INTEGRIN EXPRESSION
Breast cancer integrin expression and its relationship to tumour invasion and metastasis
... ltered integrin expression, how ever, was not related to vascular invasion in breast cancer (Table 4 ...the integrin subunits expressed in breast parenchym a recognised either o f these ...
302
Changes in integrin expression during keratinocyte terminal differentiation and immortalisation
... of integrin and E-cadherin from a diffuse apical cell surface distribution to cell-cell borders and a selective loss of Integrins from the terminally differentiating ...of integrin expression from ...
197
Alterated integrin expression in lichen planopilaris
... 7. Commo S, Bernard BA: The distribution of alpha 2 beta 1, alpha 3 beta 1 and alpha 6 beta 4 integrins identifies distinct sub- populations of basal keratinocytes in the outer root sheath of the human anagen hair ...
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Application of Molecular Ultrasound for Imaging Integrin Expression
... characterize integrin expression on ...where integrin targeted microbubbles were used to identify and characterize tumor angiogenesis and to assess tumor response to antiangiogenic drugs as well as ...
8
Age-related differences in integrin expression in peripheral blood lymphocytes
... Reduced expression of CD49d on T-cells, in particular as CD4+ and CD8+ sub-sets of CD3+ cells, in the older adults, indicates potentially impaired capability of T-cells to interact with HEVs and ...αβ ...
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Alterations in integrin expression modulates invasion of pancreatic cancer cells
... cancer, expression of integrins α6β1 [10-12] and αvβ3 [13] have previously been associated with invasion in cell lines and ...and integrin expression patterns makes it difficult to draw general ...
12
Integrin expression and function in osteoblasts
... The expression profile of integrin sub-units and heterodimers on the surface of both MG63 cells and HOBs was characterised using FACS ...specific integrin antibodies and FITC secondary ...the ...
190
Regulation of trophoblast beta1-integrin expression by contact with endothelial cells
... β1 integrin. Other data presented here suggest that increased expression of trophoblast β1 integrin is mediated by interaction of tro- phoblasts with endothelial cell platelet endothelial cell ...
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Integrin expression during epidermal morphogenesis and wound healing
... GRGDS (RGD: Arg-Gly-Asp) is the active site of the central cell-binding dom ain of fibronectin (H um phries 1990) and can thereby inhibit the function of several integrins. Peptides — due to their m uch sm aller size — ...
337
Endometrial beta3 Integrin profile reflects endometrial receptivity defects in women with unexplained recurrent pregnancy loss
... Methods: LH-timed endometrial biopsies were obtained from cases (RPL; n = 21, age 33.9+/ − 4.7) and healthy controls (n = 29; age 29.8+/ − 4.1) during the mid-secretory phase (post ovulatory day: 8 to 10). Endometrial ...
5
Integrins protect cardiomyocytes from ischemia/reperfusion injury
... but expression of integrins, includ- ing α7β1D, is increased, likely in compensation for loss of DGC components (40, ...increased integrin expression in protection of dystrophic skeletal muscle, we ...
16
PET Imaging of Integrin αVβ3 Expression
... of integrin expression is expected in the near fu- ...of integrin expression for patient se- lection and monitoring in the context of antiangio- genic or combined cytotoxic / antiangiogenic ...
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Stem cell fate in cultured human epidermis
... dermis, including the basem ent m embrane, on stem cell position, using the relative levels of integrin expression as a marker of stem cell patches. Integrin expression [r] ...
254
Human Adenovirus Type 37 Uses αVβ1 and α3β1 Integrins for Infection of Human Corneal Cells
... of integrin function in the life cycle of EKC-causing adenoviruses, we first investigated whether integrin expression on the human corneal epithelial (HCE) cell line matched the expression in ...
14
Study of expression of αvβ6 integrin in potentially malignant lesions: An Immunohistochemistry study
... receptor). Integrin α6β4 is an essential component of hemidesmosomes, which are adhesion structures on the basal surfaces of keratinocytes that anchor the epidermis to the dermis 59 ...down-regulate ...
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α5β1 integrin induces the expression of noncartilaginous procollagen gene expression in articular chondrocytes cultured in monolayers
... procollagen expression during dedifferentiation, siRNAs for respective AKT isoforms were introduced into primary cultured chondrocytes, and 3 days later expression of type I (COL1A1) (a) and type III ...
13
A small molecule induces integrin β4 nuclear translocation and apoptosis selectively in cancer cells with high expression of integrin β4
... We have been investigating the roles of ITGB4 in vascular endothelium cell (VEC) apoptosis. Increased ITGB4 level was accompanied by VEC apoptosis elicited by atorvastatin [9], deprivation of growth factors [10], safrole ...
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Integrin α1 subunit is up-regulated in colorectal cancer
... that integrin α1 subunit ex- pression is increased in a significant proportion of both tumoral and peri-tumoral colonic tissues, a phenomenon that appears to account for the strong expression of this ...
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Noncanonical roles of membranous lysyl-tRNA synthetase in transducing cell-substrate signaling for invasive dissemination of colon cancer spheroids in 3D collagen I gels
... paxillin expression levels. First, we established that c-Jun expression and Ser63 phosphorylation, but not Elk-1, p38, or JNKs expression and phosphorylation, were dependent on KRS expression ...
20
Interleukin-8 promotes integrin β3 upregulation and cell invasion through PI3K/Akt pathway in hepatocellular carcinoma
... follows: integrin αv 5′- CCAGGTGGTATGTGACCTTGGA-3′ (forward) and 5′-GCTGGTGCACACTGAAACGAA-3′ (reverse); integ- rin β3 5′-TTCAATGCCACCTGCCTCAA-3′ (forward) and 5′-TTGGCCTCAATGCTGAAGCTC-3′ (reverse); IL-8 ...
10