hypoxic-ischemic injury
TRPM7 inhibitor carvacrol protects brain from neonatal hypoxic-ischemic injury
... to hypoxic- ischemic ...brain injury in an adult mouse MCAO model ...Neonatal hypoxic-ischemic brain injury leads to motor and cogni- tive deficits, and seizures ...
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Multipotent adult progenitor cells for hypoxic-ischemic injury in the preterm brain
... of hypoxic-ischemic injury in the preterm brain [14, ...CNS injury [9, ...the ischemic brain ...brain injury after stroke ...brain injury after global HI, temporal ...
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Inhibition of miRNA-210 reverses nicotine-induced brain hypoxic-ischemic injury in neonatal rats
... brain injury in the developing ...in ischemic disease is ...to ischemic injury to the brain [39] and up-regulation of miR-210 protects cells from hypoxia-induced apoptosis ...the ...
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Neuroinflammation and MMPs: potential therapeutic targets in neonatal hypoxic-ischemic injury
... to hypoxic-ischemic insults during the neonatal or perinatal developmental periods produces various forms of ...of hypoxic-ischemic injury, there is a growing need for effective ...
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Anatomic Localization of Dyskinesia in Children with “Profound” Perinatal Hypoxic Ischemic Injury
... that injury to the STN is a common finding in dyskinetic CP (15/20) and less common in spastic CP ...PCWM injury; damaged descending corticospinal tracts mask the aberrant neuronal output from the injured ...
6
Chaperones, protein aggregation, and brain protection from hypoxic/ischemic injury
... Unfolded or misfolded proteins have exposed hydrophobic segments that render them prone to aggregation. Protein aggregates are thought to be toxic to the cell (Taylor et al., 2002), so to avoid aggregation, abnormal ...
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MR Imaging Quantification of Cerebellar Growth Following Hypoxic Ischemic Injury to the Neonatal Brain
... This study was approved by the hospital ethics committee. Parental consent was obtained for each scan. Term-born in- fants (greater than 37 weeks’ gestation) presenting with an encephalopathy and/or seizures presumed due ...
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Ceftriaxone attenuates hypoxic-ischemic brain injury in neonatal rats
... In our studies, GLT1 protein expression in the whole brain lysate of P7 rat did not change after ceftriaxone treatment. But, immunohistochemical study showed that pre-treatment with ceftriaxone induced GLT1 protein ...
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Brain Injury Patterns in Hypoglycemia in Neonatal Encephalopathy
... brain injury in HIE or hypoglycemia, but this large cohort study provides novel information on imaging patterns seen when these 2 condi- tions ...pulvinar injury are most predictive of clinical hypoglycemia ...
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The predictive accuracy of hypoxic scoring for prediction of adverse outcome in neonates born with asphyxia
... Hypoxic ischemic injury is one of the causes of depressed Apgar ...of hypoxic-ischaemic injury following a known perinatal insult such as placental abruption or cord accident or if ...
5
Free Radical Injury and Blood-Brain Barrier Permeability in Hypoxic-Ischemic Encephalopathy
... the ischemic neonatal brain is cytotoxic, contributing to neurodegen- eration after hypoxic-ischemic injury because of its re- action with the superoxide radical with the formation of the ...
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Mitochondrial Optic Atrophy (OPA) 1 Processing Is Altered in Response to Neonatal Hypoxic-Ischemic Brain Injury
... of hypoxic-ischemic injury (HI) there is an initial depletion of ATP, phosphocreatine and glucose within the brain followed by a transient recovery to almost physiological levels ...brain ...
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Resveratrol post-treatment protects against neonatal brain injury after hypoxia-ischemia
... Neonatal hypoxic-ischemic brain injury is a devastating disease with limited treatment ...neonatal hypoxic-ischemic injury is not ...neonatal hypoxic- ischemic ...
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Measurement of Lactate Content and Amide Proton Transfer Values in the Basal Ganglia of a Neonatal Piglet Hypoxic Ischemic Brain Injury Model Using MRI
... after hypoxic-ischemic brain injury, and investigate the non- invasive detection of intracellular pH in brain tissues are few but ...in hypoxic-ischemic ...
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The Interaction of Stroke Risk Factors, Clinical Outcomes and Matrix Metalloproteinase 9 Levels with the Reduction of Vascular Endothelial Growth Factor A Levels at the Incidence of Brain Edema in Acute Ischemic Stroke Patients
... Via an interaction with the VEGF receptor, VEGF may induce vasodilatation and vascular hypotension. In contrast, the disruption of VEGF signaling may cause hypertension. Indeed, the increasing incidence of hypertension ...
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The potential of erythropoietin to treat asphyxia in newborns
... this study consisted of 3 hours at 32.5 ° C–33 ° C immediately after the hypoxic period was complete. Epo was dosed at 5,000 U/kg given intraperitoneally immediately after hypo- thermia and repeated 24 and 48 ...
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Original Article Neuroprotective and regenerative effects of melatonin on hypoxic-ischemic brain injury in neonatal rats
... With the advancement of nerve regeneration research, in 1992, Richards et al. and Reynolds et al. isolated neural stem cells from the stria- tum and hippocampus of adult rats for the fi- rst time [11, 12]. Their studies ...
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Clinical pathophysiology of hypoxic ischemic brain injury after cardiac arrest: a “two hit” model
... Clarifying the underlying pathophysiology of HIBI is imperative and has been the focus of considerable research to identify therapeutic targets. Most notably, targeted temperature management has been studied rigorously ...
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Use of estetrol with other steroids for attenuation of neonatal hypoxic-ischemic brain injury: to combine or not to combine?
... Estetrol (E4), estradiol (E2) and progesterone (P4) have important antioxidative and neuroprotective effects in neuronal system. We aimed to study the consequence of combined steroid therapy in neonatal ...
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REVIEW ARTICLE Intrapartum Hypoxic-Ischemic Cerebral Injury and Subsequent Cerebral Palsy: Medicolegal Issues
... distinctive and often discussed immediate sequelae in newborns is intrapartum asphyxia. The magni- tude of the changes in the blood gas measurements obtained from the cord umbilical artery that war- rants the term birth ...
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