HIV-1 Gag
Human Endogenous Retrovirus K Gag Coassembles with HIV-1 Gag and Reduces the Release Efficiency and Infectivity of HIV-1
... HERV-K Gag/PTAP(ⴚ) is rescued by HIV-1 Gag ...whether HIV-1 Gag interacts with HERV-K Gag in cells, we examined the impact of HIV-1 Gag ...
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Solution Properties of Murine Leukemia Virus Gag Protein: Differences from HIV-1 Gag
... MLV Gag, mutants, and chimeras (see ...(Stratagene). HIV-1 Gag protein was purified using phosphocellulose chro- matography as described earlier (11, ...MLV Gag proteins and chimeras ...
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HIV 1 Gag Blocks Selenite Induced Stress Granule Assembly by Altering the mRNA Cap Binding Complex
... that HIV-1 Gag associated with the 5= cap potentially through a spe- cific interaction with eIF4E as shown by coimmunoprecipitation and in situ PLA ...of HIV-1 ...with 1, ...and ...
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Proteomic analysis of HIV 1 Gag interacting partners using proximity dependent biotinylation
... different HIV-1 proteins (Additional file 1: Table S1). HIV-1 MA domain of Gag has been previously shown to interact with pro- teins involved in translation such as the putative ...
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Differential control of CXCR4 and CD4 downregulation by HIV 1 Gag
... other HIV-1 proteins, Nef and Env, have been shown to interact with or regulate ...an HIV-1 infected ...that HIV-1 Nef induces downregulation of CXCR4 from the cell surface of ...
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The Cellular Protein Lyric Interacts with HIV-1 Gag
... a Gag variant lacking the basic NC residues required for RNA ...GFP-fused Gag were either left untreated or treated with RNase. Gag was subsequently immunoprecipitated with anti- GFP ...a Gag ...
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Primary Human Immunodeficiency Virus Type 1 (HIV-1) Infection during HIV-1 Gag Vaccination
... an HIV-1 Gag DNA vaccine, and was acutely infected with HIV-1 during the vaccination ...Merck HIV-1 gag DNA vaccine/AlPO 4 vaccine (a DNA vector containing ...
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Abrogation of contaminating RNA activity in HIV 1 Gag VLPs
... the gag-containing pFastBac™ Dual construct under the polyhedrin (PH) promoter (Figure ...of 1 × sterile Dulbecco ’ s phosphate buffered saline (PBS, Sigma ® ) and incubated with ...
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Efavirenz Enhances HIV-1 Gag Processing at the Plasma Membrane through Gag-Pol Dimerization
... cytoplasmic Gag processing, we carried out con- focal ...of Gag/Gag- Pol ...derivative Gag- FLAG/Pol-HA, which allows discrimination between Gag and Gag-Pol by addition of two ...
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Binding of human immunodeficiency virus type 1 (HIV-1) RNA to recombinant HIV-1 gag polyprotein.
... The gag polyprotein is cleaved into the mature viral proteins by the viral protease at the time of particle budding 71, but it is probably the gag precursor polyprotein and not any of it[r] ...
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HIV 1 Gag C terminal amino acid substitutions emerging under selective pressure of protease inhibitors in patient populations infected with different HIV 1 subtypes
... full-length gag nucleotide sequences was largely lacking, our third analysis aimed to evaluate whether these 93 Gag variants were significantly associated with genotypic PI ...the gag and the ...
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Mechanistic Differences between Nucleic Acid Chaperone Activities of the Gag Proteins of Rous Sarcoma Virus and Human Immunodeficiency Virus Type 1 Are Attributed to the MA Domain
... the Gag polyprotein is responsible for annealing primer tRNAs to the PBS to initiate reverse transcription in retroviruses, but only HIV-1 Gag chaperone activity has been demonstrated in ...
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Particle Size Determinants in the Human Immunodeficiency Virus Type 1 Gag Protein
... of Gag that control the size of a retroviral ...of Gag consisting of CA plus the spacer peptides located between CA and ...of HIV-1, mutants that have a linker insertion within spacer peptide ...
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Virus-Specific Cytotoxic T Lymphocytes in Human Immunodeficiency Virus Type 1-Infected Chimpanzees
... and HIV epitopes defined in infected humans were also recognized by CTL found in virus-infected ...whether HIV-1 CTL epitopes are also shared between HIV-1-infected humans and ...
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Vpu Augments the Initial Burst Phase of HIV-1 Propagation and Downregulates BST2 and CD4 in Humanized Mice
... deficient HIV-1-infected mice were predominantly higher than those in plasma and BM, suggesting that the spleen is a major site for viral ...WT HIV-1-infected mice was similar to that of ...
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Analysis of Human Immunodeficiency Virus Type 1 Gag Dimerization-Induced Assembly
... precursor Gag (PrGag) proteins play an essential role in virus ...type 1 (HIV-1) Gag protein assembly in vitro, we analyzed the assembly properties of Gag proteins in which NC ...
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Ubiquitin conjugation to Gag is essential for ESCRT mediated HIV 1 budding
... the HIV-1 Gag protein and eliminating the PTAP motif or the ability of TSG101 to bind Gag reduces viral release by ...lanes 1, 3 and ...
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Monitoring HIV-1 Assembly in Living Cells: Insight from Dynamic and Single Molecule Microscopy
... immature HIV-1 Gag assembly (see Figure 2 for illustration). HIV-1 Gag was one of the first proteins to be visualized by super resolution PALM microscopy [44] showing different ...
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Human immunodeficiency virus type 2 (HIV 2) Gag is trafficked in an AP 3 and AP 5 dependent manner
... HIV-1 Gag has previously been reported to interact with the clathrin adaptor proteins AP-1 [16], AP-2 [17] and AP-3 ...to HIV-1 particle release [17]. AP-1 and -3, ...
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Tetherin Inhibits Nipah Virus but Not Ebola Virus Replication in Fruit Bat Cells
... for Gag, human tetherin or the indicated tetherin orthologues, and tetherin antagonist (Vpu, ...of Gag-derived VLPs in culture supernatants and Gag expression in WCLs was analyzed by ...of Gag ...
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