human beta-defensin
Original Article Human beta-defensin 2 promotes the proliferation of lung cancer cells through ATP-binding cassette transporter G2
... the human innate defensive system, the respiratory epi- thelium participates in the immunity by produc- ing various bioactive ...materials. Human beta- defensin 2 (hBD2) is an important member ...
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De Novo sphingolipid synthesis is essential for Salmonella-induced autophagy and human beta-defensin 2 expression in intestinal epithelial cells
... Background: Sphingolipids are important for innate immune response to eliminate infected pathogens and involved in autophagy. On the other hand, nucleotide‑binding oligomerization domain‑containing protein 2 (NOD2) ...
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Original Article Inhibitory effect of recombinant human beta-defensin-2 on angiogenesis and inflammatory factors of rat model of endometriosis
... Background: Human β defensin-2 is one of the important members of defensin family in endogenous antibiotic peptides, which plays an important role in immune defense ...recombinant human ...
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Human beta-defensin 3 contributes to the carcinogenesis of cervical cancer via activation of NF-κB signaling
... Human beta-defensin 3 (hBD3), an antimicrobial peptide (AMP) expressed in epithelium in response to various stimulations including human papillomavirus infection, has recently been found to be ...
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Human beta defensin 1: an antimicrobial peptide of urogenital tissues
... of human b -defensin-1 ...a human actin probe (Clontech, Palo Alto, ...with human mRNA from spleen, thymus, prostate, testis, ovary, small intestine, colon, peripheral blood leukocyte, heart, ...
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Human beta defensin 2 is a salt sensitive peptide antibiotic expressed in human lung
... Additional studies were performed to determine if hBD-2 peptide is secreted onto the airway surface. Human lungs were derived from potential donor organs that were deemed unsuit- able after harvest. Lungs were ...
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Identification of a cell-penetrating peptide domain from human beta-defensin 3 and characterization of its anti-inflammatory activity
... Abstract: Human beta-defensins (hBDs) are crucial factors of intrinsic immunity that function in the immunologic response to a variety of invading enveloped viruses, bacteria, and ...
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Human β-defensin 3-combined gold nanoparticles for enhancement of osteogenic differentiation of human periodontal ligament cells in inflammatory microenvironments
... of human PDLCs (hPDLCs) through the coordination of AuNPs and hBD3 in inflammatory microenvironments; particularly, it is not clear that, when hBD3 combined AuNPs, whether their functions could be more than just a ...
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Legionella pneumophila induces human beta Defensin-3 in pulmonary cells
... The expression of hBD-3 in respiratory cells, especially in infections of the lung, is not well understood and was so far rather investigated in studies of oral infections as well as in epithelium of skin and intestine ...
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Original Article Expression of hBDs in gingival tissue in patients with cleft alveolus
... (human beta defensin) and clinical indexes in gingival tissue in patients with cleft alveolar who also suffering from periodontitis, 35 patients with cleft alveolar (age range from 12-19 years) and ...
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Differential expression, molecular cloning, and characterization of porcine beta defensin 114
... β- defensin 2 existed broad-spectrum antimicrobial activ- ities and immune modulating function ...[20]. Human beta defensin 114 exhibited strong antimicrobial activity against ...
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Original Article Dust mite vaccine enhances airway antibacterial host defense by up-regulating beta defensins in asthmatic mice
... [24]. Human beta defensin 2 (HBD-2) is the chief component of airway innate immunity, which is the first human defensins inducible expression by inflammation and ...mouse beta ...
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“HUMAN DEFENSIN PEPTIDES WITH ANTIMICROBIAL PROPERTIES: AN OVERVIEW” by Lalit Lata Jha, Darshika Shah, Rajesh KS, India.
... Human defensin peptides with antimicrobial properties are classified under antimicrobial peptides ...known human defensin peptides with antimicrobial functions have been identified and studied ...
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PPARγ as a sensor of lipase activity and a target for the lipase inhibitor orlistat
... of beta defensin-1, and ADRP by Orlistat (Figure 4) in Caco-2 cells along with the direct binding of Orlistat to PPARγ (Figure 2), is strong evi- dence that Orlistat is a PPARγ agonist since these genes are ...
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Toll-like receptor 5-mediated IL-17C expression in intestinal epithelial cells enhances epithelial host defense against F4+ ETEC infection
... T84 human colon IECs, the enterotoxin STb can induce redistribution and/or fragmentation of ZO-1, claudin-1, and occludin due to actin rearrange- ment [45, ...
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A Study of the Role of Gata6 in Definitive Endoderm Specification and Β-Cell Functionality by Genome Engineering of Pluripotent Stem Cells
... in vitro model system to study GATA6. Heterozygous mutations in this gene are the leading cause of pancreas agenesis while studies in mice do not replicate the human phenotype. Induced pluripotent stem cells were ...
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Fusobacterium nucleatum in Periodontal Health and Disease
... One of the most studied bacteria implicated in periodontal disease is F. nucleatum. It belongs to the Bacteroidaceae family and is a dominant micro-organism within the periodonticum. It is a gram-negative anaerobic ...
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Design and activity of a cyclic mini-β-defensin analog: a novel antimicrobial tool
... cells/200 µ L per well) into 96-well microtiter tissue culture plates for 24 hours in triplicate. The reduction in the prolifera- tion of the cells was evaluated by the 3-[4.5-dimethylthiazol-2 ...
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Intramolecular inhibition of human defensin HNP 1 by its propiece
... We used the baculovirus protein expression system to synthe- size proHNP-1, a transient precursor form of a human de- fensin. From this propeptide, CNBr cleavage generated ma- ture rHNP-1 that displayed the same ...
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Structural and functional characterisation of a novel bovine β defensin gene cluster
... B-actin Antimicrobial peptides Activator protein 1 Antigen presenting cell Spermadhesins aqnl Adenosine triphosphate transferase Bovine beta defensin Bovine endometrium cells sperm assoc[r] ...
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