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IgA nephropathy (IgAN)

Urinary miRNA profile for the diagnosis of IgA nephropathy

Urinary miRNA profile for the diagnosis of IgA nephropathy

... of IgA nephropathy, we did not explore – and there may not be any – biological role of the miRNAs that we ...with IgA vasculitis, so that a risk stratification based on urinary miRNA level is not ...

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Circulating immune complexes in IgA nephropathy consist of IgA1 with galactose deficient hinge region and antiglycan antibodies

Circulating immune complexes in IgA nephropathy consist of IgA1 with galactose deficient hinge region and antiglycan antibodies

... with IgA nephropathy (IgAN) consist of undergalactosylated, mostly polymeric, and J chain–containing IgA1 and IgG antibodies specific for N-acetylgalactosamine (GalNAc) residues in O-linked glycans ...

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Original Article Concurrent membranous nephropathy and IgA nephropathy: a series of 55 cases

Original Article Concurrent membranous nephropathy and IgA nephropathy: a series of 55 cases

... Membranous nephropathy (MN) accounts for ...logically. IgA nephropathy (IgAN) is the most common form of glomerulonephritis, account- ing for ...[1]. IgAN is characterized by variable ...

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Pathogenic role of (S)IgA in IgA nephropathy

Pathogenic role of (S)IgA in IgA nephropathy

... IgA nephropathy (IgAN) is characterized by mesangial deposition of polymer- ic IgA1 and ...secretory IgA. IgAN is associated with abnormal- ities in circulating IgA, including ...

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Mesangial cells from patients with IgA nephropathy have increased susceptibility to galactose-deficient IgA1

Mesangial cells from patients with IgA nephropathy have increased susceptibility to galactose-deficient IgA1

... with IgA deposits as well as their response to stimulation with ...with IgA nephropathy (IgAN) and controls were stimulated with IgA1 purified from blood from healthy controls (cIgA) or ...

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The genetics and immunobiology of IgA nephropathy

The genetics and immunobiology of IgA nephropathy

... IgA nephropathy (IgAN) represents a common form of primary glo- merulonephritis characterized by highly heterogeneous clinical and pathological features ...of IgAN relies entirely on a ...

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Association of high body mass index with development of interstitial fibrosis in patients with IgA nephropathy

Association of high body mass index with development of interstitial fibrosis in patients with IgA nephropathy

... and IgA nephropathy ...in IgAN. Berthoux et al. [12, 13] thought that IgAN pa- tients with high BMI had worse clinical outcome, al- though BMI did not show a direct effect on worse clinical ...

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Systemic Sarcoidosis Associated to IgA Nephropathy

Systemic Sarcoidosis Associated to IgA Nephropathy

... treatment. IgA nephropathy associated to atypical extrathoracic signs of sarcoidosis can induce lateness in sarcoidosis diagnostic delay; leading to pulmo- nary fibrosis, myocarditis, severe neurological ...

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Histopathological assessment of prognosis of IGA nephropathy.

Histopathological assessment of prognosis of IGA nephropathy.

... system is used for its simplicity and easy application in large multicentre studies. This scoring system as mild, moderate and severe is valuable in the analysis of a large clinical database. The weakness of the lumped ...

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IgA Nephropathy: A Malaysian Experience

IgA Nephropathy: A Malaysian Experience

... IgA Nephropathy A Malaysian Experience Med J Malaysia Vol 41 No 2 June 1986 IGA NEPHROPATHY A MALAYSIAN EXPERIENCE CHEONG I K s PHANG K s ABU BAKAR SULEIMAN ZAKIMORAD KONG B C T SUMMARY A total of 45[.] ...

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Immune regulation in IgA nephropathy

Immune regulation in IgA nephropathy

... systemic IgA [32] or IgA1 [30] immune response, also reported higher preimmunization levels in IgAN ...of IgA antibodies after immunization are related to these already elevated baseline levels, the ...

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A Study of mycophenolate and steroids in IGA nephropathy.

A Study of mycophenolate and steroids in IGA nephropathy.

... in IgAN [111]. More recent data suggest that IgA was co-deposited with MBL in about 25% of patients and that MBL deposition showed more severe renal disease as compared with MBL- negative cases, suggesting ...

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The coincidence of IgA nephropathy and Fabry disease

The coincidence of IgA nephropathy and Fabry disease

... We have reported a rare coincidence of two diseases IgAN and FD in two Czech patients. Only two case reports of the coincidence of IgAN and FD have been published in Caucasians [2,20]. The precise ...

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Role of Dendrtic Cells in IgA Nephropathy Pathogenesis

Role of Dendrtic Cells in IgA Nephropathy Pathogenesis

... In the research, it was discovered that the three groups of DCs highly express such surface markers as HLA-DR, CD83 and CDla but there is no significant difference (P>0.05) between the normal group and the IgAN ...

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Race/ethnicity and disease severity in IgA nephropathy

Race/ethnicity and disease severity in IgA nephropathy

... of IgAN received between November 1994 and May 2001 at the Renal Pathology Laboratory at UCSF were ...of IgAN superimposed on a systemic disease involving the kidney ...

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Efficacy and safety of immunosuppressive treatment in IgA nephropathy: a meta-analysis of randomized controlled trials

Efficacy and safety of immunosuppressive treatment in IgA nephropathy: a meta-analysis of randomized controlled trials

... for relieving proteinuria, and no additional sample size was required. In addition, immunosuppressants signifi- cantly decrease the risk for ESRD. Immunosuppressant therapy of IgAN has significant benefits. But it ...

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Time averaged albumin predicts the long term prognosis of IgA nephropathy patients who achieved remission

Time averaged albumin predicts the long term prognosis of IgA nephropathy patients who achieved remission

... with IgAN have been published [4,5,16,26,27], few studies have calculated the long-term renal outcomes of Chinese patients, especially those patients who achieve remission after ...in IgAN patients in the ...

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TWEAK/Fn14 system and crescent formation in IgA nephropathy

TWEAK/Fn14 system and crescent formation in IgA nephropathy

... with IgAN and other renal diseases were significantly higher than in the healthy controls ( P < ...the IgAN patients, the levels of uTWEAK correlated significantly with urinary protein excretion and ...

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The effect of model selection on cost-effectiveness research: a comparison of kidney function-based microsimulation and disease grade-based microsimulation in chronic kidney disease modeling

The effect of model selection on cost-effectiveness research: a comparison of kidney function-based microsimulation and disease grade-based microsimulation in chronic kidney disease modeling

... We compared MSM-dg and MSM-kf to evaluate the dif- ferences in the calculation results. In this study, we set MSM-kf as reference model, considering its potential to reflect the reality more than MSM-dg. As base case ...

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Title: miR-148b differentiates Tubular atrophy/Interstitial fibrosis histopathological stages in IgA

Title: miR-148b differentiates Tubular atrophy/Interstitial fibrosis histopathological stages in IgA

... time IgAN is diagnosed. The characteristics of IgAN and kidney biopsy practice seemed to be different in different parts of the world and it is not yet clear that it is the same disease ...The IgA ...

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