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HIV 1

Phosphorylation of HIV 1 Tat by CDK2 in HIV 1 transcription

Phosphorylation of HIV 1 Tat by CDK2 in HIV 1 transcription

... type 1 (HIV-1) requires host cell factors for all steps of the viral replica- tion ...all HIV-1 accessory proteins, including Vpu [3], Vpr [4], Vif [5], Nef [6], and Rev ...of ...

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Kinase Control of Latent HIV-1 Infection: PIM-1 Kinase as a Major Contributor to HIV-1 Reactivation

Kinase Control of Latent HIV-1 Infection: PIM-1 Kinase as a Major Contributor to HIV-1 Reactivation

... The same considerations hold for a possible effect of PIMi IV on components of the paused RNAP II machinery at the latent LTR and its transition into active elongation following stimula- tion. RNAP II complex formation, ...

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Impact of the HIV 1 genetic background and HIV 1 population size on the evolution of raltegravir resistance

Impact of the HIV 1 genetic background and HIV 1 population size on the evolution of raltegravir resistance

... HIV-1 RNA initially decreased after start of raltegravir con- taining cART (2.2 log decrease in HIV-1 RNA), but the viral load rebounded quickly after therapy initiation (< 81 days, Fig. ...

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Drug resistance in HIV-1

Drug resistance in HIV-1

... only HIV-1 P o l sequences rather than full-length HIV-1 genomes being retained in the vector, re-arrangement within transformed ...as HIV-1 LTR sequences (Peden, 1992; Bi and ...

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Primary Human Immunodeficiency Virus Type 1 (HIV-1) Infection during HIV-1 Gag Vaccination

Primary Human Immunodeficiency Virus Type 1 (HIV-1) Infection during HIV-1 Gag Vaccination

... subsequent HIV-1 ...became HIV-1 infected ap- proximately a year after finishing four vaccinations over 6 months ...progressing HIV-1 infection, which the authors hypothesized ...

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Field Evaluation of a Rapid Human Immunodeficiency Virus (HIV) Serial Serologic Testing Algorithm for Diagnosis and Differentiation of HIV Type 1 (HIV 1), HIV 2, and Dual HIV 1 HIV 2 Infections in West African Pregnant Women

Field Evaluation of a Rapid Human Immunodeficiency Virus (HIV) Serial Serologic Testing Algorithm for Diagnosis and Differentiation of HIV Type 1 (HIV 1), HIV 2, and Dual HIV 1 HIV 2 Infections in West African Pregnant Women

... of HIV type 1 (HIV-1) non-B subtypes poses another diagnos- tic ...both HIV-1 and HIV-2 infections exist in West ...of HIV-1 and HIV-2 infections and ...

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Cytopathic Mechanisms of HIV 1

Cytopathic Mechanisms of HIV 1

... of HIV, primarily macrophages and T ...of HIV-1 has shown some structural and functional similarities to the hydrophobic internal region of bovine prion protein (BPrP tm ) ...length HIV The ...

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HIV 1 assembly in macrophages

HIV 1 assembly in macrophages

... in HIV-1-infected macrophages represent endocytosed particles produced by neighboring cells ...hypothesis: 1) Immuno-EM profiles obtained by several teams show viral particles at various stages of ...

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HIV 1 Nef: at the crossroads

HIV 1 Nef: at the crossroads

... of HIV-1 transmission to his wife are not available [13] to explain how she came to be infected with the double deleted Nef just ...whose HIV-1 infections have been extensively ...oped ...

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HIV 1 integrase modulates the interaction of the HIV 1 cellular cofactor LEDGF/p75 with chromatin

HIV 1 integrase modulates the interaction of the HIV 1 cellular cofactor LEDGF/p75 with chromatin

... its HIV-1 cofactor activity in the absence of other het- erologous chromatin binding domains is still controver- sial ...rescue HIV-1 infection exhibiting approximately 50% of the ...

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Revisiting HIV 1 uncoating

Revisiting HIV 1 uncoating

... of HIV-1 uncoating - its tim- ing, location and mechanism - are by no means resolved, recent work enables us to etch a possible model for the early steps of HIV-1 ...of HIV-1 ...

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The Replicative Fitness of Primary Human Immunodeficiency Virus Type 1 (HIV-1) Group M, HIV-1 Group O, and HIV-2 Isolates

The Replicative Fitness of Primary Human Immunodeficiency Virus Type 1 (HIV-1) Group M, HIV-1 Group O, and HIV-2 Isolates

... of HIV-1 group M over HIV-2 and group O in western Africa ...(Fig. 1) may be related more to transmission efficiency than pathogenesis in the ...58). HIV-1 can then be ...

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The HIV 1 transmission bottleneck

The HIV 1 transmission bottleneck

... significant limitations to each of these approaches. The bulk PCR-based approaches are compromised by introduction of Taq polymerase-based errors due to lack of proof reading capability of the enzyme leading to ...

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HSV 2  and HIV 1  permissive cell lines co infected by HSV 2 and HIV 1 co replicate HSV 2 and HIV 1 without production of HSV 2/HIV 1 pseudotype particles

HSV 2 and HIV 1 permissive cell lines co infected by HSV 2 and HIV 1 co replicate HSV 2 and HIV 1 without production of HSV 2/HIV 1 pseudotype particles

... by HIV-1NDK strain were superin- fected by HSV-1 or HSV-2 at a multiplicity of infection (MOI) of ...or 1 pfu/cell for 72 ...of HIV- 1 RNA, and that HIV-1 did not ...

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Alkylating HIV-1 Nef - a potential way of HIV intervention

Alkylating HIV-1 Nef - a potential way of HIV intervention

... against HIV-1 by altering Nef conformation as shown by the CD spec- trum change ...anti HIV-1 activity due to technical ...anti HIV-1 ...

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Dynamics of HIV 1 mRNA expression in patients with long term nonprogressive HIV 1 infection

Dynamics of HIV 1 mRNA expression in patients with long term nonprogressive HIV 1 infection

... of HIV-1 proviral DNA and of the reference single-copy b -globin gene in DNA samples, while the in vitro transcription product from plas- mid pSPLI-II was used for the RT-PCR quantification of ...

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Differential Ability of Primary HIV-1 Nef Isolates To Downregulate HIV-1 Entry Receptors

Differential Ability of Primary HIV-1 Nef Isolates To Downregulate HIV-1 Entry Receptors

... of HIV-in- fected cells, and this leads to promotion of viral replication through superinfection resistance and other ...laboratory HIV-1 ...to HIV-1 ...

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Importin α3 Interacts with HIV-1 Integrase and Contributes to HIV-1 Nuclear Import and Replication

Importin α3 Interacts with HIV-1 Integrase and Contributes to HIV-1 Nuclear Import and Replication

... during HIV nuclear import (1, 2, 6, 10, 16, 20), we first used an in vitro pulldown assay to test for an interaction between HIV IN and Imp ␣ ...whether HIV IN could bind directly to Imp ␣ 3 ...

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Identification of Acute HIV 1 Infection by Hologic Aptima HIV 1 RNA Qualitative Assay

Identification of Acute HIV 1 Infection by Hologic Aptima HIV 1 RNA Qualitative Assay

... low HIV-1 RNA-concentration speci- mens ...30 HIV-1 RNA copies/ml (32); thus, dilution of low concentration specimens would not be expected to compromise ...Quantitative HIV-1 ...

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Multiple HIV 1/M + HIV 1/O dual infections and new HIV 1/MO inter group recombinant forms detected in Cameroon

Multiple HIV 1/M + HIV 1/O dual infections and new HIV 1/MO inter group recombinant forms detected in Cameroon

... of HIV in Cameroon is becoming more complex; this is not surprising due to the wide genetic diversity of viruses cir- culating in this region, but the situation is maybe even more ...of HIV-1/M or/O ...

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