Human glioma
Clathrin-mediated entry and cellular localization of chlorotoxin in human glioma
... normal human fibroblasts (A), NHA normal human astrocytes (B), and U373 human glioma (C) using the Colocalization Tool (as described in the ...in glioma cells (F) was compared to the ...
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Original Article Lipoma HMGIC fusion partner-like 3 (LHFPL3) promotes proliferation, migration and epithelial-mesenchymal transitions in human glioma cells
... malignant glioma is still ...malignant glioma tissues when compared with the normal brain tissues which is consistent with our analysis of LHFPL3 expression level of 20 pairs of human clini- cal ...
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Elevated expression of Dickkopf-1 increases the sensitivity of human glioma cell line SHG44 to BCNU
... in glioma and con- sidered as a serologic and prognostic ...12 human glioma cell lines, we found that the supernatant fluid and lysate of 9 cell lines had high level of DKK-1 protein and the other 3 ...
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In vitro antineoplastic effects of brivaracetam and lacosamide on human glioma cells
... Background: Epilepsy is a frequent symptom in patients with glioma. Although treatment with antiepileptic drugs is generally effective in controlling seizures, drug-resistant patients are not uncommon. Multidrug ...
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Original Article Tripartite motif-containing protein 37 is overexpressed in human glioma and its downregulation inhibits human glioma cell growth in vitro
... The human glioma cell line U87 was obtained from the Chinese Academy of Sciences (Bei- jing, China) and cultured in Dulbecco’s modi- fied Eagle’s medium (DMEM; Hyclone, Beijing, China) supplemented with 10% ...
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Morphological characterization of a human glioma cell l ine
... of human gliomas (Jacques et ...some human glioma cell lines (Roess- mann et ...a human adrenal tumor cell line, named SW-13, expressed vimentin filaments and clones derived from these cells ...
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Type I collagen gene suppresses tumor growth and invasion of malignant human glioma cells
... in human glioma cells ...to glioma, which is characterized by marked tumor cell proliferation and extensive local invasion, in order to examine the inhibitory effects of the overexpressed HCOL1A1 on ...
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Anti Fas/APO 1 antibody mediated apoptosis of cultured human glioma cells Induction and modulation of sensitivity by cytokines
... of human malignant glioma cells to IFN gamma and TNF ...antibody-induced glioma cell apoptosis whereas other cytokines including TNF beta, IL6, macrophage colony-stimulating factor, IL10 and IL13 had ...
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Roles of microRNA-99 family in human glioma
... Similar to other malignancies, we found in this study that the expression levels of miR-99a, miR-99b, and miR- 100 were all dramatically reduced in human glioma tissues compared to the normal controls. We ...
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The role of IFITM3 in the growth and migration of human glioma cells
... In recent few years the discovery of RNAi, a powerful tool to induce loss-of-function phenotypes through the posttranscriptional silencing of gene expression, has pro- vided new possibilities for cancer therapy [28-30]. ...
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Role of Rho GTPasas and PTEN in the migration of human glioma cells
... A role for Cdc42 in the aberrant migration of glioma cells was demonstrated here by expressing a dominant negative form of Cdc42 (N17Cdc42). As had previously been shown for primary rat embryonic fibroblasts, ...
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Visualization of spatiotemporal dynamics of human glioma stem cell invasion
... The human GSC line hG008 expressing ffLuc had a sphere-forming capacity (Fig. 1f ), but the cell prolifera- tion rate was not different from that of U87 cells. In the brains of mice implanted with 1 × 10 5 hG008 ...
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Role of Rho GTPases and PTEN in the migration of human glioma cells
... Tumor suppressor PTEN inhibits integrin- and growth factor-mediated mitogen-activated protein (MAP) kinase signaling pathways, J Cell Biol 143,1375-83. Proliferation[r] ...
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Correlation of microrna-372 upregulation with poor prognosis in human glioma
... in glioma tissues compared with paired adjacent non- neoplastic brain ...of glioma patients, indicating that this miRNA may be involved in the development of human ...
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Original Article Silencing of TIPE3 suppresses proliferation of human glioma cells via AKT signaling pathway
... To illustrate the molecular mechanism by which TIPE3 regulates the proliferation of glioma cells, western blots were performed to detect the related protein expression. As depicted in Figure 4, Silencing of TIPE3 ...
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Influences of surface coatings and components of FePt nanoparticles on the suppression of glioma cell proliferation
... malignant glioma therapy was evaluated in vitro using three typical brain glioma cell lines (human glioma U251 cells, human astrocytoma U87 cells, and human neuroglioma H4 cells) ...
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Original Article Ectopic expression of AP-2α transcription factor suppresses glioma progression
... in human glioma, and appeared to be the most frequent molecu- lar change in astrocytic tumor progression from lower to higher grade, although no significant effect of AP-2α on survival was observed ...in ...
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Original Article Comparisons between bio-radiation effects of X-rays and carbon-ion irradiation on glioma stem cells
... used human glioma cancer stem cells and glioma virus-induced mice model irradiated by carbon ions or X-rays to investigate whether heavy ions offering a radio-biological advantage, by effectively ...
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Original Article Function and mechanism of long non-coding RNA KIAA0495 in glioma
... BALB/c-nu/nu nude mice were purchased from Shanghai silaike experiment Co., Ltd, which was 4-6 weeks old, of either sex, 18-21 g, and under the condition of SPF level feeding. Human glioma U251 cells ...
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In vitro enhancement of dendritic cell mediated anti glioma immune response by graphene oxide
... Malignant glioma has extremely poor prognosis despite combination treatments with surgery, radiation, and ...of glioma, but its efficacy generally needs further ...T98G human glioma cell line ...
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