in silico analysis
Antioxidant Activity and In Silico Analysis of Centella asiatica and Indigofera aspalathoides in Psoriasis
... In silico analysis performed using patch dock server to support the in vitro analysis. Eighteen compounds found in the FSE extract, one of the compound Dodecanoic acid,10 methyl- ,methyl ester, a ...
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Evolutionary and in silico analysis of the antiviral TRIM22 gene
... in silico computational methods were used to identify nsSNPs that are deleterious to TRIM22 structure and/or ...in silico prediction algorithms and evolutionary conservation data from the ConSurf web ...in ...
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Phenotype prediction for mucopolysaccharidosis type I by in silico analysis
... in silico analysis of coding region SNPs and UTR SNPs, ...in silico analysis is not sensitive enough for phenotype severity prediction because there are no algorithms specifically designed for ...
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In Silico Analysis of the Protein Structure of Tumor Suppressor Genes in Humans
... In silico analysis of the protein structures of Rb, p53, BRAC1 and BRAC2 genes revealed a high percentage of α-Helix content of the secondary protein structures of the genes; which provides maximal hydrogen ...
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In Silico Analysis of a MRP Transporter Gene Reveals Its Possible Role in Anthocyanins or Flavonoids Transport in Oryze sativa
... In silico analysis, the OsMRP15 (LOC_Os06g06440), an orthologous gene of mazie antho- cyanin transporter ZmMRP3, has been identified in ...phylogenetic analysis of MRPs in rice, mazie and Arabidopsis ...
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In silico analysis of the grapefruit sRNAome, transcriptome and gene regulation in response to CTV CDVd co infection
... Differential expression analysis was subsequently performed to identify transcripts involved in CTV- CDVd co-infection. In ‘Marsh’ and ‘Star Ruby’ 675 and 1204 transcripts, respectively, showed altered expression ...
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In silico analysis of the cyclophilin repertoire of apicomplexan parasites
... Phylogenetic analysis of the deduced FCBP domains does also not support a monophylic origin of alveolate FCBPs. Overall, phylogenetic distances between FKBP domains are much larger than for Cyp domains (compare ...
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IN SILICO ANALYSIS, MODELING, DOCKING AND PHARMACOPHORE STUDIES OF PROTEINS INVOLVED IN AUTO IMMUNE MALADIES (RHEUMATOID ARTHRITIS)
... i. RAMPAGE Server: Ramachandran Plot Analysis: A Ramachandran plot (also known as a Ramachandran diagram or a [φ,ψ] plot), originally developed in 1963 by G. N. Ramachandran, C. Ramakrishnan, and V. Sasisekharan, ...
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In silico analysis of histone H3 gene expression during human brain development
... in silico study, we re-evaluated genomic organization of the human H3 gene family and expression of these genes in the human brain, utilizing public RNA-based sequence datasets for the human genome and brain ...
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THE ADME/T PROFILES OF TB DRUGS – AN IN SILICO ANALYSIS
... Pharmacokinetics study is done by analyzing ADME and toxicity profile of the molecules. ADME (Absorption, Distribution, Metabolism and Excretion) properties are a set of physico- chemical and biochemical properties of ...
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IN-SILICO ANALYSIS OF ANDROGRAPHOLIDE AGAINST CANCER
... Molecular Docking: Graphical-Automatic Drug Design System for Docking, Screening and Post-Analysis program iGEMDOCK was used to gain the docking results of the listed compounds with the target. The binding site of ...
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In Silico Analysis on Docking Studies of Haemolysin Protein in Vibrio Paraheamolyticus
... (Structure analysis and verification server) and MolProbity (Structure - Validation server) that provides evaluation of mode quality in global and local arrangement of amino acids in Ramachandran plot for the ...
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<p>In silico Analysis, Molecular Docking, Molecular Dynamic, Cloning, Expression and Purification of Chimeric Protein in Colorectal Cancer Treatment</p>
... mRNA had enough stability to translate in the host effectively. Subsequently, higher stability brings about a higher expression rate. The mRNA structure was adjusted based on low Δ G and energy of the start codon. This ...
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Synthesis and in Silico Analysis of Novel 1,2,4-Triazolylamides as Potential Antifungals
... 0.1 M HNO 3 , 0.1 M HNO 3 , 0.1 M H 3 PO 4 , 1 M HClO 4 , 0.1 M HNO 3 +0.1 M NH 4 NO 3 it can be used for the quantitative analysis trace metal ion in environmental purpose. The results are shown in Table 7. ...
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Integrative analysis of neuroblastoma and pheochromocytoma genomics data
... Among the receptors involved in axonal guidance, the underexpression of NTRK1 (TrkA) was the most com- mon (observed in more than ten datasets) alteration in MYCN -amplifying and unfavorable NB (Figure 5). We have also ...
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The Role of Frontline Leadership in Organizational Learning: Evidence from Incremental Business Process Improvement
... role in diversifying protein function [20]. nsSNPs result in amino acid variations that may cause changes in protein stability. The physiochemical properties of the mutant residues differ from the wild type, resulting in ...
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Subgroup analysis reveals molecular heterogeneity and provides potential precise treatment for pancreatic cancers
... study, analysis of subgroup-specific clinical features was performed, and significant statistical differences in sex distribution, drinking history, tumor grade and diameter, and treatment response were ...in ...
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The alternative sigma factor SigF is a key player in the control of secretion mechanisms in Synechocystis sp. PCC 6803.
... proteomic analysis and the in silico search for SigF binding sites, confirmed the pleiotropic role of this sigma factor and a list of 12 gene candidates to be regulated by SigF emerged for further studies ...
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X Linked Dominant Congenital Ptosis Cosegregating with an Interstitial Insertion of a Chromosome 1p21 3 Fragment into a Quasipalindromic Sequence in Xq27 1
... in silico search for homologous sequences common to the critical region of chromosome Xq (as defined by FISH) and the dupli- cated fragment of the DPYD gene near the breakpoint areas as defined by array ...in ...
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Molecular Identification of Cryptococcus neoformans Serotypes
... PCR-REA is an easy-to-use approach and requires only common molecular materials. Its value for distinguishing among fungal species such as Malassezia spp. has already been emphasized (6). As restriction sites were chosen ...
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