I-FABP
Is I-FABP not only a marker for the detection abdominal injury but also of hemorrhagic shock in severely injured trauma patients?
... with I-FABP in the present ...with I-FABP levels on admission. Overall, our results suggest that I-FABP could serve as a novel marker for the detection of hemorrhagic ...
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The role of I-FABP as a biomarker of intestinal barrier dysfunction driven by gut microbiota changes in obesity
... of I-FABP in the mature epithelium of villi facilitates its leakage into the circulation from enterocytes when intestinal mucosal damage occurs ...that I-FABP is re- leased into the ...
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Calprotectin and Intestinal Fatty Acid Binding Protein (I-FABP) Level in Preterm Neonates with Necrotizing Enterocolitis
... standard were incubated in I-FABP-specific antibody. Antibody will bind to I-FABP, then conjugate with streptavidin-peroxidase. This conjugation will further be reacted with substrate. ...
10
Carbohydrate and protein intake during exertional heat stress ameliorates intestinal epithelial injury and small intestine permeability
... al. 2001). Although small intestine permeability was not reduced and there was no further benefit obtained from the addition of glutamine at a similar rate to the WPH (Lambert et al. 2001). Whereas, in the current study, ...
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Increased adhesion of Plasmodium falciparum infected erythrocytes to ICAM 1 in children with acute intestinal injury
... disease. Adults with acute malaria have reduced absorptive capacity as well as increased intestinal permeability meas- ured using a differential sugar absorption test, the highest ratios being noted in severe disease ...
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Endotoxaemia is common in children with Plasmodium falciparummalaria
... We suggest the following hypothesis: A proportion of children suffering from malaria experience loss of the barrier function of the gut due to parasite sequestration (and reduced microcirculatory flow), inflammation or ...
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Urinary excretion of liver-type fatty acid-binding protein reflects the severity of sepsis
... unit; I-FABP/ FABP2: Intestinal-type fatty acid-binding protein; Il-FABP/FABP6: Ileal-type fatty acid binding protein; L-FABP/FABP1: Liver-type fatty acid-binding protein; LOOH: Lipid ...
10
Effects of continuous renal replacement therapy on intestinal mucosal barrier function during extracorporeal membrane oxygenation in a porcine model
... dysfunction. I-FABP is low-molecular-weight protein specifically located in epithelial cells of small bowel mucosa which is rapidly released into the circula- tion after injury of intestinal mucosal barrier ...
9
Current status of laboratory and imaging diagnosis of neonatal necrotizing enterocolitis
... of I-FABP might serve as a diagnostic marker for early in- testinal mucosal compromise, such as NEC ...of I-FABP to be a specific marker for early identification of severe NEC (Bell’s stage ...
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Reduced diversity and altered composition of the gut microbiome in individuals with myalgic encephalomyelitis/chronic fatigue syndrome
... in plasma samples by commercially available enzyme- linked immunosorbent assays (ELISA). Plasma sCD14 was quantified using the Quantikine Human sCD14 Immunoassay (R&D Systems, Minneapolis, MN), and plasma LBP was ...
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Rapid development of intestinal cell damage following severe trauma: a prospective observational cohort study
... plasma i-FABP levels of all trauma patients on admit- tance and at days 1 and 2 were compared with healthy control ...between i-FABP values and the pres- ence of shock and extent of injury ...
7
PubMedCentral-PMC5744930.pdf
... On the other hand, intestinal fatty-acid binding protein (I-FABP) is expressed in epithelial cells of the mucosal layer of the small intestine tissue [42]. When intestinal mucosal damage occurs due to ...
11
Original Article N-terminal pro-B-type natriuretic peptide as a marker of blunt cardiac contusion in trauma
... Some studies introduced serum h-FABP as a marker for early evaluation of myocardial dam- age [8, 25]. Due to the advantage of this pro- tein’s features such as being low-molecular weight and cytosolic ...
7
Increased leptin and A-FABP levels in relapsing and progressive forms of MS
... To the best of our knowledge this is the first study to ex- plore the role of leptin and A-FABP in progressive and relapsing subcategories of untreated adult- and pediatric- onset MS patients. We found the highest ...
8
Effect of DanQi Pill on PPARα, lipid disorders and arachidonic acid pathway in rat model of coronary heart disease
... According to lipid infiltration theory of CHD, abnor- mal deposition of lipid in subendothelial layer of artery causes narrowing of coronary arteries, which will even- tually lead to CHD [6]. Studies have shown that high ...
10
Adipose tissue FABP deficiency promotes metabolic reprogramming and positively impacts healthspan
... exchange ratios determined from metabolic cage experiments to determine utilization. These data however, are only a fractional representation of metabolite flux and extrapolations towards substrate utilization from these ...
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Phyletic distribution of fatty acid-binding protein genes
... and FABP genes were directly retrieved from the ...Candidate FABP genes were identified using TBlastN, with experimentally or putatively identified FABP gene(s) from a closely related species as a ...
9
Clinical significance of urinary L-FABP in the emergency department
... The diagnosis and severity of acute kidney injury (AKI) are defined based on the Risk, Injury, Failure, Loss, End- stage kidney disease; Acute Kidney Injury Network; and Kidney Disease: Improving Global Outcomes (KDIGO) ...
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Adipocyte/macrophage fatty acid–binding proteins contribute to metabolic deterioration through actions in both macrophages and adipocytes in mice
... Hence, FABP deficiency created in either macrophages or adipo- cytes did not have a major impact on the number of macrophages present in adipose tissue under the experimental conditions used in this ...the ...
12
Identification of a C-FABP-PPARγ-VEGF axis promoting tumorigenicity in prostate cancer cells
... 22RV1, PC3-M, PC3-M-PPARγ-si-H and PC3-M-3 prostate cancer cell lines were cultured in normal cell culture condition up to 60-80% confluency before harvesting and seeding into 24-well plates. 5×10 4 cells/well in 1ml ...
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