heterogeneous nuclear ribonucleoprotein
Heterogeneous Nuclear Ribonucleoprotein A1 Binds to the 3′-Untranslated Region and Mediates Potential 5′-3′-End Cross Talks of Mouse Hepatitis Virus RNA
... The 3 ⴕ -untranslated region (3 ⴕ -UTR) of mouse hepatitis virus (MHV) RNA regulates the replication of and transcription from the viral RNA. Several host cell proteins have previously been shown to interact with this ...
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Purification and partial sequencing of the nuclear autoantigen RA33 shows that it is indistinguishable from the A2 protein of the heterogeneous nuclear ribonucleoprotein complex
... chromatography on heparin-Sepharose and by chromatofocusing. Sequence analysis of five tryptic peptides revealed that their sequences matched corresponding sequences of the A2 protein of the heterogeneous ...
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Polypyrimidine tract-binding protein and heterogeneous nuclear ribonucleoprotein A1 bind to human T-cell leukemia virus type 2 RNA regulatory elements.
... HeLa nuclear proteins UV cross-linked to CRS RNAs with murine monoclonal antibodies, we now show that p40CRS is heterogeneous nuclear ribonucleoprotein (hnRNP) A1 and p60CRS is polypyrimidine ...
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Mutational analysis of a heterogeneous nuclear ribonucleoprotein A2 response element for RNA trafficking
... The heterogeneous nuclear ribonucleoprotein (hnRNP) A2 response element (A2RE) is a 21-nucleotide segment of the myelin basic protein mRNA that is necessary and sufficient for cytoplasmic transport ...
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Regulation of Notch Signaling by the Heterogeneous Nuclear Ribonucleoprotein Hrp48 and Deltex in Drosophila melanogaster
... In an effort to identify the interactors of Dx involved in the regulation of the Notch pathway, we carried out a protein– protein interaction screen based on immunoprecipitation followed by a mass spectrometry (MS) ...
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Specific Interaction of Heterogeneous Nuclear Ribonucleoprotein Particle U with the Leader RNA Sequence of Vesicular Stomatitis Virus
... using nuclear extract, it was found that in addition to the previously reported La protein, a 120-kDa nuclear protein specifically interacts with the leader ...as heterogeneous nuclear ...
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Heterogeneous Nuclear Ribonucleoprotein A2 Participates in the Replication of Japanese Encephalitis Virus through an Interaction with Viral Proteins and RNA
... identified heterogeneous nuclear ribonucleoprotein A2 (hnRNP A2) as a binding partner of the JEV core protein by pulldown purification and mass ...
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Heterogeneous Nuclear Ribonucleoprotein L Interacts with the 3′ Border of the Internal Ribosomal Entry Site of Hepatitis C Virus
... Translation initiation of hepatitis C virus (HCV) RNA occurs by internal entry of a ribosome into the 5 * nontranslated region in a cap-independent manner. The HCV RNA sequence from about nucleotide 40 up to the N ...
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The spliceosomal autoantigen heterogeneous nuclear ribonucleoprotein A2 (hnRNP A2) is a major T cell autoantigen in patients with systemic lupus erythematosus
... to nuclear antigens, including autoantibodies directed to the heterogeneous nuclear ribonucleoprotein A2 (hnRNP-A2), which occur in 20% to 30% of SLE patients as well as in animal models of ...
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Translational upregulation of folate receptors is mediated by homocysteine via RNA heterogeneous nuclear ribonucleoprotein E1 interactions
... cells exhibited biochemical evidence of folate deficien- cy and FRs were markedly upregulated ninefold. How- ever, the FR mRNA was disproportionately low (being increased by only twofold), suggesting that upregula- tion ...
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Nuclear heterogeneous nuclear ribonucleoprotein D is associated with poor prognosis and interactome analysis reveals its novel binding partners in oral cancer
... (AUF1)/heterogeneous nuclear ribonucleoprotein D (hnRNPD) is an ARE-binding pro- tein which regulates the mRNA stability of many genes involved in cell cycle, proliferation, survival, senescence and ...
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A Novel Heterogeneous Nuclear Ribonucleoprotein-Like Protein Interacts with NS1 of the Minute Virus of Mice
... encoded proteins and since NS1 is a large, multifunctional protein, it seemed reasonable to assume that it functions in concert with host cell proteins. Furthermore, the highly puri- fied NS1 appears to lose some of its ...
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Novel Role of Heterogeneous Nuclear Ribonucleoprotein E1 in Regulation of Apoptosis and Autophagy by a Triazole Derivative in Vascular Endothelial Cells
... Recent years, using small chemical molecules to modulate biological phenomenon and reveal insights into diverse biological questions has made significant influence on various areas of development biology and cell biology ...
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Heterogeneous Nuclear Ribonucleoprotein K Supports Vesicular Stomatitis Virus Replication by Regulating Cell Survival and Cellular Gene Expression
... The heterogeneous nuclear ribonucleoprotein K (hnRNP K) is a member of the family of hnRNPs and was recently shown in a genome-wide small interfering RNA (siRNA) screen to support vesicular ...
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Heterogeneous nuclear ribonucleoprotein K (hnRNP K) is a tissue biomarker for detection of early Hepatocellular carcinoma in patients with cirrhosis
... as heterogeneous nuclear ribonucleoprotein K (hnRNP K) (homo sapiens, P61978) by mass spectrometry (Table 2), and selected for further validation in a separate ...
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Functional Interaction of Heterogeneous Nuclear Ribonucleoprotein C with Poliovirus RNA Synthesis Initiation Complexes
... this nuclear RNA-binding protein relocalizes to the cytoplasm due to alterations in nucleocytoplasmic trafficking (9, 22, ...of nuclear proteins, may be an es- sential part of the picornavirus replicative ...
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Identification and cloning of a novel heterogeneous nuclear ribonucleoprotein C-like protein that functions as a transcriptional activator of the hepatitis B virus enhancer II.
... The cDNA clone of the protein, designated E2BP, was isolated from a Agtll expression library constructed from the hepatoma cell line HuH-6 which was screened with a binding site probe de[r] ...
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SYNCRIP, a Member of the Heterogeneous Nuclear Ribonucleoprotein Family, Is Involved in Mouse Hepatitis Virus RNA Synthesis
... SYNCRIP represents yet another factor in MHV RNA syn- thesis. The one-step RNA affinity purification used in this study was highly specific, since we were able to detect PTB and hnRNP A1 with positive- and ...
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Anti A2/RA33 autoantibodies are directed to the RNA binding region of the A2 protein of the heterogeneous nuclear ribonucleoprotein complex Differential epitope recognition in rheumatoid arthritis, systemic lupus erythematosus, and mixed connective tissue disease
... the heterogeneous nuclear RNP (hnRNP) complex ...small nuclear ribonucleoprotein (U1-snRNP) or the Sm proteins, are typically targeted by patients with SLE and MCTD, but not by patients with ...
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Heterogeneous Nuclear Ribonucleoprotein M Facilitates Enterovirus Infection
... the heterogeneous nu- clear ribonucleoprotein M (hnRNP M), a nucleocytoplasmic shuttling RNA-binding protein that is primarily known for its role in pre-mRNA ...
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