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Intermediate Filaments

Expression of intermediate filaments (IF) in tissues and cultured cells

Expression of intermediate filaments (IF) in tissues and cultured cells

... Int J DCL Biul n 55 tol (t989) 55 Expression of intermediate filaments (IF) in tissues and cultured cells ISMO VIRTANEW, KRISTIINA HEIKINHEIMO, MARKETTA HORMIA, TERO KIVELA LlISA lAITINEN and lARS ERI[.] ...

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Molecular manipulation of keratin 8/18 intermediate filaments: modulators of FAS- mediated death signaling in human ovarian granulosa tumor cells

Molecular manipulation of keratin 8/18 intermediate filaments: modulators of FAS- mediated death signaling in human ovarian granulosa tumor cells

... keratin filaments influence the traf- ficking of cytokine receptors, as demonstrated in the current study, is a relatively new and unique attribute ascribed to intermediate ...keratin filaments ...

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The roles and regulation of the actin cytoskeleton, intermediate filaments and microtubules in smooth muscle cell migration

The roles and regulation of the actin cytoskeleton, intermediate filaments and microtubules in smooth muscle cell migration

... the intermediate filament network, and microtubules; all of which regulate all or part of the migrated ...that intermediate filaments undergo reorganization during migration, which coordinates focal ...

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Adenovirus Triggers Reorganization of Vimentin-Containing Intermediate Filaments Resulting in the Perinuclear Movement of cPLA2 and Suppression of Prostaglandin Production

Adenovirus Triggers Reorganization of Vimentin-Containing Intermediate Filaments Resulting in the Perinuclear Movement of cPLA2 and Suppression of Prostaglandin Production

... C3HA cells are a well characterized murine 3T3-like fibroblast cell line that have been used extensively to study the effects of Ad on host cellular function (46, 48-50). Moreover, because these cells are murine in ...

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Beta, Beta'-Iminodipropionitrile-Induce Movement of Vimentin Intermediate Filaments to the Perinuclear Region is Insufficient to Inhibit cPLA2 Activity.

Beta, Beta'-Iminodipropionitrile-Induce Movement of Vimentin Intermediate Filaments to the Perinuclear Region is Insufficient to Inhibit cPLA2 Activity.

... other intermediate filaments, vimentin has an alpha-helical rod domain flanked by the two non-helical ...among intermediate filaments, while the rod domain varies considerably ...the ...

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Self consistent field theory for the interactions between keratin intermediate filaments

Self consistent field theory for the interactions between keratin intermediate filaments

... We have applied the SCF approach to study interactions of the unstructured N and C terminal domains of skin ker- atin (K1/K10) Intermediate Filaments. Positively charged N and C domains were grafted onto ...

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Intermediate filaments in malignant melanomas  Identification and use as marker in surgical pathology

Intermediate filaments in malignant melanomas Identification and use as marker in surgical pathology

... Intermediate-sized filaments have been studied in human malignant melanomas and in normal melanocytes by immunofluorescence microscopy with antibodies directed against keratin, vimentin, desmin, ...

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Functional expression of NF1 tumor suppressor protein: association with keratin intermediate filaments during the early development of human epidermis

Functional expression of NF1 tumor suppressor protein: association with keratin intermediate filaments during the early development of human epidermis

... keratin intermediate filaments during the forma- tion of desmosomes in cultured human ...and intermediate filaments during the formation of intercellular junctions in ...the ...

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Molecular manipulation of keratin 8/18 intermediate filaments: modulators of FAS-mediated death signaling in human ovarian granulosa tumor cells

Molecular manipulation of keratin 8/18 intermediate filaments: modulators of FAS-mediated death signaling in human ovarian granulosa tumor cells

... Current treatment of GCT entails surgical resection of the ovary and/or platinum-based chemotherapy - origin- ally developed to specifically eliminate ovarian surface epithelial (OSE) tumors [21]. However, ovarian ...

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Intermediate filaments of zebrafish retinal and optic nerve astrocytes and Müller glia: differential distribution of cytokeratin and GFAP

Intermediate filaments of zebrafish retinal and optic nerve astrocytes and Müller glia: differential distribution of cytokeratin and GFAP

... Background: Optic nerve regeneration (ONR) following injury is a model for central nervous system regeneration. In zebrafish, ONR is rapid - neurites cross the lesion and enter the optic tectum within 7 days; in mammals ...

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Estrous cycle-dependent changes of Fas expression in the bovine corpus luteum: influence of keratin 8/ 18 intermediate filaments and cytokines

Estrous cycle-dependent changes of Fas expression in the bovine corpus luteum: influence of keratin 8/ 18 intermediate filaments and cytokines

... specifically intermediate filaments, regulate expression of Fas on the surface of luteal cells, and hence lend spe- cificity to the process of Fas-induced apoptosis of luteal cells in the ...

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Estrous cycle-dependent changes of Fas expression in the bovine corpus luteum: influence of keratin 8/18 intermediate filaments and cytokines

Estrous cycle-dependent changes of Fas expression in the bovine corpus luteum: influence of keratin 8/18 intermediate filaments and cytokines

... specifically intermediate filaments, regulate expression of Fas on the surface of luteal cells, and hence lend spe- cificity to the process of Fas-induced apoptosis of luteal cells in the ...

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Intermediate filaments: primary determinants of cell architecture and plasticity

Intermediate filaments: primary determinants of cell architecture and plasticity

... Intermediate filaments (IFs) are major constituents of the cytoskeleton and nuclear boundary in animal cells. They are of prime importance for the functional organization of structural elements. Depending ...

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History and phylogeny of intermediate filaments: Now in insects

History and phylogeny of intermediate filaments: Now in insects

... As mentioned above, up to now it has been thought, because of the absence of cytoplasmic IF proteins from Drosophila melanogaster, that insects do not have cyto- plasmic intermediate filaments. This notion ...

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Introducing intermediate filaments: from discovery to disease

Introducing intermediate filaments: from discovery to disease

... form intermediate filaments (IFs) com- prise a unified protein family, the members of which are ubiquitous in virtually all differentiated cells and present both in the cytoplasm and in the ...

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Dysfunctions of neuronal and glial intermediate filaments in disease

Dysfunctions of neuronal and glial intermediate filaments in disease

... Intermediate filaments (IFs) are abundant structures found in most eukaryotic cells, including those in the ner- vous system. In the CNS, the primary components of neuronal IFs are α-internexin and the ...

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Immunoglobulin M autoantibody to vimentin intermediate filaments

Immunoglobulin M autoantibody to vimentin intermediate filaments

... of filaments was established as the 58,000-mol wt protein, vimentin: (a) the patient's serum reacts with a range of cell lines that contain intermediate filaments composed of vimentin, but not with ...

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Interaction of Theiler’s Virus with Intermediate Filaments of Infected Cells

Interaction of Theiler’s Virus with Intermediate Filaments of Infected Cells

... of intermediate filaments has recently been addressed by gene knockout ...that intermediate filaments are involved in cell resilience and maintenance of tissue integrity ...of ...

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Cultured human amniotic fluid cells characterized with antibodies against intermediate filaments in indirect immunofluorescence microscopy

Cultured human amniotic fluid cells characterized with antibodies against intermediate filaments in indirect immunofluorescence microscopy

... intermediate filament protein. E-1 cells did not show the typical cell-to-cell arrangement of keratin fibrils between the adjacent cells, a characteristic previously found in most cultured epithelial cells. Most ...

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IFN-γ-induced increase in the mobility of MHC class II compartments in astrocytes depends on intermediate filaments

IFN-γ-induced increase in the mobility of MHC class II compartments in astrocytes depends on intermediate filaments

... Fluorescent dextran labels MHC class II – positive late endosomes/lysosomes in WT and GFAP -/- Vim -/- astrocytes Before reaching the cell surface of APCs, MHC class II molecules are gen[r] ...

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