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human gut microbiome

Plasticity in the Human Gut Microbiome Defies Evolutionary Constraints

Plasticity in the Human Gut Microbiome Defies Evolutionary Constraints

... and human populations practicing traditional subsistence, relative to primates that rely on diets with the highest content of complex fibers ...the human gut microbiome (39, 40), not all fibers ...

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Competitive lottery-based assembly of selected clades in the human gut microbiome

Competitive lottery-based assembly of selected clades in the human gut microbiome

... Our analysis has focused on testing a simple assembly schema and on identifying groups that are likely governed by the lottery schema. Importantly, however, there are likely many other processes that are at play in the ...

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Fire in the Forest: Adverse Effects of Antibiotics on the Healthy Human Gut Microbiome

Fire in the Forest: Adverse Effects of Antibiotics on the Healthy Human Gut Microbiome

... multidrug-resistant human pathogens, remains a serious public health crisis across the ...The human gut microbiome regulates essential human functions including digestion, energy ...

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Proteobacteria explain significant functional variability in the human gut microbiome

Proteobacteria explain significant functional variability in the human gut microbiome

... healthy human gut microbiota, we uncovered thousands of variable gene families whose abundances were more variable than ...the human gut microbiome, we found that these phyla were ...

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Impact of Dietary Resistant Starch on the Human Gut Microbiome, Metaproteome, and Metabolome

Impact of Dietary Resistant Starch on the Human Gut Microbiome, Metaproteome, and Metabolome

... and met other eligibility criteria. Male participants ( ⬎ 20 years) and postmenopausal women ( ⱖ 43 years, no menses for ⱖ 3 years or no menses for ⱖ 1 year and ⬍ 3 years and additionally a follicle-stimulating hormone ...

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Crystal structure and activity studies of the C11 cysteine peptidase from parabacteroides merdae in the human gut microbiome

Crystal structure and activity studies of the C11 cysteine peptidase from parabacteroides merdae in the human gut microbiome

... Clan CD cysteine peptidases, a structurally related group of peptidases that include mammalian caspases, exhibit a wide range of important functions, along with a variety of specificities and activation mechanisms. ...

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Selecting age-related functional characteristics in the human gut microbiome

Selecting age-related functional characteristics in the human gut microbiome

... Age has been studied as a potential characteristic influ- encing the constitution and activity of gut microbiomes. Here we aim to identify various functional signatures that differentiate metagenomes over a broad ...

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Alterations of the human gut microbiome in multiple sclerosis

Alterations of the human gut microbiome in multiple sclerosis

... the gut microbiota in MS provides initial insights into understanding the potential role for the microbiome in this disease, our study has certain ...the gut microbiome and the MS ...in ...

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Abstract: The human gut microbiome includes beneficial, commensal and pathogenic bacteria that

Abstract: The human gut microbiome includes beneficial, commensal and pathogenic bacteria that

... (ExPEC) including ST131 may occupy other environments like the urinary tract or bloodstream where they express genes enabling AMR and host adhesion like type 1 fimbriae. The extent to which non-pathogenic gut E. ...

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The influence of a short-term gluten-free diet on the human gut microbiome

The influence of a short-term gluten-free diet on the human gut microbiome

... fecal human-β-defensin-2 as a marker for defense against invading microbes [28, 29]; fecal chromogranin A as a marker for neuro-endocrine system activation [30–32]; fecal short-chain fatty acids (SCFA) secretion ...

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Compositional and Functional Differences in the Human Gut Microbiome Correlate with Clinical Outcome following Infection with Wild Type Salmonella enterica Serovar Typhi

Compositional and Functional Differences in the Human Gut Microbiome Correlate with Clinical Outcome following Infection with Wild Type Salmonella enterica Serovar Typhi

... RNA-seq taxonomic identification and differential expression analysis. Raw sequence data were processed with adaptive quality trimming and adapter removal using in-house quality control (QC) pipelines. rRNA was filtered ...

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Microbial Eukaryotes: a Missing Link in Gut Microbiome Studies

Microbial Eukaryotes: a Missing Link in Gut Microbiome Studies

... the human gut microbiome, emergent studies have provided exciting new findings that involve microbial ...the gut microbiome, likely capable of influencing the overall microbiome ...

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Functional profiling of the gut microbiome in disease-associated inflammation

Functional profiling of the gut microbiome in disease-associated inflammation

... the human gut microbiome during initiation and progression of complex ...the microbiome and their distinct patterns in early versus late ...of gut microbial communities remain more ...

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The gut microbiome in cardio-metabolic health

The gut microbiome in cardio-metabolic health

... the gut microbiota rather than marker genes alone, a less biased and higher-resolution view of the bacterial composition can be acquired through comparison with bacterial reference genomes and microbial gene ...

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Strain-level dissection of the contribution of the gut microbiome to human metabolic disease

Strain-level dissection of the contribution of the gut microbiome to human metabolic disease

... Integrating metagenomic and metabolomic approaches In a proof-of-principle study, we collected urine and fecal samples from a four-generation, seven-member Chinese family over monthly intervals [61]. This time- series ...

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Differences in the faecal microbiome in Schistosoma haematobium infected children vs  uninfected children

Differences in the faecal microbiome in Schistosoma haematobium infected children vs uninfected children

... The gut microbiome can be affected by antibiotic ...the gut microbiome has not yet been ...the gut microbiome remains stable after a single antihelminthic treatment in both ...

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Gut microbiome of native Arab Kuwaitis

Gut microbiome of native Arab Kuwaitis

... the gut microbiome of people in the Arabian Peninsula has focused on individ- uals from Saudi Arabia [23, 24], and describes the domi- nant phyla to be Firmicutes and ...the gut microbiome ...

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Allometry and Ecology of the Bilaterian Gut Microbiome

Allometry and Ecology of the Bilaterian Gut Microbiome

... Community structure, phylogeny, and lifestyle. We next compared bilaterian gut community structures on a phylogenetic scaffold using UniFrac. In this method, two samples are compared by arranging their OTU ...

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Gut microbiome and CAR-T therapy

Gut microbiome and CAR-T therapy

... The microbiome studies have not expanded to CAR T-cell or other types of novel immune-engaging therapy yet and the earliest evidence of the role of antibiotics in ACT setting has been ...baseline gut taxa ...

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Gut microbiome, obesity, and metabolic dysfunction

Gut microbiome, obesity, and metabolic dysfunction

... The prevalence of obesity and related disorders such as metabolic syndrome has vastly increased throughout the world. Recent insights have generated an entirely new perspective suggesting that our microbiota might be ...

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