in-vivo tissue characterization
In vitro characterization and in vivo evaluation of nanostructured lipid curcumin carriers for intragastric administration
... The mean concentration-time curve (AUC) and cor- responding pharmacokinetic parameters for curcumin and CUR-NLCs in rat organs for the two formulations are shown in Figure 5 and Table 3. After intragastric ...
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FORMULATION, CHARACTERIZATION AND IN-VIVO ASSESSMENT OF TOPICAL NANOEMULSION OF BETAMETHASONE VALERATE FOR PSORIASIS AND DERMATOSE
... Vaseline according to the protocol described by authors. [38-40] Animals were divided into four groups (n = 8). After tricotomization, all groups received sensitization with nickel sulfate in the abdomen, except the ...
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Tailored nanostructured platforms for boosting transcorneal permeation: Box–Behnken statistical optimization, comprehensive in vitro, ex vivo and in vivo characterization
... corneal tissue treated by normal saline solu- tion was considered as a negative control and is demonstrated in Figure 9A with normal stratified epithelium and stromal ...
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Evaluation of catheter-induced tribological damage to porcine aorta using infra-red spectroscopy
... for tissue damage characterization was conducted in two parts, a qualitative exploration of the ability of ATR-FTIR to discriminate between clearly damaged and undamaged tissue, followed by an ...
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Preparation, characterization, in vivo pharmacokinetics, and biodistribution of polymeric micellar dimethoxycurcumin for tumor targeting
... Plasma DMC levels declined obviously in the first 0.33 hours, while a slow decrease was observed subsequently. In addition, plasma concentrations in the DMC-PM group were obviously higher than those in the control group ...
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Preparation, characterization, in vitro and in vivo anti-tumor effect of thalidomide nanoparticles on lung cancer
... Tumor tissue specimens were extracted from nude mice, cut into pieces, and immediately mixed with 1 mL of 0.25% trypsin/EDTA (1:1, v/v). The mixture was incubated at 37 ° C for 37 min and stirred once every 10 ...
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Characterization of in Vivo Nitrate Reductase Activity in Triticum Vulgare Seedlings
... leaf tissue. This also facilitated us to use either 100 or 200 mg leaf tissue interchangeably depending on the nature of the tissue (greening shoots ...leaf tissue) 20 ...
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Preparation, characterization, and in vivo pharmacokinetics of nanostructured lipid carriers loaded with oleanolic acid and gentiopicrin
... Hepatic tissue specimens (5 mm × 5 mm × 3 mm) were taken from the same parts of the liver in each group and fixed in 10% neutral formaldehyde ...The tissue specimens were then dehydrated in alcohol, ...
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Impact of source tissue and ex vivo expansion on the characterization of goat mesenchymal stem cells
... Goat ASCs were more competent at adipogenesis than BM-MSCs, as reported for other species [8,9]. This could be explained by intrinsic epigenetic differences that primes resident MSCs in different source tissues to ...
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In silico and in vivo characterization of cabralealactone, solasodin and salvadorin in a rat model: potential anti-inflammatory agents
... dodecyl sulfate (8.1%, 0.2 mL), acetic acid (20%, 1.5 mL), and thiobarbituric acid (0.8%, 1.5 mL) were mixed, fol- lowed by centrifugation (3,000 rpm for 10 min). The upper organic layer was aspirated, and the optical ...
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Characterization of the Fat Channel for Intra-Body Communication at R-Band Frequencies
... fat tissue as a microwave intra-body communication channel at R-band frequencies ...fat tissue has been designed and ...three-layer tissue for the phantom and the ex-vivo porcine ...
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Comparative evaluation of moxifloxacin MDR-TB drug; as microspheres with respect to pure drug in lung tissue
... The novelty of the current work is the development of microparticulate drug delivery system solely through the judicious selection of apt blend of poly(lactic-co-glycolic acid)and emulsifier and validate by ...
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PREPARATION, CHARACTERIZATION AND IN VITRO - IN VIVO EVALUATION OF GLICLAZIDE LOADED POLYMERIC MICROSPHERES
... After checking those compatibility parameter optimized two formulations was chosen for in vivo anti-diabetic study. Both the formulation of Ethocel and Methocel K15M and Ethocel and Eudragit-RSPO combination ...
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Characterization and in vivo evaluation of novel lipid–chlorambucil nanospheres prepared using a mixture of emulsifiers for parenteral administration
... curves fit a two-compartment model, with the parameters shown in Table 7. Statistical analysis of concentration–time curve (AUC), clearance, and steady-state apparent volume of distribution of CHL after infusion of the ...
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Micro-CT – a digital 3D microstructural voyage into scaffolds: a systematic review of the reported methods and results
... The studies that report a value for resolution need to show how they quantify the resolution whether it is the pixel size given by the scanner software or they quanti- fied it with calibrated thickness wires [162]. Given ...
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Dexamethasone-loaded Polymeric Nanoconstructs for Monitoring and Treating Inflammatory Bowel Disease
... in vivo therapeutic studies, a 7 day DSS-administration period is ...in vivo and ex vivo NIRF imaging of the abdominal area and colon; length of the colon; mouse body weight, immunofluorescence and ...
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Development of Proniosomal Gel: in-vitro, ex-vivo and in-vivo Characterization
... preparation. Proniosomal formulation (F1), consisting of sodium cholate (concentration 3%) and cosolvent (isopropanol) attained highest penetrability effect, where sodium cholate and isopropanol induced significant ...
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Advances in the design of macroporous polymer scaffolds for potential applications in dentistry
... and tissue grafts to a tissue engi- neering approach that uses degradable porous three-dimensional (3D) material hydrogels integrated with cells and bioactive factors to regenerate tissues such as dental ...
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PREPARATION, CHARACTERIZATION AND IN VIVO RELEASE OF NANOMEDICINE (SOLID LIPID NANOPARTICLE) ASSOCIATE WITH THE EXTRACT OF PTEROSPERMUM ACERIFOLIUM FOR THE SCREENING OF NEUROBEHAVIOURAL
... PREPARATION, CHARACTERIZATION AND IN-VIVO RELEASE OF NANOMEDICINE SOLID LIPID NANOPARTICLE ASSOCIATE WITH THE EXTRACT OF PTEROSPERMUM ACERIFOLIUM FOR THE SCREENING OF NEUROBEHAVIOURAL An[r] ...
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Preparation and in vitro and in vivo characterization of cyclosporin A-loaded, PEGylated chitosan-modified, lipid-based nanoparticles
... in vivo results showed the biological half-life of the elimination phase (t 1/2β ) of the nanoparticles was 21 times longer than that of the cyclosporin A solution, and the area under the curve for the ...
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