interferon-alpha
Interferon-alpha is a predisposing risk factor for carbamazepine-induced hyponatremia: A case of syndrome of inappropriate antidiuresis caused by interferon-alpha therapy
... that interferon therapy may have reinforced a direct or indirect pharmacological effect of other drugs on the renal ...Also, interferon therapy alone has not been demonstrated to cause ...and ...
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Improved Sustained Virological Response Following Treatment with Pegylated Interferon Alpha 2b Compared with Alpha 2a, Both with Ribavirin, for Chronic Hepatitis C Infection with Genotypes 2 and 3
... Pegylated Interferon Alpha-2b ver- sus Pegylated Interferon Alpha-2a, Both plus Ribavirin, to Treat Chronic Hepatitis C in Human Immunodefi- ciency virus Patients,” Hepatology, ...
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Synergistic inhibition of human cytomegalovirus replication by interferon alpha/beta and interferon gamma
... BioMed CentralVirology Journal ss Open AcceResearch Synergistic inhibition of human cytomegalovirus replication by interferon alpha/beta and interferon gamma Bruno Sainz Jr?, Heather L LaMarca?, Rober[.] ...
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Mechanisms of action of interferon-alpha in B-cell chronic lymphocytic leukaemia
... to interferon-alpha ...functions, interferon-alpha has the potential to alter the immune status of the patient and possibly to alter the course of the ...although ...
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Interaction of interferon alpha therapy with thyroid function tests in the management of hepatitis C: a case report
... inflammatory non-autoimmune thyroid dysfunction is clinically characterized by three phases, that is sudden onset of hyperthyroidism, followed by a hypothyroid state and eventually resolution and normalization of thy- ...
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Treatment of Hepatitis C with Pegylated Interferon Alpha 2a and Ribavirin: Experience from Benin
... DOI: 10.4236/ojgas.2018.88030 277 Open Journal of Gastroenterology CNHU-HKM in Cotonou. This was a cross-sectional study, retrospective from November 1, 2010 to December 31, 2015 (62 months) and prospective from January ...
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Deciphering the role of interferon alpha signaling and microenvironment crosstalk in inflammatory breast cancer
... an interferon response, STATs are ini- tially phosphorylated and IFNα signaling is initiated and re- solved quickly, but during chronic inflammation STATs lose their phosphorylation status even in the presence of ...
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Differential expression of interferon induced microRNAs in patients with chronic hepatitis C virus infection treated with pegylated interferon alpha
... [4]. Interferon (IFN) beta has been reported as modulating the expression of several cellular miRNAs that are capable of inhibiting hepatitis C virus (HCV) replication and infection, because they have ...
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Changes in peripheral blood lymphocytes in polycythemia vera and essential thrombocythemia patients treated with pegylated-interferon alpha and correlation with JAK2 V617F allelic burden
... high‑dose interferon Alfa‑2b versus cisplatin, vinblastine, and dacarbazine, plus interleukin‑2 and interferon in patients with high‑risk melanoma—an intergroup study of cancer and leukemia Group B, ...
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Human immune responses to Plasmodium falciparum infection: molecular evidence for a suboptimal THαβ and TH17 bias over ideal and effective traditional TH1 immune response
... alternate interferon alpha/ beta driven pathway ...feron alpha/beta and its related genes were found to be significantly up-regulated [25,26], thus providing further evidence at the gene level that ...
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Combining surgery and immunotherapy: turning an immunosuppressive effect into a therapeutic opportunity
... GM-CSF: Granulocyte macrophage colony stimulating factor; HSV: Herpes Simplex Virus; ICOS: Inducible T cell costimulator; IFN- α : Interferon alpha; IFN- γ : Interferon gamma; LPS/PHA: L[r] ...
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Classification, diagnosis, and management of conjunctival lymphoma
... Immunotherapy Interferon-alpha is a family of cytokines with anti-viral, anti-proliferative, and immunomodulatory ...sional interferon-alpha in the treatment of conjunctival lymphoma ...
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Influence of insulin resistance on the development of hepatocellular carcinoma after antiviral treatment for non-cirrhotic patients with chronic hepatitis C
... HCV: Hepatitis C virus; HCC: Hepatocellular carcinoma; PEG-IFN α : Pegylated interferon-alpha; SVR: Sustained virological response; AFP: Alpha-fetoprotein; HOMA-IR: Homeostasis model ass[r] ...
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Economic evaluation of pegylated interferon plus ribavirin for treatment of chronic hepatitis C in Thailand: genotype 1 and 6
... Methods: A cost-utility analysis using a model-based economic evaluation was conducted based on a societal perspective. A Markov model was developed to estimate costs and quality-adjusted life years (QALYs) comparing ...
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Study on the Presence of HCV RNA in PBMC as Compared with Plasma of Hepatitis C Patients after Treatment
... Also, 25 patients with HCV chronic infection which were positive for anti -HCV ELISA test and HCV- RNA RT-PCR in plasma were selected as positive control group. All patients were treated with Pegylated interferon ...
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Aqueous humour protein imbalances in primary open angle glaucoma and their effects on trabecular meshwork cell function
... Interferon alpha Interferon gamma Intraocular pressure Induced pluripotent stem cells Juxtacanalicular tissue Kilodalton Leukemia inhibitory factor Limb development membrane protein 1 li[r] ...
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Human Metapneumovirus M2-2 Protein Acts as a Negative Regulator of Alpha Interferon Production by Plasmacytoid Dendritic Cells
... ABSTRACT Human metapneumovirus (HMPV) has the ability to inhibit Toll-like re- ceptor 7 (TLR7)- and TLR9-dependent alpha interferon (IFN- ␣ ) production by plasma- cytoid dendritic cells (pDCs). However, ...
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The Pathogenesis of Severe Fever with Thrombocytopenia Syndrome Virus Infection in Alpha/Beta Interferon Knockout Mice: Insights into the Pathologic Mechanisms of a New Viral Hemorrhagic Fever
... However, alpha/beta interferon receptor knockout (IFNAR ⴚ/ⴚ ) mice were highly susceptible to SFTSV infection, and all mice died within 3 to 4 days after subcutaneous inoc- ulation of 10 6 focus-forming ...
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Quasispecies Heterogeneity within the E1/E2 Region as a Pretreatment Variable during Pegylated Interferon Therapy of Chronic Hepatitis C Virus Infection
... pegylated alpha-2a interferon plus ribavirin were studied for patterns of response to antiviral therapy and viral quasispecies ...NS5A interferon sensitivity deter- minant region were also analyzed ...
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Strain-Specific Differences in the Impact of Human TRIM5α, Different TRIM5α Alleles, and the Inhibition of Capsid-Cyclophilin A Interactions on the Infectivity of HIV-1
... with alpha interferon, expression of a pre-miRNA targeting TRIM5 ␣ , and/or overexpression of TRIM5 ␥ ), the inhibition of cyclophilin A (CypA)-CA interactions, and the expression of different allelic ...
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