IFN-γ, interferon-γ
Protective effect of the methanol extract from Cryptotaenia japonica Hassk against lipopolysaccharide induced inflammation in vitro and in vivo
... pattern; IFN- γ : Interferon- γ ; NK cells: Natural killer cells; LPS: Lipopolysaccharide; NO: Nitric oxide; iNOS: Inducible nitric oxide synthase; TNF- α : Tumor necrosis factor- α ; IL-6: ...
7
MAPKAPK2: the master regulator of RNA-binding proteins modulates transcript stability and tumor progression
... cells; IFN γ : Interferon- γ ; IGF: Insulin-like growth factor; IL: Interleukin; LPS: Lipopolysaccharide; MAP2K: MAPK kinase; MAP3K: MAPK kinase kinase; MAPKAPK2 or MK2: Mitogen-activate[r] ...
18
The human microglial HMC3 cell line: where do we stand? A systematic literature review
... 1; IFN γ : Interferon- γ ; II: Interferon- γ /interleukin-1 β ; IL: Interleukin; iNOS: Inducible nitric oxide synthase; IP-10: Interferon- γ inducible protein 10; ...
24
Construction and evaluation of a novel humanized HER2 specific chimeric receptor
... A cytokine release assay was performed by coculture of 10 5 T cells with 10 5 target cells per well in triplicate in 96-well flat-bottom plates in a 200-μl volume of complete medium. In addition, wells containing T cells ...
10
Interferon-γ enhances the antifibrotic effects of pirfenidone by attenuating IPF lung fibroblast activation and differentiation
... myofibroblasts, IFN-γ treatment results in the inhibition of COL1A1 gene expression and total collagen secretion ...combined IFN- γ and PFD sig- nificantly inhibited fibroblast differentiation ...
14
Successful control of juvenile dermatomyositis-associated macrophage activation syndrome and interstitial pneumonia: distinct kinetics of interleukin-6 and -18 levels
... We studied serum cytokine profiles in this patient during the acute (days 4, 6), subacute (day 12) or convalescent phase (day 50) of JDM-MAS with IP. Multi-target streaming protein quantitative technology (BD-Pharmingen ...
5
Interferon-γ promotes gastric lymphoid follicle formation but not gastritis in Helicobacter-infected BALB/c mice
... identified IFN-γ to be an important mediator in the B and T cell interactions required for gastric MALT lymphoma formation [37, 40, ...Furthermore, IFN-γ was shown to be highly expressed in ...
9
Accuracy of the interferon γ release assay for the diagnosis of active tuberculosis among HIV seropositive individuals: a systematic review and meta analysis
... In the past 15 years, as an immunodiagnostic method, the interferon-γ (IFN-γ) release assay (IGRA) was devel- oped to distinguish patients suffering from TB. The IGRA is a blood test that ...
11
Original Article Auxiliary diagnostic value of γδΤ cell, IL-17, and IFN-γ levels in peripheral blood and bronchoalveolar lavage fluid for lung cancer complicated with chronic obstructive pulmonary disease
... and interferon-γ (IFN-γ) levels in peripheral blood (PB) and bronchoalveolar lavage fluid (BALF) for lung cancer complicated with chronic obstructive pulmonary disease ...and ...
9
Inducible NO synthase: role in cellular signalling
... and interferon-γ (IFN-γ) are strong inducers of iNOS in monocytes, whereas the cytokines TNF- α and IL-1β have, if any, only marginal ...LPS, IFN-γ, IL-1β and TNF-α enhance iNOS ...
9
Disseminated Mycobacterium avium complex infection mimicking malignancy in a patient with anti IFN γ autoantibodies: a case report
... infection. IFN-γ is synthesised by T cells and NK cells under IL-12/23 ...turn, IFN-γ can activate macrophages, which destroy intracellular ...microbes. IFN-γ/IL-12/23 axis plays ...
5
Local cytokines and clinical symptoms in children with allergic rhinitis after different treatments
... of interferon-γ (IFN-γ) and interleukin-5 (IL-5) in nasal lavage fluid from children with allergic rhinitis after different types of pharmacologic treatment (mometasone, montelukast, or ...
6
Association of genetic polymorphisms in interferon-γ, interleukin-6 and transforming growth factor-β1 gene with oral lichen planus susceptibility
... various healthy ethnic populations clearly indicated eth- nic variations (Table 4). The frequency of AA genotype varies from 1.60 % in German to 83.51 % in Japanese while frequency of AT genotype from 16.49 % in Japanese ...
9
Original Article Detection of IL-2, IFN-γ, and serum-specific antibodies in the serum of children with atopic dermatitis
... (IL-2), interferon-γ (IFN-γ), and serum-specific antibodies in children with atopic dermatitis ...and IFN-γ in the ...and IFN-γ were compared between the two ...of ...
6
Incubation of Whole Blood at 39°C Augments Gamma Interferon (IFN-γ)-Induced Protein 10 and IFN-γ Responses to Mycobacterium tuberculosis Antigens
... e.g., IFN- ␥ , tumor ne- crosis factor alpha, IL-1, and IL-2, has been found to increase with incubation at fever-range temperatures, while the produc- tion of others, mainly Th2-specific cytokines such as IL-10, ...
7
Diagnostic value of pleural fluid interferon-gamma and adenosine deaminase in patients with pleural tuberculosis in Qatar
... fluid IFN- γ value, ADA activity, the histo- pathological and microbiological results of pleural biopsy, the etiology of the pleural effusion and duration of specific treatment, and ...
6
Susceptibility to Engineered Nanomaterial-Induced Toxicity in Mouse Models of Allergic Lung Disease.
... activation by assessing CD69 + cells by flow cytometry; in particular, alveolar macrophages and dendritic cells were found to have increased activation in silica NP/OVA treated mice compared to OVA alone [39]. Other ...
128
STAT1 modification improves therapeutic effects of interferons on lung cancer cells
... The IFN/STAT1 pathway is a typical signaling pathway that mediates crosstalk between tumor cells and compo- nents of the host microenvironment [7, ...8]. IFN activities rely on signaling through three types ...
10
Combining surgery and immunotherapy: turning an immunosuppressive effect into a therapeutic opportunity
... combinant IFN-α [52] and IL-2 [53–56] have demon- strated less NK- and T-cell suppression and improved prognosis following surgery in patients undergoing colorectal cancer [56] and hepatic metastasis resection ...
11
Obstruction of extrahepatic bile ducts by lymphocytes is regulated by IFN γ in experimental biliary atresia
... that IFN-γ plays a key regulatory role in the pathogenesis of bile duct injury and obstruction in biliary ...of IFN-γ expression completely prevented the inflammatory and fibrosing obstruction ...
9