interleukin-1β (6)
Urinary interleukin-1β levels among gynecological patients
... Lastly, obesity may increase tumor aggressiveness. In- creased metabolic activity and glucose concentrations driven by the Warburg effect [45] are associated with highly aggressive OC cell lines [46]. In cancer, the ...
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Differences in the Levels of Interleukin-1β (IL-1β) and Interleukin-1 Receptor Antagonist (IL-1ra) in Children with Status Epilepticus and Febrile Seizure
... 5. Johnston MV (2007) Seizures in childhood. In: Behrman RE, Kliegman RM, Jenson HB, eds. Nelson textbook of pediat- rics. 18th ed. WB Saunders Co., Philadelphia, pp 2457-2471. 6. Johnson EA, Kan RK (2010) The ...
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Primary Role of Interleukin-1α and Interleukin-1β in Lipopolysaccharide-Induced Hypoglycemia in Mice
... IL-1-deficient and control mice. Homozygous BALB/cA mice deficient in IL-1␣, IL-1, or both (IL-1␣ knockout [KO], IL-1 KO, and IL-1␣/ KO mice, respectively) were bred in our laboratory. These strains were originally ...
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Inhibition of Inflammasome Dependent Interleukin 1β Production by Streptococcal NAD+ Glycohydrolase: Evidence for Extracellular Activity
... During recent decades, life-threatening invasive GAS disease has increased globally, due in particular to emergence of a highly virulent M1T1 clone. Remarkably, invasive M1T1 strains isolated after 1988 seem to almost ...
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Tumor Necrosis Factor-α, Interleukin-1β, and Interleukin-6 Levels in Febrile, Young Children With and Without Occult Bacteremia
... Our controls were chosen from among the enrolled children who had negative blood cultures. In addi- tion we also required that the controls not have any other positive bacterial cultures or a chest radiograph consistent ...
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Midazolam suppresses interleukin-1β-induced interleukin-6 release from rat glial cells
... In the physiological CNS, IL-1 b , a pro-inflammatory cytokine, is expressed at low levels [11-13]. IL-1 plays a role in some physiological processes including sleep and synaptic plasticity [12]. Levels of IL-1 b ...
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... (TNF-α), interleukin-1β (IL-1β) and IL-6) with other factors (mid regional pro atrial natriuretic peptide [MR-proANP] and TNF-α) will cause left ventricular systolic dysfunction ...
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COMPARISON THE ANTIHYPERTENSIVE AND ANTIOXIDANT POTENTIAL BETWEEN YOUNG MAHOGANY SEEDS EXTRACT WITH MATURE MAHOGANY SEEDS EXTRACT IN RATS WITH HYPERTENSION
... of interleukin-8, matrix metalloproteinase, and interleukin-1β suggests a risk factor of a preterm labor for: 35 times (OR = ...is interleukin-8 (61%), followed by matrix metalloproteinase-8 ...
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Original Article Effect of acupuncture on expression levels of NF-κB, IL-1β, IL-6, and TNF-α in rats with cerebral ischemia and reperfusion
... (NF-κB), interleukin -1β (IL-1β), interleukin -6 (IL-6), and tumor necrosis factor-α (TNF-α) in rats with cerebral ischemia and ...
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An overview of curcumin in neurological disorders
... of interleukin-8 (IL-8), interleukin-1β (IL-1β) and TNF- α levels prompted us to observe its protective action in animal models of diabetic ...
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Proinflammatory MG 63 cells response infection with Enterococcus faecalis cps2 evaluated by the expression of TLR 2, IL 1β, and iNOS mRNA
... We further determined whether the capacity of the bac- terium tested in triggering osteoblast immune response took place through the regulation of certain innate immu- nity-related genes (TLR2, IL-1β, and iNOS). ...
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Sensing and Signaling in Antiviral Innate Immunity
... Viruses are detected by the innate immune system, leading to the initiation of the anti- viral immune response via the production of type I interferons and inflammatory cytokines such as interleukin-1. There has ...
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Original Article Effects of melatonin and 5-methoxytryptophol on synovial inflammation in the zymosan-induced rheumatoid arthritis in rats
... thogenesis of arthritis and causes an increase in the secretion of proteolytic enzymes such as matrix synovial metalopreoteinase-2 (MMP-2) and metalopreoteinase-9 (MMP-9) in stromal cells [5, 6]. These enzymes ...
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Erk1/2, CDK8, Src and Ck1e Mediate Evodia rutaecarpa Induced Hepatotoxicity in Mice
... Evodia rutaecarpa (E.R.) is a commonly used Chinese herbal medicine. However, it exerts certain hepatotoxicity and the underlying molecular mechanism has not been clarified. In this study, we investigated the molecular ...
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Differential expression of pro inflammatory cytokines IL 15Ralpha, IL 15, IL 6 and TNFalpha in synovial fluid from Rheumatoid arthritis patients
... cytokines interleukin 1 (IL1), tumour ne- crosis factor alpha (TNFalpha), and interleukin 6 (IL6), in particular, have been identified and intra-articular as well as systemic levels of these ...
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Glial contributions to neurodegeneration in tauopathies
... Neuroinflammation in tauopathies: Cause or effect? Gliosis and neuroinflammation are prevalent in tauopa- thy patient brains [4, 5, 106] and recapitulated across many animal models [127, 170–174]. Furthermore, ...
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Low density lipoprotein receptor–related protein 5 governs Wnt mediated osteoarthritic cartilage destruction
... LRP5 and LRP6 are paralogs that are 70% identical, and both are capable of stimulating the Wnt/β-catenin signaling pathway. Even though they have redundant and overlapping functions [28,29], several previous re- ports ...
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Prolonged mechanical ventilation–induced neuroinflammation affects postoperative memory dysfunction in surgical mice
... Despite considerable medical and economic burdens, delirium is poorly understood, and a lack of animal models has contributed to this. Therefore, the behavior assessment of cognitive decline in this study does not allow ...
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Coexpression and interaction of CXCL10 and CD26 in mesenchymal cells by synergising inflammatory cytokines: CXCL8 and CXCL10 are discriminative markers for autoimmune arthropathies
... Recombinant human IL-1β, TNF-α, IFN-γ and CXCL10 were purchased from PeproTech (Rocky Hill, NJ, USA). Recom- binant CXCL10(3–77) was generated by cleaving intact CXCL10 with CD26/DPP IV as previously described ...
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Abatacept blocks anti citrullinated protein antibody and rheumatoid factor mediated cytokine production in human macrophages in IDO dependent manner
... arthritis in mice and men [5–9, 28]. Furthermore, im- mune complexes have been shown to stimulate CD80 and CD86 expression, making monocyte lineage cells re- sponsive to abatacept [29]. Downregulation of several key ...
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