immature DCs
Infectious and Whole Inactivated Simian Immunodeficiency Viruses Interact Similarly with Primate Dendritic Cells (DCs): Differential Intracellular Fate of Virions in Mature and Immature DCs
... While immature DCs are susceptible to low-level productive infection with R5 HIV-1 strains, viral replication cannot be achieved in mature ...But immature and mature DCs are able to trap and ...
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Critical role of the Toll like receptor signal adaptor protein MyD88 in acute allograft rejection
... and immature DCs in the draining lymph nodes of allografts during the first 2 weeks after transplantation, and with impaired generation of antigraft T ...
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Original Article Distribution and expression profiles of dendritic cell subpopulations in human bladder cancer
... II molecules and integrin CD11c on their cell surface. Immature DCs express CD1a, adhe- sion molecules (such as CD209), and low level of HLA class II. After antigen uptake and pro- cessing, mDCs undergo ...
8
Williamson_unc_0153M_17858.pdf
... the DCs in regulating innate immunity in the neighboring ...cavity, DCs form a barrier of defense against constant microbial ...environment, immature DCs in the oral epithelial tissue migrated ...
60
Glycosphingolipid Composition of Human Immunodeficiency Virus Type 1 (HIV-1) Particles Is a Crucial Determinant for Dendritic Cell-Mediated HIV-1 trans-Infection
... by immature and mature DCs can localize within tetraspanin-positive endosomal compartments (20, 36, 73) or deep membrane invaginations, suggested to be contig- uous with the cell surface (79), which upon ...
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MyD88-dependent pro-interleukin-1β induction in dendritic cells exposed to food-grade synthetic amorphous silica
... inflammatory DCs derived from blood or bone marrow cultures stimu- lated with granulocyte-macrophage colony-stimulating factor (GM-CSF) [9, ...inflammatory DCs differ from the Flt3L-derived immature ...
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Dendritic Cells from Chronic Lymphocytic Leukemia Patients Are Normal Regardless of Ig V Gene Mutation Status
... that DCs generated from these patients did not differ in their ability to induce an in vitro recall response to TT when compared with ...generated DCs and TT-specific T cells from this group of patients are ...
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An immunohistochemical study of CD83- and CD1a-positive dendritic cells in the decidua of women with recurrent spontaneous abortion
... [5]. DCs play an important role in the initiation and regulation of immune responses by regulating T cell-mediated immunity ...[6,7]. DCs also play an important role in inducing immune tolerance [8]. ...
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Developing DNA vaccines that call to dendritic cells
... on immature DCs, is able to recruit DCs to the site of inoculation in mice, resulting in enhanced cellular immune responses and increased antibody titers ...
5
The Role of Human T-Lymphotropic Virus Type 1 (HTLV-1)-Infected Dendritic Cells in the Development of HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis
... culture, immature DCs were pulsed with either live or heat (56°C, 30 min)-inactivated HTLV-1 ...of DCs was performed by addition of 10 ng of lipopolysaccharide (LPS) from Escherichia coli O111:B4 * ...
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CD40 Ligand-Dependent Activation of Cytotoxic T Lymphocytes by Adeno-Associated Virus Vectors In Vivo: Role of Immature Dendritic Cells
... of DCs in AAV gene transfer, immature and mature DCs were separately infected with AAV-lacZ, Ad-lacZ, AAV-lacZ plus wild-type Ad or PBS (mock infection) for 72 h and then subjected to anti-Gal MAb ...
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Unexpected impairment of TNF α induced maturation of human dendritic cells in vitro by IL 4
... Background: An efficient strategy for programing dendritic cells (DCs) for cancer immunotherapy is the optimiza‑ tion of their maturation so that they can efficiently stimulate cancer‑specific T cell responses. ...
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Marked Suppression of T Cells by a Benzothiophene Derivative in Patients with Human T-Lymphotropic Virus Type I-Associated Myelopathy/Tropical Spastic Paraparesis
... which DCs, CSMs, and autoreactive T cells play major roles in the induction and progression of disease (5, 33, ...into DCs (27, 29) that bear the phenotypic and functional charac- teristics of ...
7
Phenotypic and Functional Alterations of Dendritic Cells Induced by Human Herpesvirus 6 Infection
... of DCs may be promoted by the soluble factor(s) produced by HHV-6-infected immature DCs; that is, the culture supernatant of HHV-6-infected DCs, which was irradiated with UV light to ...
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IL 10 induces aberrant deletion of dendritic cells by natural killer cells in the context of HIV infection
... of DCs, which are responsible for initiating adaptive immune responses, we investigated whether IL-10 induces changes in DC phenotype and function in the context of HIV ...of immature and mature human ...
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Impaired Accessory Cell Function in a Human Dendritic Cell Line after Human Immunodeficiency Virus Infection
... become immature DCs by treatment with IL-4 and granulocyte-macrophage colony-stim- ulating factor for 7 days, followed by TNF- ␣ for 3 days to obtain mature ...Both immature and mature DCs ...
12
Differentiation, Maturation, and Survival of Dendritic Cells by Osteopontin Regulation
... between DCs and OPN has not been ...between DCs and OPN, which is an indispensable extracellular matrix component in early cellular immune ...monocyte-derived DCs synthesized OPN especially during ...
7
Canarypox Virus-Induced Maturation of Dendritic Cells Is Mediated by Apoptotic Cell Death and Tumor Necrosis Factor Alpha Secretion
... MCM-treated immature DCs did not interfere with MCM-induced maturation (data not ...necrotic DCs drove DC maturation, at least ...ALVAC-exposed DCs facilitates DC mat- ...ALVAC-pulsed ...
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Spatial organization of dendritic cells within tumor draining lymph nodes impacts clinical outcome in breast cancer patients
... of DCs, both in-vitro and in-vivo, noting functional proper- ties associated with cluster size and maturation levels ...of immature DCs, mature DCs, and T cells within breast cancer TDLNs and ...
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Dendritic cell–derived exosomes for cancer therapy
... IFN-γ–matured DCs (mDex) has been one such new approach, following discoveries that mDex can induce greater T cell stimulation than Dex derived from immature DCs (24, 31, ...
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