfaces (18), may result in ...
11
Triple-negative (ER, PgR, HER-2/neu) breast cancer in Indian women
... Abstract: The aim of our study was to analyze triple-negative (TN) breast cancer, which is defined as being negative for the estrogen receptor (ER), the progesterone receptor (PgR), and the human epidermal growth factor ...
11
HER 2/Neu Status in Gastric Carcinomas in a Series of Egyptian Patients and Its Relation to Ki 67 Expression
... Objective: HER-2/neu status in gastric carcinomas (GCs) has not been studied before in the Egyp- tian ...of HER-2/neu and Ki-67 using immunohistochemistry ...score 2+ ...
13
Exposure to depleted uranium does not alter the co expression of HER 2/neu and p53 in breast cancer patients
... biological changes may occur that reduce the requirement for continued biomarker signaling. It is also possible that, when gene alterations occur in breast cancer, high prolif- eration rates are found irrespective of the ...
8
C myc, not HER 2/neu, can predict recurrence and mortality of patients with node negative breast cancer
... and HER-2/ neu were examined with regard to their ability to predict DFS, OS and rate of recurrence, as well as ...and HER-2/neu amplification in ...of ...
7
Original Article Evaluation of p16 and HER-2/neu expression in Adenocarcinoma of uterine cervix- A study from tertiary health care center
... Background: Cervical cancer is the most common cancer in women worldwide with current knowledge showing rising trends of adenocarcinoma over Squamous cell carcinoma. They are more aggressive with relatively worse ...
7
Association between HER-2/neu over-expression and clinico-pathologic parameters of breast cancer in northern Malaysia
... of HER-2/neu with oestrogen ...and HER- 2/neu do not response to tamoxifen treatment due to interaction of tyrosine kinase pathway with hormonal pathway ...
5
Concordant morphologic and gene expression data show that a vaccine halts HER 2/neu preneoplastic lesions
... the HER-2/neu oncogene and inhibits their proliferation as well as their production of VEGF, while activating their production of the antian- giogenic monokines IP-10 and MIG ...about 2 months ...
10
The impact of nottinghem prognostic index (NPI) on the occurrence of relapses in her 2 / NEU positive breast cancer
... of HER-2 / neu, as it was expected, and this parameter reflects the importance of prediction of recurrent disease in HER-2 / neu positive breast cancer as it is described in our ...
5
Tumor suppressor genes promote rhabdomyosarcoma progression in p53 heterozygous, HER-2/neu transgenic mice
... of HER-2/neu produced rhabdomyosarcomas exclusively in the proximal urethra; Fos knockout lead to periorbital tumors [29]; Ras activation to tumors predominantly on the limbs ...and ...
12
Unraveling the role of preexisting immunity in prostate cancer patients vaccinated with a HER-2/neu hybrid peptide
... preexisting) and during vaccinations, T cell responses (measured as % of dextramer-specific CD8 + T cells) against other HER-2/neu epitopes or against epitopes from other tumor antigens, representing ...
15
Prevalence of HER-2/ neu receptor amplification and its effects over prognosis of the patients with breast cancer
... A total of 120 operated patients with biopsy proven breast carcinoma were included in this study. Information from the patients was collected after taking informed consent from patient, spouse or guardian. The data ...
5