Immune Mediated
Guidelines for treatment of immune-mediated cerebellar ataxias
... Cerebellar type of Hashimoto’s encephalopathy (HE) has been diagnosed based on the following criteria, (1) ele- vated anti-thyroid antibodies and (2) responsiveness to corticosteroids [1, 6, 57–62]. A series of reports ...
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Repurposing Miltefosine for the Treatment of Immune-Mediated Disease?
... in immune-mediated diseases (Bäumer et ...innate immune system predisposes to an excessive response of the adaptive immune response to intestinal micro- biota (Marks et ...macrophage- ...
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Immune Mediated Hemoltyic Anemia Detection in Dogs
... ABSTRACT: Immune mediated haemolytic anemia (IMHA) is a common cause of anemia in dogs ,a condition in which the immune system destroys its own blood ...
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Regulating Immune Mediated Pathology In Cutaneous Leishmaniasis: Roles For Il-22 And Skin Microbiota
... Cutaneous leishmaniasis is a chronic disease characterized by ulcerating and disfiguring skin lesions. Infection with different species of Leishmania parasites is responsible for the initiation of this disease, yet most ...
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Immune Mediated Damage Completes the Parabola: Cryptococcus neoformans Pathogenesis Can Reflect the Outcome of a Weak or Strong Immune Response
... normal immune response. Here, the immune response fails to limit fungal growth, which results in host ...strong immune responses that produce host damage stemming from ...strong immune ...
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Cancer as an immune-mediated disease
... the immune system to effectively respond to tumor growth is now recognized, the role of the immune system in controlling tumor initiation and expansion as well as cancer progression has been controversial ...
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Immune mediated thrombocytopenia of malaria
... significant immune complex ...by immune mechanisms; specific IgG binds to platelet-bound malaria antigen through the Fab portion of the immunoglobulin ...
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Targeting tumor-resident mast cells for effective anti-melanoma immune responses
... developed immune-related adverse events (irAEs) in terms of best overall response and overall ...with immune-related enterocolitis had a significantly better overall response (Figure 1A; P = ...with ...
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The role of leptin in innate and adaptive immune responses
... humoral immune responses and are protec- ted from immune-mediated inflammation in various models, such as experimental colitis, T-cell mediated hepatitis, glomeru- lonephritis and experimental ...
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Prime-boost using separate oncolytic viruses in combination with checkpoint blockade improves anti-tumour therapy.
... The anti-tumor effects associated with oncolytic virus therapy are mediated significantly 29.. through immune-mediated mechanisms which depends both on the type of v[r] ...
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Mathematical models for lymphatic filariasis transmission and control: Challenges and prospects
... dictions. Estimates from a model based on analysis of data from a hospital trial showed that a single dose DEC (6 mg/kg) can reduce the mf-production of adult worms by 67% at 12 months post-treatment and 87% at 24 months ...
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Nonimmunoglobulin E-Mediated Immune Reactions to Foods
... In addition, fewer laboratory diagnostic tools exist for non–IgE-mediated disorders than for IgE-mediated reactions. Food patch testing has been studied for AD, EE, Heiner’s syndrome, and (recently) FPIES, ...
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Computational systems biology of oxLDL induced macrophage foam cell formation A multilayer regulatory network analysis of atherogenic process
... The gene ontology terms of down regulated genes shown that, positive regulation of immune response, B-cell mediated immunity, lymphocyte mediated immunity, acute immunity response etc., [r] ...
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<p>Comprehensive Analysis of PD-1 Gene Expression, Immune Characteristics and Prognostic Significance in 1396 Glioma Patients</p>
... rst immune checkpoint blocking antibody approved for the treatment of advanced melanoma by the United States Food and Drug Administration (FDA), thus opening a new era of anti- tumor ...
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Neutrophil mediated innate immune resistance to mycobacteria
... It has long been recognized that some individuals exposed to infectious TB resist developing positive TST for longer periods than their peers despite similar exposure levels (2), raising the possibility that the innate ...
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Rim Pathway Mediated Alterations in the Fungal Cell Wall Influence Immune Recognition and Inflammation
... Th1 immune response is essential for clearing ...Th1 immune response ...particular immune response to various levels of fungal chito- oligomer exposure can be both beneficial and detrimental to the ...
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Autoimmunity conferred by chs3 2D relies on CSA1, its adjacent TIR NB LRR encoding neighbour
... CHS3-mediated defense responses are completely dependent on EDS1-90 and SAG101. To map the SOC loci, the soc chs3-2D mutants (which were generated in the Columbia (Col-0) ecotype) were crossed with wild type ...
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Obesity alters the immune response to influenza virus infection : a mechanism for immune modulation
... the immune dysfunction? Once possibility was the high circulating leptin levels found in obese ...in immune cells during infection, indicating leptin signaling was impaired and may have mediated some ...
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Exosomes derived from cancerous and non-cancerous cells regulate the anti-tumor response in the tumor microenvironment
... the immune response lies in the dysregulation and dysfunction of immune ...the immune response by producing immunosuppressive factors, such as nitric oxide and reactive oxidative species, and a ...
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Vector Order Determines Protection against Pathogenic Simian Immunodeficiency Virus Infection in a Triple-Component Vaccine by Balancing CD4+ and CD8+ T-Cell Responses
... Based on these findings, we assessed the efficacy of the combination of Ad- and FWPV-vectored vaccines administered in reverse order by two different routes. We investigated two prime-boost regimens using SCIV for priming, ...
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