Histone h4
The NuA4 acetyltransferase and histone H4 acetylation promote replication recovery after topoisomerase I-poisoning
... for histone H4 acetylation, play an important role in DNA repair in conjunction with other histone modifications that serve as signals to recruit these ...nucleosomal H4 at four lysine ...
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A Viral Histone H4 Joins to Eukaryotic Nucleosomes and Alters Host Gene Expression
... A viral histone H4 (CpBV-H4) has been identified from a polydnavirus (PDV) called Cotesia plutellae bracovirus (CpBV) (4–6). PDVs are symbiotic to some hymenopteran insect species and help a ...
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Histone H4 acetylation regulates behavioral inter individual variability in zebrafish
... complex, histone H4 acetylation changes, and lar- val behavioral inter-individual ...the histone H4 acetylation changes observed in ChIP- seq were maintained at the gene expression ...to ...
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The FACT Histone Chaperone Guides Histone H4 Into Its Nucleosomal Conformation in Saccharomyces cerevisiae
... cerevisiae histone/nucleosome chaperone Facilitates Chromatin Transactions (FACT), causing defects in both transcription and DNA ...describe histone mutations that suppress some of these defects, providing ...
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PIWI homologs mediate Histone H4 mRNA localization to planarian chromatoid bodies
... that histone mRNA levels increase in Smedwi-1;-3 knockdowns, which correlates with a decrease in histone mRNA localization to chromatoid bodies, could be explained by a model in which these RNP granules ...
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The conformational flexibility of the C-terminus of histone H4 promotes histone octamer and nucleosome stability and yeast viability
... also H4 are required for Asf1 histone chaperone function ...of H4 forms an antiparallel β sheet with the globular core of ...that H4 adopts in the nucleosome [3], requires a nearly 180 ° ...
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Histone H4 Facilitates the Proteolysis of the Budding Yeast CENP-ACse4 Centromeric Histone Variant
... of histone variants into nucleosomes can alter chromatin-based ...the histone H3 variant found exclusively at centromeres that serves as an epigenetic mark for centromere identity and is required for ...
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Global Replication-Independent Histone H4 Exchange in Budding Yeast
... in either the wild type or the cac2 ⌬ , hir1 ⌬ , or asf1 ⌬ strain (Fig. 4D and data not shown). These results demonstrate that the FIG. 2. Altering the expression of H4HA does not change the relative distribution of its ...
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A novel DNA/histone H4 peptide complex detects autoantibodies in systemic lupus erythematosus sera
... Combined with clinical and serological data, this assay can contribute to a correct diagnosis and staging of SLE patients. The high specificity of this test allows the differen- tial diagnosis of SLE from other ...
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Identification of repressive and active epigenetic marks and nuclear bodies in Entamoeba histolytica
... of histone H4 are subject to acetylation and/or methylation, where in the nucleus these epigenetic marks are located, and what roles they play in the nuclear archi- ...against histone H4. Our ...
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Establishment of Murine Cytomegalovirus Latency In Vivo Is Associated with Changes in Histone Modifications and Recruitment of Transcriptional Repressors to the Major Immediate-Early Promoter
... against histone H3, histone H4, acetylated histone H3 (Ac-H3), or acetylated histone H4 (Ac-H4), followed by quantitative real-time PCR with primers/probe specific to  ...
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Modulation of the functional association between the HIV 1 intasome and the nucleosome by histone amino terminal tails
... each histone tail in the IN/MN binding, we next performed pull-down experiments with MNs assembled using octamers lacking the tails of either H4, H3, H2A or ...the histone tails had a larger impact ...
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A novel route to product specificity in the Suv4-20 family of histone H4K20 methyltransferases
... lack histone H4 methylation and lacks a Suv4-20 homolog, the H4K20me1 mark has now been identified, and this may point to an as yet unidentified H4K20 monomethylase family in yeast ...
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Journal of Applied Pharmaceutical Science
... The experimental design of our study is relevant and very close to organ-specific mechanisms, as we attempted to maintain the in vivo architecture and intercellular communication by culturing lung tissue pieces. The ...
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Association with the origin recognition complex suggests a novel role for histone acetyltransferase Hat1p/Hat2p
... on histone H4, an epigenetic mark which precedes DNA replication and which is rapidly removed after incorporation into DNA, is highly conserved throughout eukaryotic evolu- tion ...for histone ...
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The Bromodomain and Extra-Terminal Domain (BET) Family: Functional Anatomy of BET Paralogous Proteins
... YFP- histone H4, but is not observed in cells transfected with both CFP-Brd2 and YFP- histone ...on H4 histone effectively abolish the FRET ...with H4 tail peptides, either ...
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Differential patterns of histone acetylation in inflammatory bowel diseases
... specific histone acetylation and deacetylation have been associated in more recent years with a number of different functions such as nucleosome assembly, het- erochromatin silencing, transcription and gene ...
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Histone deacetylases 1 and 2 maintain S-phase chromatin and DNA replication fork progression
... on histone H4 K5 and K12 residues prior to their deposition onto nascent chromatin, and are then removed during chromatin matur- ation ...these histone deposition ...the histone deposition ...
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Identification and Characterization of the Genes Encoding the Core Histones and Histone Variants of Neurospora crassa
... and H4 (hH3 and hH4-1), we identified a second histone H4 gene (hH4-2), a divergently transcribed pair of genes that encode H2A and H2B (hH2A and hH2B), a homolog of the F/Z family of H2A variants ...
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Systematic genetic and proteomic screens during gametogenesis identify H2BK34 methylation as an evolutionary conserved meiotic mark
... [5–10]. Histone PTMs are an essential regulatory element of spermatogenic chroma- tin ...of histone H4 (H4K44ac) during meiosis promotes chromatin accessibility during homol- ogous recombination ...
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