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Innate immune cells

The Fungal Quorum Sensing Molecule Farnesol Activates Innate Immune Cells but Suppresses Cellular Adaptive Immunity

The Fungal Quorum Sensing Molecule Farnesol Activates Innate Immune Cells but Suppresses Cellular Adaptive Immunity

... human innate immune ...host cells, we ex- amined the effects of FOH on viability of human monocytes, DC and PMN (17, ...protect cells against FOH induced cell death (24) (see ...these ...

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An evolving new paradigm: endothelial cells – conditional innate immune cells

An evolving new paradigm: endothelial cells – conditional innate immune cells

... functions. Cells of the immune system function to defend against invasive foreign pathogens and detrimental endogenous ...materials. Cells of the innate immune system cells in- ...

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Allergen recognition by innate immune cells: critical role of dendritic and epithelial cells

Allergen recognition by innate immune cells: critical role of dendritic and epithelial cells

... epithelial cells and recognize conserved microbial structures and as such play a key role in controlling adaptive immune ...radioresistant cells in the induction of TLR4-dependent Th2 responses to ...

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The role of innate immune cells in the pathogenesis of experimental autoimmune encephalomyelitis

The role of innate immune cells in the pathogenesis of experimental autoimmune encephalomyelitis

... "IFN-y-producing natural killer cells are pathogenic in experimental autoimmune encephalomyelitis by promoting Ml macrophage activation and VLA-4 expression on 004"^ T cells" - Internati[r] ...

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Pigment Nephropathy: Novel Insights into

Pigment Nephropathy: Novel Insights into

... Recent evidence suggests haem can trigger activation of innate immune cells via the NLRP3 216.. inflammasome.[r] ...

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Combination immunotherapy with TLR agonists and checkpoint inhibitors suppresses head and neck cancer

Combination immunotherapy with TLR agonists and checkpoint inhibitors suppresses head and neck cancer

... adaptive immune cells, we hypothesized that local treatment with TLR agonists, the innate immune activators, would improve antitumor efficacy by activating innate immune ...

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Endocytosis and human innate immunity

Endocytosis and human innate immunity

... attack. Innate immune cells play important roles in specifically recognizing and degrading microbes by generating phagosomes and ...how innate immunity regulates endocytosis in vitro and in ...

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Sexual Steroids and their Receptors Affect
Microglia-Mediated Neuroinflammation in
Neurodegenerative Diseases

Sexual Steroids and their Receptors Affect Microglia-Mediated Neuroinflammation in Neurodegenerative Diseases

... resident innate immune cells in the brain, has been long well-docu- mented to be decisive for maintaining the homeostasis of the ...its immune functions are associated with sexual ...

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There's Always Another Way! Cytomegalovirus’ Multifaceted Dissemination Schemes

There's Always Another Way! Cytomegalovirus’ Multifaceted Dissemination Schemes

... dissemination the innate immune cells must travel to the primary infection site and become infected 130.. and then leave this site.[r] ...

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Immune parameters, symptoms of upper respiratory tract infections, and training-load indicators in volleyball athletes

Immune parameters, symptoms of upper respiratory tract infections, and training-load indicators in volleyball athletes

... in innate immune cells (specifi- cally monocytes and neutrophils), and a decrease in adaptive immune cells (total lymphocytes) and higher incidence of upper respiratory tract infections ...

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High mammographic density in women is associated with protumor inflammation

High mammographic density in women is associated with protumor inflammation

... T cells and DC were integrated within the epithelium ...NK cells, B cells, and T cells in normal breast ...breast immune surveillance ...multiple immune cell types, especially ...

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Inflammation induced lymphangiogenesis 
in the cornea arises from 
CD11b positive macrophages

Inflammation induced lymphangiogenesis in the cornea arises from CD11b positive macrophages

... and/or innate immune cells were actively involved in the genesis of new lymphatic ...that innate immune cells (CD11b + macrophages, but not CD11c + dendritic cells) ...

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Review on Human Immune Response against Hepatitis B Virus (HBV) Infection

Review on Human Immune Response against Hepatitis B Virus (HBV) Infection

... (NK) cells and natural killer T-(NKT) cells are the first lines of defense, and the activation of these cells helps to reduce the viral load through the secretion cytokines, such as ...NKT ...

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Crosstalk between Innate Lymphoid Cells and Other Immune Cells in the Tumor Microenvironment

Crosstalk between Innate Lymphoid Cells and Other Immune Cells in the Tumor Microenvironment

... of cells, such as the ILC, is the necessity to define that subset with a range of different ...other cells of interest, the use of serial sections is required, labeling a certain cell type per section and ...

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Bacterial Pathogens Hijack the Innate Immune Response by Activation of the Reverse Transsulfuration Pathway

Bacterial Pathogens Hijack the Innate Immune Response by Activation of the Reverse Transsulfuration Pathway

... CTH-expressing cells, due to a lack of dcSAM, we also observed that putrescine accumulated in ...infected cells in the presence of AOAA or DZNeP, further demonstrating that induction of the RTP not only ...

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PubMedCentral-PMC5004954.pdf

PubMedCentral-PMC5004954.pdf

... KS is a disease of endothelial cells, and details of its pathobiology have been extensively reviewed. KS is among the most angiogenic cancers known to arise in humans. If we can decipher which factors drive KS and ...

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Regulation of autoreactive B cells during innate immune responses

Regulation of autoreactive B cells during innate immune responses

... the innate immune system is apparent in MRL/lpr mice (39). Immune complexes containing RNA or chromatin stimulate RF-specific B cells through TLR7 and TLR9 to secrete anti-Sm and ...

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Antiviral Innate Immune Response Interferes with the Formation of Replication Associated Membrane Structures Induced by a Positive Strand RNA Virus

Antiviral Innate Immune Response Interferes with the Formation of Replication Associated Membrane Structures Induced by a Positive Strand RNA Virus

... HuH-7-infected cells, whereas such structures were not observed in noninduced ...HA-nsp2-3GFP cells localized to the perinuclear region ...HuH-7/tetR/HA-nsp2-3GFP cells compared to that in ...

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Peripheral immune cell abnormalities associated with cystic fibrosis

Peripheral immune cell abnormalities associated with cystic fibrosis

... monocyte population. They express low levels of the chemokine receptors CCR2 and CCR5 but high levels of CX3CR1, which facilitates a prolonged patrolling behaviour along the endothelium that involves this population in ...

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Harnessing the immune system to treat cancer

Harnessing the immune system to treat cancer

... the immune system is to recognize and eliminate cells undergoing ...carcinogenesis. Immune defense against tumors is ...the innate immune system (i.e., phagocytes, NK cells, NKT ...

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