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Host factor associated with HIV disease progression

Overweight/Obesity and HIV Disease Progression in HIV+ Adults in Botswana

Overweight/Obesity and HIV Disease Progression in HIV+ Adults in Botswana

... 19 rs1781749, LEP (leptin) rs10954174, LEP rs6966536, and MCAR (melanocortin 4 receptor) rs17782313 the effect size for the FTO SNP was 2.2, p=0.007. This finding was adjusted for age, sex and sex-specific pubertal age. ...

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Predictors of disease progression in HIV infection: a review

Predictors of disease progression in HIV infection: a review

... of HIV-specific cytotoxic lymphocyte responses and cell-surface CD38 expression correlate significantly with the control of viral ...and disease progression remains ...is associated with poor ...

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Host factors influencing susceptibility to HIV infection and AIDS progression

Host factors influencing susceptibility to HIV infection and AIDS progression

... of disease can be grouped into three categories: 1) viral factors determining the replicative properties of the virus or its ability to escape immune responses; 2) cellular factors modulating the innate or ...

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HIV 1 subtype C envelope characteristics associated with divergent rates of chronic disease progression

HIV 1 subtype C envelope characteristics associated with divergent rates of chronic disease progression

... Secondly, an N to S change at codon 671, which is within a linear epitope- N WFNIT- that is recognized by nAb 4E10, may result in a loss of this recognition site. In addition, this codon was positively selected for in ...

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HIV infection  induced posttranslational modification of T cell signaling molecules associated with disease progression

HIV infection induced posttranslational modification of T cell signaling molecules associated with disease progression

... the HIV infection induced T cell unresponsiveness, we studied signal-trans- ducing molecules proximal to the T cell receptor (TCR) in T lymphocytes of HIV-infected ...of HIV infected patients since B ...

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KIR3DS1/L1 and HLA Bw4 80I are associated with HIV disease progression among HIV typical progressors and long term nonprogressors

KIR3DS1/L1 and HLA Bw4 80I are associated with HIV disease progression among HIV typical progressors and long term nonprogressors

... to HIV viral ...to HIV disease progression; the LTNP group was com- posed of 40 individuals who had no history of antiretro- viral therapy and maintained CD4 + T cell counts above 500 cells/μl ...

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Inflammatory Markers Associated With Disease Progression of Cardiorenal Syndrome

Inflammatory Markers Associated With Disease Progression of Cardiorenal Syndrome

... Another potential source for error was the reliance on self-reported information, which may lead to bias. Again, in order to address this limitation, objective, examination information was used. While the NHANES dataset ...

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High Frequencies of Polyfunctional CD8+ NK Cells in Chronic HIV-1 Infection Are Associated with Slower Disease Progression

High Frequencies of Polyfunctional CD8+ NK Cells in Chronic HIV-1 Infection Are Associated with Slower Disease Progression

... to HIV-1 immune control, nongenetic NK cell parameters directly associated with slower disease progression have not been defined ...untreated HIV-infected subjects, we show that higher ...

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The serologic decoy receptor 3 (DcR3) levels are associated with slower disease progression in HIV-1/AIDS patients

The serologic decoy receptor 3 (DcR3) levels are associated with slower disease progression in HIV-1/AIDS patients

... in HIV-1/AIDS patients and assessed the association of sDcR3 and the disease progression of HIV-1 ...in HIV-1 patients infected with subtype B may slow down the rate of disease ...

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Antihelminthics in helminth-endemic areas: effects on HIV disease progression

Antihelminthics in helminth-endemic areas: effects on HIV disease progression

... Only one trial reported how adverse events were monitored, using patient record-keeping cards and house visits (Kelly 1996 ZMB). Despite these biases, most randomized controlled trials (RCTs) reported no adverse events ...

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Virological and Immunological Factors Associated with HIV-1 Differential Disease Progression in HLA-B*58:01-Positive Individuals

Virological and Immunological Factors Associated with HIV-1 Differential Disease Progression in HLA-B*58:01-Positive Individuals

... protective HIV allele. However, not all B*58:01-expressing persons exhibit slow HIV disease ...HLA-B*58:01-positive, HIV subtype C-infected individuals for up to 31 months from the onset of ...

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Virological and Immunological Factors Associated with HIV-1 Differential Disease Progression in HLA-B*58:01-Positive Individuals

Virological and Immunological Factors Associated with HIV-1 Differential Disease Progression in HLA-B*58:01-Positive Individuals

... protective HIV allele. However, not all B*58:01-expressing persons exhibit slow HIV disease ...HLA-B*58:01-positive, HIV subtype C-infected individuals for up to 31 months from the onset of ...

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Decreased DACH1 expression in glomerulopathy is associated with disease progression and severity

Decreased DACH1 expression in glomerulopathy is associated with disease progression and severity

... DNA damage [38]. Accordingly, we speculate that the DACH1 may contribute to DNA repair by inhibit podocyte proliferation at G 1 /S and G 2 /M phases. However, this study had some limitations, such as lack of multivariate ...

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Cerebrospinal fluid lactate is associated with multiple sclerosis disease progression

Cerebrospinal fluid lactate is associated with multiple sclerosis disease progression

... prognostic factor of MS severity; it may thus represent a possible confounding factor limiting the significance of our ...of disease severity measured up to 5 years later, indicating that energy ...

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Role of common human TRIM5α variants in HIV 1 disease progression

Role of common human TRIM5α variants in HIV 1 disease progression

... restriction factor tripartite motif protein (TRIM)5 α , is characterized by marked amino acid diversity among primates, including specific clusters of residues under positive ...to HIV-1 infection, or the ...

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Predicting the Impact of CD8+ T Cell Polyfunctionality on HIV Disease Progression

Predicting the Impact of CD8+ T Cell Polyfunctionality on HIV Disease Progression

... in HIV research why polyfunctional CD8 ⴙ T cell responses are associated with better viral control, while individual functional correlates of protection have not been identified so ...in HIV-1 infec- ...

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Effect of low dose corticosteroids in HIV disease progression: systematic review

Effect of low dose corticosteroids in HIV disease progression: systematic review

... activation associated with HIV disease progression and found significantly lower bio-markers levels in patients receiving prednisolone compared to untreated patients, suggesting that ...

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Nerve Growth Factor Pathobiology During The Progression Of Alzheimer\u27s Disease

Nerve Growth Factor Pathobiology During The Progression Of Alzheimer\u27s Disease

... the progression of ...is associated with an imbalance between TrkA-mediated survival signaling and proNGF/p75 NTR -mediated pro-apoptotic ...the disease (Mufson et ...the progression of AD, ...

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The combination of CXCL9, CXCL10 and CXCL11 levels during primary HIV infection predicts HIV disease progression

The combination of CXCL9, CXCL10 and CXCL11 levels during primary HIV infection predicts HIV disease progression

... rapid HIV disease progression ...exact HIV infection time and obtaining plasma samples from patients with PHI are ...54 HIV-infected patients with well-documented dates of infection and ...

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Role of viral evolutionary rate in HIV 1 disease progression in a linked cohort

Role of viral evolutionary rate in HIV 1 disease progression in a linked cohort

... of HIV-1 from the donor A, the 2 recipients B and C gradually deterio- rated over a 15-year period to low CD4 + /CD8 + T cell counts and high viral loads despite the continuation of HAART since ...and host ...

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