Human Fatty Acid Binding Protein
The human fatty acid-binding protein family: Evolutionary divergences and functions
... C/EBP binding site, and it was found that this mutation exhibited sig- nificantly reduced competitive-binding capacity (50 per cent) for C/EBPa compared with the wild-type (WT) FABP4 ...
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Adipocytes promote cholangiocarcinoma metastasis through fatty acid binding protein 4
... free fatty acids (FAs), as well as to derive a wide variety of adipokines and signaling factors involved in tumor formation and progression ...several human cancers [22, ...
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Urinary excretion of liver-type fatty acid-binding protein reflects the severity of sepsis
... Fatty acid-binding proteins (FABPs) are members of the intracellular lipid-binding protein family and are expressed as 14–15 kDa proteins; they reversibly bind to hydrophobic ligands ...
10
Serum Intestinal Fatty Acid Binding Protein in Patients with Small Bowel Obstruction
... evidence for the resolution of those clinical issues. We have previously shown that bowel ischemia rap- idly caused the release of I-FABP from damaged entero- cytes in rodent experimental models. Serum I-FABP level rose ...
6
Exploring and Expanding the Fatty Acid Binding Protein superfamily in Fasciola species.
... The trematode liver flukes, Fasciola hepatica and F. gigantica, are the causative agents of fasciolosis, a foodborne zoonotic disease affecting grazing animals and humans worldwide. Liver fluke causes economic losses of ...
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Association of peroxisome proliferated activated receptor (ppar) and fatty acid binding protein (fabp2) gene polymorphisms on t2dm and insulin resistance on different populations
... The detection of DNA polymorphisms in human populations is an important approach to understand how functional genetic variants affect the predisposition of diseases (Evrim, 2012). A step to find out the likelihood ...
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REVIEW ARTICLE Usefulness of heart-type fatty acid binding protein in the emergency department
... heart-type fatty acid-binding protein relative to cardiac troponin T on admission in the early hours of acute coronary ...al. Human heart-type fatty acid-binding ...
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Reduced diversity and altered composition of the gut microbiome in individuals with myalgic encephalomyelitis/chronic fatigue syndrome
... Quantikine Human sCD14 Immunoassay (R&D Systems, Minneapolis, MN), and plasma LBP was measured by LBP soluble ELISA kit (Hycult Biotechnology, Uden, The Netherlands) according to the manufacturers’ ...
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Immunoglobulin E Reactivity of Recombinant Allergen Tyr p 13 from Tyrophagus putrescentiae Homologous to Fatty Acid Binding Protein
... IgE reactivity of the recombinant allergen. The reactivities of specific immu- noglobulin E (IgE) antibodies to the recombinant allergen were examined by ELISA. ELISA plates were coated with 100 l (0.1 M sodium ...
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The adipocyte fatty acid–binding protein aP2 is required in allergic airway inflammation
... adipocyte fatty acid–binding protein aP2 regulates systemic glucose and lipid ...by human airway epithelial cells and shows a striking upregulation following stimulation of epithelial ...
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Utility of urinary liver-type fatty acid-binding protein as a predictor of renal dysfunction in Japanese patients with HIV receiving tenofovir disoproxil fumarate with low urinary β2 microglobulin levels: a retrospective observational study
... with human immunodeficiency virus (HIV) ...Liver-type fatty acid–binding protein (L-FABP) is also a tubular marker, and expressed in the proximal tu- bules of the human kidney ...
5
Review: Omega-3 fatty acids transport through the placenta
... proteins, fatty acid transport proteins (FATPs, also known as SLC27A) are familiar for its cellular uptake of LC-PUFAs (Kazantzis and Stahl, ...both human and mouse placenta (Schaiff et ...at ...
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The changes in biomarkers for necrotising enterocolitis in premature calves with respiratory distress syndrome
... The fatty acid binding protein (FABP) family con- tains a number of cytoplasmic small size proteins with high organ ...sealing protein (Rahner et ...previous human infant ...
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An amino acid substitution in the human intestinal fatty acid binding protein is associated with increased fatty acid binding, increased fat oxidation, and insulin resistance
... intestinal fatty acid binding protein locus (FABP2) was investigated as a possible genetic factor in determining insulin action in the Pima Indian ...recombinant protein showed that the ...
8
Analysis of hepatic gene transcription in mice expressing insulin insensitive GSK3
... GSK3 (glycogen synthase kinase-3) regulation is proposed to play a key role in the hormonal control of many cellular processes. In- hibition of GSK3 in animal models of diabetes leads to normal- ization of blood glucose ...
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Schistosoma japonicum: The design and experimental evaluation of a multivalent DNA vaccine
... (fatty acid binding protein) and Sj23 (23 kDa membrane protein) have been recognized by WHO as protective antigens in hosts infected by ...
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Ulcerative colitis: functional analysis of the in-depth proteome
... Samples were homogenized with 250 µl cooled lysis buffer [8 M urea, 5% sodium deoxycholate (SDC), 100 mM triethylammonium bicarbonate buffer pH 8.5 (TEAB)] in MagNA Lyser Green Bead tubes (Roche Diag- nostics AG, ...
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Enzymes in lipid modification: From classical biocatalysis with commercial enzymes to advanced protein engineering tools
... etc.). Protein engineering allows to alter these properties and hence represents a key technology in modern biocatalysis (Bornscheuer and Kazlauskas, 2011; Bornscheuer et ...for protein engineering can be ...
5
Hepatoprotective role of liver fatty acid binding protein in acetaminophen induced toxicity
... Fatty acid binding protein (FABP) was first discovered in 1969 by Levi et ...Liver fatty acid binding protein (FABP1), named after the tissue in which it was first ...
7
The orphan nuclear receptor small heterodimer partner is required for thiazolidinedione effects in leptin-deficient mice
... and fatty liver ...promotes fatty acid oxidation and insulin sensitivity in muscle and liver, and the antidiabetic effects of a low dose of pioglit- azone were lost in mice in which adiponectin ...
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