Hydroxyethyl Starch
Effect of restrictive fluid therapy with hydroxyethyl starch during esophagectomy on postoperative outcomes: a retrospective cohort study
... Colloids are very effective intravascular volume ex- panders. Compared with crystalloids, relatively small amounts of a colloid solution can increase plasma volume more during the resuscitation period. However, there are ...
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Systematic review of randomized clinical trials on the use of hydroxyethyl starch for fluid management in sepsis
... respectively. Hydroxyethyl starch increased the incidence of acute renal failure compared both with gelatin (odds ratio, ...among hydroxyethyl starch recipients (odds ratio, ...-1 ...
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Fluid loading in abdominal surgery saline versus hydroxyethyl starch (FLASH Trial): study protocol for a randomized controlled trial
... Two large-scale pragmatic multicenter trials have re- cently been performed to compare crystalloids and different new-generation and low-molecular-weight preparations of hydroxyethyl starch (HES) in ...
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Conjugation of Hydroxyethyl Starch to Desferrioxamine (DFO) Modulates the Dual Role of DFO in Yersinia enterocolitica Infection
... The iron chelator desferrioxamine (DFO) B is widely used in the therapy of patients with iron overload. As a side effect, DFO may favor the occurrence of fulminant Yersinia infections. Previous work from our laboratory ...
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Perioperative clinical and economic outcomes associated with replacing first-generation high molecular weight hydroxyethyl starch (Hextend®) with low molecular weight hydroxyethyl starch (Voluven®) at a large medical center
... One of these semisynthetic products, Voluven®, was recently introduced into the US market. It has a lower molecular weight (150 kD) and molar substitution (0.4) and therefore has a theoretical lower plasma accumula- tion ...
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Effects of hydroxyethyl starch 130/0.4 on the kidney tissue of rats with ureteral obstruction
... Conclusion: If indicated, HES should be used with caution in cases of UUO, but not in the cases of bilateral ureteral obstruction. Other aspects of these findings, including the clinical significance and practical ...
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Comparison of hydroxyethyl starch regulatory summaries from the Food and Drug Administration and the European Medicines Agency
... This article aims to highlight the positions of the Food and Drug Administration and the European Medicines Agency regarding use and marketing of hydroxyethyl starch (HES) products, and how these have ...
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Efficiency of 7 2% hypertonic saline hydroxyethyl starch 200/0 5 versus mannitol 15% in the treatment of increased intracranial pressure in neurosurgical patients – a randomized clinical trial [ISRCTN62699180]
... Abstract Introduction This prospective randomized clinical study investigated the efficacy and safety of 7.2% hypertonic saline hydroxyethyl starch 200/0.5 7.2% NaCl/HES 200/0.5 in compa[r] ...
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Hydroxyethyl Starch- Friend or Foe?
... Hydroxyethyl starch (HES) products are commonly employed for volume resuscitation in the perioperative period as well as in ICU patients being treated for sepsis and other ...
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Interactions between the volume effects of hydroxyethyl starch 130/0 4 and Ringer´s acetate
... 21. Perner A, Haase N, Guttormsen AB, Tenhunen J, Klemenzson G, Åneman A, Madsen KR, Møller MH, Elkjær JM, Poulsen LM, Bendtsen A, Winding R, Steensen M, Berezowicz P, Søe-Jensen P, Bestle M, Strand K, Wiis J, White JO, ...
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Hydroxyethyl starch versus Ringer solution in cardiopulmonary bypass prime solutions (a randomized controlled trial)
... of hydroxyethyl starch can destroy the renal functions, but this assertion was investigated only in a small number of studies and the results are ...
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Effect of fluid loading with normal saline and 6% hydroxyethyl starch on stroke volume variability and left ventricular volume
... The patients were randomly assigned to receive a 500 mL infusion of hydroxyethyl starch (HES; HES group) or saline (Saline group). Randomization was performed using a random number table. Standardized ...
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In Vitro impairment of whole blood coagulation and platelet function by hypertonic saline hydroxyethyl starch
... saline hydroxyethyl starch has been introduced for rapid restoration of normovolemia following severe ...as hydroxyethyl starch, impair coagulation and platelet function; the former by ...
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Effects of synthetic colloids on oxidative stress and inflammatory response in hemorrhagic shock: comparison of hydroxyethyl starch 130/0 4, hydroxyethyl starch 200/0 5, and succinylated gelatin
... of hydroxyethyl starch 130/0.4, hydroxyethyl starch ...(hydroxyethyl starch 130/0.4, hydroxyethyl starch ...
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Adverse effects of hydroxyethyl starch (HES 130/0 4) on intestinal barrier integrity and metabolic function are abrogated by supplementation with Albumin
... (Alb), hydroxyethyl starch (HES) a synthetic nonionic starch derivate available in different molecular weight and substitution forms, is one of the most effective and commonly used colloids in Can- ...
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Original Article The influence of hypertonic sodium chloride hydroxyethyl starch 40 on patient recovery after gastrointestinal carcinoma radical resection
... chloride hydroxyethyl starch 40 (HSH 40) is increasingly recognized as an important liquid in clinical practices recently, because it can suppress plasma inflammatory cytokines re- lease, maintaining ...
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Comparing the effect of hydroxyethyl starch 130/0 4 with balanced crystalloid solution on mortality and kidney failure in patients with severe sepsis (6S Scandinavian Starch for Severe Sepsis/Septic Shock trial): Study protocol, design and rationale for a double blinded, randomised clinical trial
... weight hydroxyethyl starch (HES) may cause acute kid- ney failure (AKF) in patients with severe sepsis as observed in a recent meta-analysis ...- hydroxyethyl groups per glucose), but found divergent ...
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Large volume infusions of hydroxyethyl starch during cardiothoracic surgery may be associated with postoperative kidney injury: propensity-matched analysis
... Maintaining intravascular volume by fluid administra- tion is essential to maintain stable hemodynamic status, but optimal perioperative fluid management including the types and the amount of fluid infused is a matter of ...
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Hydroxyethyl starch 6%, 130/0.4 vs. a balanced crystalloid solution in cardiopulmonary bypass priming: a randomized, prospective study
... 6% hydroxyethyl starch ...in hydroxyethyl starch group (p < 0.05 for each). Hydroxyethyl starch did not increase postoperative blood loss, amount of blood and fresh frozen ...
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Coagulation during elective neurosurgery with hydroxyethyl starch fluid therapy: an observational study with thromboelastometry, fibrinogen and factor XIII
... Hydroxyethyl starch (HES) is a colloid solution that can be used to replace initial blood loss and to treat hypovolemia during elective surgery. However, HES can induce a hypocoagulable state by diluting ...
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