intervertebral disc degeneration
Lumbar intervertebral disc degeneration and related factors in Korean firefighters
... lumbar intervertebral disc level, indicating that the degree of lumbar intervertebral disc degeneration was higher in the fi eld group than in the administrative ...lumbar ...
6
Stem cell horizons in intervertebral disc degeneration
... Abstract: Intervertebral disc degeneration remains a pervasive and intractable disease arising from a combination of aging and stress on the back and ...the intervertebral disc, and the ...
10
Review Article Clarifying the nomenclature of intervertebral disc degeneration and displacement: from bench to bedside
... pain, intervertebral disc degeneration (IDD) has attracted more and more attention of both investigators and ...physicians. Disc herniation, termed as intervertebral disc ...
6
Biologic Treatment of Mild and Moderate Intervertebral Disc Degeneration
... Disc degeneration is the most common cause of back pain in adults and has enormous socioeconomic ...moderate disc degeneration, where a potential for regeneration still ...the ...
10
Intradiscal transplantation of synovial mesenchymal stem cells prevents intervertebral disc degeneration through suppression of matrix metalloproteinase related genes in nucleus pulposus cells in rabbits
... We next focused on the genes related to extracellular matrix, and the genes which possibly affect the extracellu- lar matrix. We found five genes related to collagen, six genes related to proteoglycan, three genes ...
13
Current strategies for treatment of intervertebral disc degeneration: substitution and regeneration possibilities
... Background: Intervertebral disc degeneration has an annual worldwide socioeconomic impact masked as low back pain of over 70 billion ...prolonged intervertebral disc mistreatment ...
19
In vivo experimental intervertebral disc degeneration induced by bleomycin in the rhesus monkey
... degenerative disc disease is the most common cause of low back ...generative disc disease have been introduced and devel- oped, including direct delivery of specific growth factors, plate-rich plasma, ...
10
Increased caveolin 1 in intervertebral disc degeneration facilitates repair
... The mammalian caveolin family consists of three pro- teins (caveolin-1, -2, and -3), which are integral mem- brane proteins essential for the structural integrity and function of caveolae (flask-shaped invaginations of ...
15
Regulation of catabolic gene expression in normal and degenerate human intervertebral disc cells: implications for the pathogenesis of intervertebral disc degeneration
... with degeneration, degen- erate IVDs show a much greater expression level of IL-1β than TNF-α and that, while the IL-1R1 was upregulated in degener- ation, the TNF receptor 1 (TNF-R1) was not ...
10
The role of interleukin 1 in the pathogenesis of human intervertebral disc degeneration
... of disc for the purposes of analysis – the NP, the Inner annulus fibrosus (IAF), and, where present, the outer annulus fibrosus (OAF) – and analysed ...for disc sections grouped with the scores 0 to 3, 4 to ...
15
The role of interleukin 1 in the pathogenesis of human Intervertebral disc degeneration
... of disc for the purposes of analysis – the NP, the Inner annulus fibrosus (IAF), and, where present, the outer annulus fibrosus (OAF) – and analysed ...for disc sections grouped with the scores 0 to 3, 4 to ...
14
Evaluation of canine intervertebral disc degeneration in colour-coded computed tomography
... IVD degeneration in CT ...IVD degeneration in non-contrast and colour-coded CT images were found by one ...IVD degeneration between Pfirrmann Grades 2 and 3 for the classification of IVD ...
7
Exosomes as potential alternatives to stem cell therapy for intervertebral disc degeneration: in-vitro study on exosomes in interaction of nucleus pulposus cells and bone marrow mesenchymal stem cells
... IVD degeneration have achieved great ...replenishing intervertebral disc cells via multipotent differentiation, promoting nucleus pulposus cell (NPC) proliferation, re- ducing apoptosis, resisting ...
11
Investigation of intervertebral disc degeneration using multivariate FTIR spectroscopic imaging
... of degeneration in comparison to the goat samples, two MCR-ALS PG signatures can be observed following the same trend; where the distribution/ tissue maps of PG1 (Factor 2, 1128 cm 1 ) show a lower presence in the ...
23
Accelerated cellular senescence in degenerate intervertebral discs: a possible role in the pathogenesis of intervertebral disc degeneration
... that disc cell senescence has an important role in the develop- ment and progression of IVD degeneration; thus, understand- ing the nature of cellular senescence will be paramount in devising new approaches ...
13
Accelerated cellular senescence in degenerate intervertebral discs: a possible role in the pathogenesis of intervertebral disc degeneration
... that disc cell senescence has an important role in the develop- ment and progression of IVD degeneration; thus, understand- ing the nature of cellular senescence will be paramount in devising new approaches ...
12
Expression of the RANK/RANKL/OPG system in the human intervertebral disc: implication for the pathogenesis of intervertebral disc degeneration
... To further identify the inhibitory effect of RANKL sig- naling on the expression of catabolic factors by human IVD cells, the activity of RANKL was next specifically neutralized by anti-human RANKL monoclonal antibody ...
13
Quantitative Molecular MRI of Intervertebral Disc Degeneration
... the disc were trimmed with a bone saw to include the endplate and approximately 1 cm of bony tissue, thus each disc specimen contained a single caudal disc sandwiched between vertebral endplates, ...
165
Serum lipid levels are positively correlated with lumbar disc herniation—a retrospective study of 790 Chinese patients
... lumbar disc degeneration (LDH) and High-TG or borderline High-LDL-C predicted a higher incidence of ...of intervertebral disc degeneration (IVDD) disease by controlling serum lipid ...
8
A Review of the Degenerative Intervertebral Disc Disease
... the degeneration, such as genetics, vascular aspects, mechanical stress, inflammatory and biochemical ...that intervertebral disc degeneration might be initiated by a long-lasting low-grade ...
6