Human THP-1 macrophages
Sulforaphane rescues amyloid-β peptide-mediated decrease in MerTK expression through its anti-inflammatory effect in human THP-1 macrophages
... in human THP-1 macrophages challenged with A β ...β 1-42 elicited a marked decrease in MerTK expression along with increased intracellular Ca 2+ level and induction of proinflammatory ...
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III. Ion Channel Expression in PMA-differentiated Human THP-1 Macrophages
... nondividing macrophages they become capable of a large variety of responses, including chemotaxis, phagocytosis, and se- cretion of numerous cytokines and other ...the human leuke- mia cell line, ...
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Resveratrol distinctively modulates the inflammatory profiles of immune and endothelial cells
... impaired by RES, suggesting that it dampened the classical activation of macrophages. With regard to CKs, RES blunted CCL4/MIP-1β and CCL5/RANTES and therefore the recruitment of monocyte and activated T ...
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Rhinovirus Replication in Human Macrophages Induces NF-κB-Dependent Tumor Necrosis Factor Alpha Production
... nondifferentiated THP-1 cells (29). The pattern of infec- tion in THP-1-derived M is similar with that found in respi- ratory epithelial cells, where only a small percentage of the cells ...
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Macrophage phenotype in response to ECM bioscaffolds
... of macrophages has typically been limited to small number of non- specific cell surface markers or expressed ...derived macrophages (BMDM) and a transformed human mononuclear cell line ...
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Role of interleukin 1 beta in foam cell formation of THP 1 macrophages
... Human THP-1 monocytic leukemia cells were obtained from the cell band of the Institute of Biochemistry and Cell Biology, Shanghai Institute for Biological ...
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Curcumin induces the apoptosis of human monocytic leukemia THP 1 cells via the activation of JNK/ERK Pathways
... immature THP-1 mono- cytic cells to mature THP-1 ...treated THP-1 ...ted THP-1 cells (Figure ...induces human monocytic leukemic THP-1 cell ...
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Mono-ethylhexyl phthalate stimulates prostaglandin secretion in human placental macrophages and THP-1 cells
... the THP-1 cell line as a model to compare to primary placental macrophages because these cells are easily obtained, are genetically clonal, and represent a potential alternative model to primary ...
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Human immunodeficiency virus type 1 envelope protein does not stimulate either prostaglandin formation or the expression of prostaglandin H synthase in THP-1 human monocytes/macrophages.
... CD4 1 monocytes with the envelope protein of HIV, gp120, stimulated the formation of prostaglandins and the release of monokines ...and macrophages (4, ...
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Sap6, a secreted aspartyl proteinase, participates in maintenance the cell surface integrity of Candida albicans
... Because macrophages may be the first encountered host defense cells during the invasive process of pathogens, we applied co-culture of ...and THP-1 human monocytes to evaluate the pathogenic ...
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Effect of n-3 fatty acids on the expression of inflammatory genes in THP-1 macrophages
... Inflammation is a condition which contributes to a range of human diseases [7, 27]. EPA and DHA are the major n-3 FAs found in oily fish and fish oil supplements. There is substantial evidence that these FAs are ...
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I. Ion Channels in Human THP-1 Monocytes
... in human monocyte-derived macro- phages (Nelson, Jow & Jow, ...In human neutro- phils, an outwardly-rectifying Cl − conductance is acti- vated by cell swelling (Stoddard, Steinbach & Simcho- witz, ...
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Effect of different concentrations of omega-3 fatty acids on stimulated THP-1 macrophages
... levels. Human studies investigating the impact of n-3 FA intake against non-CVD were unfor- tunately not consistent with the data collected in pre- clinical ...
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Mebendazole induced M1 polarisation of THP 1 macrophages may involve DYRK1B inhibition
... Previous studies have demonstrated that IL1β release require two signals. The first is provided by toll-like- receptor-mediated NF-kappaB activation whereas the second can be mediated by danger signals such as ...
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Gene expression profiling of macrophages: implications for an immunosuppressive effect of dissolucytotic gold ions
... the human THP-1 cell line which shares many properties with human monocyte-derived macrophages [32] but does not resemble monocytes-macrophages isolated from human ...that ...
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Enhanced uptake of multiple sclerosis-derived myelin by THP-1 macrophages and primary human microglia
... for THP-1 macrophages after 24 hours of incubation with ...by THP-1 macrophages after 24 hours of incubation with ...by THP-1 macrophages after 6 hours of ...
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High glucose induces a priming effect in macrophages and exacerbates the production of pro-inflammatory cytokines after a challenge
... from THP-1 macrophages under high glucose ...from THP-1 macrophages exposed to normal glucose conditions ...in human primary macrophages exposed to high glucose ...
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Monocyte-derived factors including PLA2G7 induced by macrophage-nasopharyngeal carcinoma cell interaction promote tumor cell invasiveness
... Tumor-associated macrophages (TAMs) foster tumor progression through production of soluble mediators that support proliferation, angiogenesis, survival and invasion of malignant ...of macrophages in the ...
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Release of human immunodeficiency virus by THP-1 cells and human macrophages is regulated by cellular adherence and activation.
... Ten days after infection with HIV-1RF, THP-1 cells were washed three times in PBS to remove all cell-free virus, resuspended in fresh medium, and cultured in nonadherent conditions in ti[r] ...
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Effect of cyclooxygenase inhibition on cholesterol efflux proteins and atheromatous foam cell transformation in THP 1 human macrophages: a possible mechanism for increased cardiovascular risk
... of disturbance in the balance of thromboxanes and prostaglan- dins on platelet aggregability alone are insufficient to explain the heightened cardiovascular risk. Furthermore, the expres- sion of COX-2 on platelets and ...
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