Infected Hepatocytes
Apoptosis of Hepatitis B Virus-Infected Hepatocytes Prevents Release of Infectious Virus
... of infected cells is critically involved in antiviral ...of infected hepatocytes is required to combat hepatitis B virus (HBV) infection, it is still unknown which consequences hepatocyte apoptosis ...
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Envelope Protein-Mediated Down-Regulation of Hepatitis B Virus Receptor in Infected Hepatocytes
... in infected cultured hepatocytes; (ii) results from metabolic labeling experiments indicate enhanced receptor protein turnover; (iii) the kinetics of receptor loss from newly infected cells ...
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Promotion of Cancer Stem-Like Cell Properties in Hepatitis C Virus-Infected Hepatocytes
... HCV-infected hepatocytes displaying EMT generate CSC, we performed a sphere-forming assay to as- sess the capacity of self-renewal under ultralow binding culture ...mock- infected control ...
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Vol 2017
... target hepatocytes, infected hepatocytes and the virus, and it was used to approximate the rates of viral clearance and loss of infected hepatocytes by fitting to the model the decline ...
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Woodchuck Gamma Interferon Upregulates Major Histocompatibility Complex Class I Transcription but Is Unable To Deplete Woodchuck Hepatitis Virus Replication Intermediates and RNAs in Persistently Infected Woodchuck Primary Hepatocytes
... Gamma interferon (IFN-␥) plays an important role in host defense against infections and pathogenesis (reviewed in ref- erences 1 and 2). IFN-␥ shows various functions, e.g., activa- tion of macrophages and upregulation ...
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Fuzzy Logic Approach for Solving an Optimal Control Problem of an Uninfected Hepatitis B Virus Dynamics
... individual infected with the hepatitis B virus ...the infected hepatocytes, which lead to liver injury at the same time as clearing the virus from the ...
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Clonal Expansion of Normal-Appearing Human Hepatocytes during Chronic Hepatitis B Virus Infection
... of infected hepatocytes. Hepatocytes constitute a largely self-renewing ...of infected hepatocytes that occurs during the course of chronic ...>1,000 hepatocytes develop ...
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The Amount of Hepatocyte Turnover That Occurred during Resolution of Transient Hepadnavirus Infections Was Lower When Virus Replication Was Inhibited with Entecavir
... of infected hepatocytes per cycle was used in the simula- tions illustrated in Tables 2, 3, and 4; killing was assumed to be zero order ...of hepatocytes were killed during cycle 1, then the same ...
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Ribavirin Induces Error-Prone Replication of GB Virus B in Primary Tamarin Hepatocytes
... tamarin hepatocytes, we have previously developed a tissue culture system that exhibits high levels of GBV-B ...GBV-B-infected hepatocytes with ribavirin resulted in an approximately 4-log decrease ...
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Illegitimate replication of linear hepadnavirus DNA through nonhomologous recombination.
... mutant-infected hepatocytes (wt-5 and 66-1-18, ...We infected primary duck hepatocytes with the linear-DNA-containing viruses produced by transfection with these two plasmids and assayed for ...
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Molecular detection and quantification of Plasmodium falciparum infected human hepatocytes in chimeric immune deficient mice
... an infected humanized mouse ...visualize infected hepatocytes but quanti- fication and comparison of animals with different degrees of human hepatocyte repopulation remains diffi- ...
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Immune Suppression Uncovers Endogenous Cytopathic Effects of the Hepatitis B Virus
... have infected severe combined immune deficient mice (uPA-SCID), harboring human liver cells, with ...chimeras infected with HBV for more than 2 months showed that the majority of human hepatocytes ...
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Loss of nuclear PTEN in HCV-infected human hepatocytes
... HCV infected cells correlated with DSB, a hallmark of genomic ...HCV-infected hepatocytes showed increased γ-H2AX levels as compared to uninfected hepatocytes (Figure 6A, second lane from the ...
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Release of extracellular vesicles containing small RNAs from the eggs of Schistosoma japonicum
... SncRNAs carried by EVs function as messengers for intercellular communication. Therefore, we identified the small RNA populations associated with schistosomal egg EVs by Solexa deep sequencing. As shown in Fig. 2a, b, ...
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Parameters of Human Hepatitis Delta Virus Genome Replication: the Quantity, Quality, and Intracellular Distribution of Viral Proteins and RNA
... complexes that ␦RNA, with its negative charge, binds. In fact, 140 molecules of ␦Ag, each with a predicted charge of ⫹12 (21), would neutralize the charge of a unit-length ␦RNA molecule. This second model is supported by ...
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Regulation of herpes simplex virus γ134 5 expression and oncolysis of diffuse liver metastases by Myb34 5
... Humans represent the only species that is naturally infected by HSV-1. Both rodent and nonhuman pri- mate models for comparing the relative virulence of HSV-1 and HSV2 strains have been described (27–29, 43–47). ...
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Entry of Duck Hepatitis B Virus into Primary Duck Liver and Kidney Cells after Discovery of a Fusogenic Region within the Large Surface Protein
... Hepatitis B viruses exhibit a narrow host range specificity that is believed to be mediated by a domain of the large surface protein, designated L. For duck hepatitis B virus, it has been shown that the pre-S domain of L ...
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Hepatitis C Virus-Mediated Inhibition of Cathepsin S Increases Invariant-Chain Expression on Hepatocyte Surface
... rally infected human hepatocytes, preferentially stimulate CD8 ⫹ T cell ...in hepatocytes and dendritic cells ...expressing hepatocytes induce T helper 2 (Th2) cell differentiation of ...
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Cytokine gene expression in human hepatocytes infected with dengue virus serotype 3 (strain 16562)
... Viral RNA from D3V-infected C6/36 cell culture was isolated by using a PureLink Viral RNA/DNA Kit (Invi- trogen, CA) according to the manufacturer’s instructions, and viral RNA levels were quantified by real-time ...
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Infection Process of the Hepatitis B Virus Depends on the Presence of a Defined Sequence in the Pre-S1 Domain
... proteins. Hepatocytes were incubated with concentrated supernatants obtained from HepG2 cells transfected with L-defective genome complemented with different L expression vectors: NC, plasmid without an HBV insert ...
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