Herpes Simplex Virus 1 and 2
Inhibition of Curcumin Treated Herpes Simplex Virus 1 and 2 in Vero Cells
... curcumin-treated Herpes simplex virus-1 (HSV-1) and Herpes simplex virus-2 (HSV-2) virions in cultured Vero ...
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Heptad Repeat 2 in Herpes Simplex Virus 1 gH Interacts with Heptad Repeat 1 and Is Critical for Virus Entry and Fusion
... Herpes simplex virus 1 (HSV-1) entry into cells and cell-cell fusion mediated by HSV-1 glycoproteins require four glycoproteins, gD, gB, gH, ...class 1 fusion ...
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Structure Based Mutations in the Herpes Simplex Virus 1 Glycoprotein B Ectodomain Arm Impart a Slow Entry Phenotype
... 3A virus cell penetration is partially rescued at higher ...and virus cell penetration by favoring a prefusion conformation of the protein, the addition of heat might serve to rescue the fusion defect (29, ...
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Herpes simplex virus 1 UL41 protein abrogates the antiviral activity of hZAP by degrading its mRNA
... UL41-null virus R2621 exerts no such function, which leads us to wonder whether hZAP could inhibit R2621 ...of 1. At 2 h post-infection, the cells were treated or mock treated with tetracycline (1000 ...
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Pangaea and the Out-of-Africa Model of Varicella-Zoster Virus Evolution and Phylogeography
... cella virus is Old World simian varicella virus ...FIG 2 Phylogenetic tree for the family ...HSV-1, herpes simplex virus 1; HSV-2, herpes ...
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The Fusion Loops of the Initial Prefusion Conformation of Herpes Simplex Virus 1 Fusion Protein Point Toward the Membrane
... mixed 2:1 with a suspension of bovine serum albumin (BSA)-coated 10-nm colloidal gold particles (Aurion, Wageningen, The Netherlands) that served as fiducial markers, and 4- l drops were then applied to ...
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Role of Herpes Simplex Virus 1 γ34.5 in the Regulation of IRF3 Signaling
... ) and peaked around 6 hpi (data not shown). Both Us11 and ICP34.5, which contribute to countering translational arrest, are present in the tegument (44). Despite this, we speculate that de novo ICP34.5 is required for ...
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Expression of Herpes Simplex Virus 1-Encoded MicroRNAs in Human Trigeminal Ganglia and Their Relation to Local T-Cell Infiltrates
... Herpes simplex type 1 (HSV-1) is a neurotropic virus which establishes lifelong latency in human trigeminal ganglia ...varicella-zoster virus could be ...
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Herpes Simplex Virus 1 Tegument Protein UL46 Inhibits TANK Binding Kinase 1 Mediated Signaling
... UL46 associates with TBK1 and inhibits activation of TBK1. Previous studies showed that homodimerization and phosphorylation of TBK1 are required for its activation (16–18). The activated TBK1 phosphorylates IRF3 and ...
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Quantitation of herpes simplex virus type 1 DNA and latency-associated transcripts in rabbit trigeminal ganglia demonstrates a stable reservoir of viral nucleic acids during latency.
... but not for those containing 2 pg of DNA. Thus, by definition, 4 pg of TG DNA represents one copy of the rabbit genome. Since one genome copy represents one-half of a cell’s chromo- somes, 8 pg of TG DNA must ...
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Fine structure analysis of type-specific and type-common antigenic sites of herpes simplex virus glycoprotein D.
... A region common to herpes simplex virus type 1 and 2 gD amino acid residues 11 to 19 and two sites specific for herpes simplex virus type 2 gD one determined by proline at position 7, th[r] ...
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A Gene Capable of Blocking Apoptosis Can Substitute for the Herpes Simplex Virus Type 1 Latency-Associated Transcript Gene and Restore Wild-Type Reactivation Levels
... wild-type virus and marker-rescued dLAT2903R is ...detected 2-kb LAT (solid rectangle) appears to be an intron derived by splicing of the primary LAT ...This virus is missing key promoter elements, ...
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Characterization of herpes simplex virus type 2 transcription during latent infection of mouse trigeminal ganglia.
... RNA from an immediate early region of the type 1 herpes simplex virus genome is present in the trigeminal ganglia of latently infected mice.. Latent herpes simplex virus type 1 transcrip[r] ...
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Interaction of herpes simplex virus glycoprotein gC with mammalian cell surface molecules.
... plus 2-nitriloacetic acid agarose resin (Qiagen) for possible use in ...polyhedrosis virus) by using Baculogold (Pharmingen) as the source of baculovirus DNA ...
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Herpes simplex virus infects most cell types in vitro: clues to its success
... Paired immunoglobulin-like type 2 receptor- a (PILR a ) PILR is one of the paired receptor families. It is expressed mainly in immune cells where one receptor in the family has activating function, while another ...
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Effect of Apolipoprotein E on the Cerebral Load of Latent Herpes Simplex Virus Type 1 DNA
... demonstrated, herpes simplex virus type 1 (HSV-1) has recently been implicated in the patho- genesis of this disease (22, 25, ...(1, 2). One of the impor- tant features of ...
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Extracellular vesicles during Herpes Simplex Virus type 1 infection: an inquire
... fragment 1; BGLF5: BamHI G leftward frame 5; BHRF1: BamHI fragment H rightward open reading frame 1; BNLF2a: BamHI-N leftward frame 2a; BZLF1: BamHI Z fragment leftward open reading frame 1; CCR5: ...
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A Pre-Immediate-Early Role for Tegument ICP0 in the Proteasome-Dependent Entry of Herpes Simplex Virus
... Reduced capsid transport to the nucleus in the absence of tegument ICP0. To begin to address the impact of virion ICP0 on HSV entry, we analyzed HSVs bearing mutations in the ICP0 gene (Table 1). Viruses with ICP0 ...
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The Herpes Simplex Virus 2 Virion-Associated Ribonuclease vhs Interferes with Stress Granule Formation
... pseudorabies virus Us3 as bait, eIF4A (a core SG component), ribonucleoprotein L (an mRNA binding protein), and ribosomal protein S26 (a com- ponent of the small ribosomal subunit) were all identified as po- ...
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Amplification of Reiterated Sequences of Herpes Simplex Virus Type 1 (HSV 1) Genome To Discriminate between Clinical HSV 1 Isolates
... To test the stabilities of ReI, ReIII, ReIV, and ReVII, PCR amplification of these regions was performed with 24 separate subclones of HSV-1 F, and the sequences of these regions were compared with those of the ...
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