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inner ear

Axon guidance in the inner ear

Axon guidance in the inner ear

... the inner ear sensory organs where they will ultimately become post-synaptic to mature hair ...early ear development, neuroblasts delaminate from a restricted region of the ventral otocyst and ...

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Stem cells for the replacement of inner ear neurons and hair cells

Stem cells for the replacement of inner ear neurons and hair cells

... evidence was presented of neurite outgrowth toward hair cells from neural stem cells transplanted into the inner ear of guinea pigs (Hu et al., 2005b). However, the neurons of the host animal were not ...

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Pocket proteins and cell cycle regulation in inner ear development

Pocket proteins and cell cycle regulation in inner ear development

... the inner ear results in massive proliferation of HCs and to some extent SCs, followed by massive apoptotic death of all sensory HCs (Mantela et ...mitotic inner ear HCs may be difficult if ...

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Analysis of Netrin 1 receptors during inner ear development

Analysis of Netrin 1 receptors during inner ear development

... Fig. 2. Integrin subunits in the inner ear. RNA in situ hybridisation analysis of Itga3 (A,B), Itga6 (C,D) and Itgb1 (E,F) expression on sections from E12.0 (A-E) and E11.5 (F) mouse embryos. Arrows point ...

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Comparison of Inner Ear Contrast Enhancement among Patients with Unilateral Inner Ear Symptoms in MR Images Obtained 10 Minutes and 4 Hours after Gadolinium Injection

Comparison of Inner Ear Contrast Enhancement among Patients with Unilateral Inner Ear Symptoms in MR Images Obtained 10 Minutes and 4 Hours after Gadolinium Injection

... the inner ear structure was ...the inner ear structure and to diminish the measurement error, we determined every ROI twice for each patient on different days and averaged the signal ...

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Clinical and Radiologic Findings of Inner Ear Involvement in Sickle Cell Disease

Clinical and Radiologic Findings of Inner Ear Involvement in Sickle Cell Disease

... with inner ear symptoms may not have had any imaging evaluations and would not have been identi- fied on our initial imaging data base ...that inner ear abnormalities were present on routine ...

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Role of the hindbrain in dorsoventral but not anteroposterior axial specification of the inner ear

Role of the hindbrain in dorsoventral but not anteroposterior axial specification of the inner ear

... on inner ear ...the inner ear using the paint-fill technique ...Normal inner ear of controls at ...ventral inner ear structures in an ablated embryo ...The ...

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Fgf3 is required for dorsal patterning and morphogenesis of the
inner ear epithelium

Fgf3 is required for dorsal patterning and morphogenesis of the inner ear epithelium

... FGF signaling is also implicated in otic vesicle morphogenesis. FGF3 and FGF10 are expressed by prospective otic sensory tissues (Wilkinson et al., 1988; Mahmood et al., 1996; McKay et al., 1996; Pirvola et al., 2000; ...

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Human fetal inner ear involvement in congenital cytomegalovirus infection

Human fetal inner ear involvement in congenital cytomegalovirus infection

... The present study investigated the brain and the inner ear of 20 fetuses from women primarily infected by CMV be- fore 12 weeks gestation and with a positive prenatal diagno- sis. This study confirms the ...

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ASSESSMENT OF SUBCLINICAL INNER EAR DYSFUNCTION IN PSORIATIC ARTHRITIS PATIENTS

ASSESSMENT OF SUBCLINICAL INNER EAR DYSFUNCTION IN PSORIATIC ARTHRITIS PATIENTS

... Psoriatic arthritis (PsA) is a chronic inflammatory arthropathy of peripheral joints, spine and enthesis organs. It is characterized by various subtypes and variable clinical course and results usually by a chronic and ...

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Suppression of neural fate and control of inner ear morphogenesis by
Tbx1

Suppression of neural fate and control of inner ear morphogenesis by Tbx1

... The otocyst has been likened to the Drosophila imaginal disc (Fekete, 1996; Brigande et al., 2000). Both are transient embryonic structures derived by invagination of ectoderm and undergo extensive growth and ...

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The development of semicircular canals in the inner ear: role of FGFs in sensory cristae

The development of semicircular canals in the inner ear: role of FGFs in sensory cristae

... In the vertebrate inner ear, the ability to detect angular head movements lies in the three semicircular canals and their sensory tissues, the cristae. The molecular mechanisms underlying the formation of ...

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Limited inner ear morphogenesis and neurosensory development are possible in the absence of GATA3

Limited inner ear morphogenesis and neurosensory development are possible in the absence of GATA3

... (A,D) In both mutant and heterozygote embryos, FBM neurons have completed migration from rhombomere 4 to rhombomere 6 and the pres- ence of the SS nucleus in rhombomere 5 can clearly be seen in both. In the heterozygote ...

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Lack of Rbl1/p107 Effects on Cell Proliferation and Maturation in the Inner Ear

Lack of Rbl1/p107 Effects on Cell Proliferation and Maturation in the Inner Ear

... two inner ear structures and the inherent difficulty to manually dissect the sensory epi- ...the inner ear sensory epithelia (Tables 2 and ...

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Cell proliferation during the early compartmentalization of the Xenopus laevis inner ear

Cell proliferation during the early compartmentalization of the Xenopus laevis inner ear

... mammalian inner ear to regenerate damaged sensory cells in response to insult or injury due to terminal cell division during development is well characterized (Chardin et ...laevis inner ear ...

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Three dimensional MR of the inner ear with steady state free precession

Three dimensional MR of the inner ear with steady state free precession

... We have examined five patients with anom- alies in the development of the inner ear with both CT and MR. Among these cases, the most significant were one case of agenesis of the lateral semicircular canal, ...

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Mouse models to study inner ear development and hereditary hearing loss

Mouse models to study inner ear development and hereditary hearing loss

... the inner ear neuroepithelium will be ...the inner ear and its ...their inner ears, displayed more severely malformed inner ears and the neuroepithelium was completely absent, ...

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Biocompatibility of Liposome Nanocarriers in the Rat Inner Ear After Intratympanic Administration

Biocompatibility of Liposome Nanocarriers in the Rat Inner Ear After Intratympanic Administration

... the inner ear by anti-endothelial cell antibodies might play a role in causing the stria vascularis damage in immune- mediated sudden sensorineural deafness ...the inner ear, which might be ...

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Dual embryonic origin of the mammalian otic vesicle forming the inner ear

Dual embryonic origin of the mammalian otic vesicle forming the inner ear

... the inner ear Neurons and hair cells of the maculae derive from a common pool of neurosensory progenitors that express neurogenin 1 (Ngn1) (Raft et ...the inner ear and CVG coincide with the ...

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Macrophage migration inhibitory factor acts as a neurotrophin in the developing inner ear

Macrophage migration inhibitory factor acts as a neurotrophin in the developing inner ear

... Proteomic analyses demonstrate that MIF is present in the CM from both IMO and otocyst CMODF. It is also presumably released by the WT mouse OC, in contrast to the Mif KO OC (Fig. 6). Although IMO cell line or otocyst ...

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