HPMC K100M
Design and Evaluation of Zolpidem Tartrate Matrix Tablets for Extended Release Using Natural Gums and HPMC K100M
... The present research work was successful in improving the efficacy of zolpidem tartrate oral therapy as the drug release was extended for twelve hours thus reducing dosing frequency thereby improving patient compliance. ...
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PREPARATION AND INVITRO EVALUATION OF SOLID DISPERSION OF PIROXICAM WITH HPMC K100M BY USING SPRAY DRYING TECHNIQUE
... of HPMC K100M in 1600– 1700 cm -1 assigned to the carbonyl stretching ...the HPMC polymer, the carbonyl group is more favorable in hydrogen bonding over the tertiary amine because of the steric ...
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ROLE OF HYDROPHILIC POLYMERS ON GASTRO RETENTIVE FLOATING DRUG DELIVERY SYSTEMS OF FAMCICLOVIR
... Famciclovir, HPMC K4M, HPMC K15M and HPMC K100M and physical mixtures of Famciclovir with these polymers were obtained, which showed all the characteristic peaks of Famciclovir and polymers ...
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Formulation and evaluation of controlled release matrix tablet of Albuterol sulphate
... A sustained release matrix formulation for Albuterol Sulphate was designed and developed to achieve a 12 h release profile. Using HPMC K15M and HPMC K100M as an inert matrix forming agent to control ...
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Journal of Applied Pharmaceutical Science
... The low bioavailability (15%) and good solubility of Domperidone Maleate in acidic pH following oral administration favours development of a gastro retentive formulation. Gastroretentive floating matrix tablets of ...
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FORMULATION AND EVALUATION OF EXTENDED RELEASE TABLETS OF DARIFENACIN HYDROBROMIDE
... using HPMC K4M CR and HPMC K 100M CR, as polymers at different ...of HPMC K4M CR & 5 % of HPMC K100M CR was found to be the optimized formulation based on in- vitro release of drug ...
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“Design and Evaluation of Extended Release Tablets of Pramipexole dihydrochloride monohydrate” by S. S. S. Rakesh, S. Anbazhagan,M.V. Basaveswara Rao, Joginapalli Sreekanth, India.
... Pramipexole dihydrochloride monohydrate was procured from MSN labs Hyd, HPMC K4M, HPMC K15M and HPMC K100M were provided as a gift sample by colorcon. Povidone sample was procured from ISP ...
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Effect of polymers and gas forming agents on gastro-retentive floating tablets of acyclovir
... Acyclovir was a gift sample from Biodeal Laboratories Pvt. Ltd, Surendranagar, Gujarat. HPMC K4M & HPMC K100M was provided by Colorcon Asia Pvt. Ltd. PVP K30 was purchased from Himedia Lab. Pvt. ...
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FORMULATION AND EVALUATION OF FLOATING TABLETS OF GABAPENTIN
... DSC analysis measures the amount of energy absorbed or released by a sample when it is heated or cooled, providing quantitative and qualitative data on endothermic (heat absorption) and exothermic (heat evolution) ...
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FORMULATION AND IN VITRO EVALUATION OF EFFERVESCENT FLOATING DRUG DELIVERY SYSTEM OF CIPROFLOXACIN TABLET
... The effervescent floating tablets of ciprofloxacin were formulated in six different batches F1 to F6 by using hydrophilic polymers HPMC K100M, and HPMC E15 with effervescing agent sodium bicarbonate, ...
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FORMULATION AND EVALUATION OF FLOATING MATRIX TABLETS OF TAPENTADOL HCLK. Venkateswara Reddy*, Shimoga Nagaraj Sriharsha and S. Sujatha DOWNLOAD/VIEW/http://doi.org/10.5281/zenodo.220872
... evaluate HPMC K100M, HPMC K15M and carbopol 934P as matrix formers in this design of floating tablets of tapentadol, a poorly water soluble ...(i) HPMC K100M (ii) HPMC K15M and ...
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Effect of different polymers on release of the sustained release tablets of the glipizide
... like HPMC – K100M, HPMC – K15M, Chitosan, and Aloe mucilage on release of the sustained release tablets of the ...the HPMC – K100M shows the better retarding of drug release from the ...
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Development of Sustained Release Floating Tablet for Cefpodoxime Proxetil (CP)
... statistically analyzed by Student t-test and ANOVA using GraphPad Prism software. The results concluded that persistent and stable buoyancy was obtained by gas trapping by the hydration of high viscosity grade ...
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FORMULATION AND EVALUATION OF ONCE DAILY MATRIX TABLETS OF METOPROLOL SUCCINATE USING HYDROXYPROPYL METHYL CELLULOSE BY WET GRANULATION TECHNIQUE
... CONCLUSION: Controlled release following Higuchi kinetics attained in the current study indicates that the matrix tablet of metoprolol succinate prepared using HPMC K100M and ethyl cellulose solution can ...
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FORMULATION DEVELOPMENT AND CHARACTERIZATION OF ATAZANAVIR SULPHATE CONTROLLED RELEASE NON-EFFERVESCENT FLOATING MATRIX TABLETS
... ATZ sulfate was received as a gift sample from Aurobindo Pharma Ltd, Hyderabad, India. Hydroxypropyl methylcellulose (HPMC K100M) procured from DOW chemical company, USA. Ethylcellulose (EC) purchased from ...
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Formulation and evaluation of domperidone maleate bilayer tablet
... Preliminary trial batches of domperidone maleate sustained release bilayer tablet was successfully prepared and developed using various polymer such as HPMC K100M, Metolose and superdisintegrant such as ...
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FORMULATION AND EVALUATION OF FLOATING MATRIX TABLETS OF CIPROFLOXACIN
... Ciprofloxacin received as a gift sample from Sripathi Labs Ltd, Hyderabad. The polymers HPMC K4 and HPMC K100M were received as a gift sample from DOW chemical company, USA. Magnesium stearate was ...
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FORMULATION AND EVALUATION OF METFORMIN HYDROCHLORIDE SUSTAINED RELEASE TABLETS USING POLYELECTROLYTE COMPLEXES
... The present study involves formulation and evaluation of sustained release tablets of metformin hydrochloride which is BCS Class-III drug, using polyelectrolyte complexes of gum karaya-chitosan. Formulations were ...
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Formulation and Evaluation of GRDDS of Gatifloxacin
... In vitro dissolution studies for all the formulations (F1- F12) were studied. All the formulations showed sustained release but the formulation which contained drug and HPMC K100M (90 mg) (F3) showed ...
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EFFECT OF PROCESSING AND POLYMER VARIABLES ON INVITRO RELEASE OF METOPROLOL SUCCINATE EXTENDED RELEASE TABLETS
... In this study, an extended release tablet formulation of Metoprolol succinate was developed. The effect of different polymers hydrophilic (HPMC K100M, CMC Na) as well as hydrophobic (Eudragit L30 D55) on ...
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