Intervertebral disc degeneration (IDD)
Review Article Clarifying the nomenclature of intervertebral disc degeneration and displacement: from bench to bedside
... pain, intervertebral disc degeneration (IDD) has attracted more and more attention of both investigators and ...physicians. Disc herniation, termed as intervertebral disc ...
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Lumbar intervertebral disc degeneration and related factors in Korean firefighters
... lumbar intervertebral disc level, indicating that the degree of lumbar intervertebral disc degeneration was higher in the fi eld group than in the administrative ...lumbar ...
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Biologic Treatment of Mild and Moderate Intervertebral Disc Degeneration
... the intervertebral disc; the inner nucleus pulposus, the outer annulus fi- brosus and the cartilaginous end plate ...the disc and is composed of chondrocyte-like cells, water and a highly gelatinous ...
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Stem cell horizons in intervertebral disc degeneration
... Abstract: Intervertebral disc degeneration remains a pervasive and intractable disease arising from a combination of aging and stress on the back and ...the intervertebral disc, and the ...
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Comparison of MRI cross sectional area and functions of core muscles among asymptomatic individuals with and without lumbar intervertebral disc degeneration
... In previous studies [17–22], because participants were patients with LBP or symptomatic IDD of lumbar spine, pain could be responsible for the reduced CSA and core muscle functions [27]. The effect of pain on ...
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Increased caveolin 1 in intervertebral disc degeneration facilitates repair
... tebral disc (IVD) degeneration ...IVD degeneration, the glycosaminoglycan (GAG) and water content of the NP ...IVD degeneration with similar characteristics ...
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Evaluation of canine intervertebral disc degeneration in colour-coded computed tomography
... IVD degeneration in CT ...IVD degeneration in non-contrast and colour-coded CT images were found by one ...IVD degeneration between Pfirrmann Grades 2 and 3 for the classification of IVD ...
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The role of interleukin 1 in the pathogenesis of human Intervertebral disc degeneration
... of disc for the purposes of analysis – the NP, the Inner annulus fibrosus (IAF), and, where present, the outer annulus fibrosus (OAF) – and analysed ...for disc sections grouped with the scores 0 to 3, 4 to ...
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Expression of the RANK/RANKL/OPG system in the human intervertebral disc: implication for the pathogenesis of intervertebral disc degeneration
... IVD degeneration by interactions with the proinflammatory cyto- kines ...of disc degeneration by downregulating catabolic factors, including proinflammatory cytokines and matrix-degrading enzymes, ...
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The role of interleukin 1 in the pathogenesis of human intervertebral disc degeneration
... of disc for the purposes of analysis – the NP, the Inner annulus fibrosus (IAF), and, where present, the outer annulus fibrosus (OAF) – and analysed ...for disc sections grouped with the scores 0 to 3, 4 to ...
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Accelerated cellular senescence in degenerate intervertebral discs: a possible role in the pathogenesis of intervertebral disc degeneration
... that disc cell senescence has an important role in the develop- ment and progression of IVD degeneration; thus, understand- ing the nature of cellular senescence will be paramount in devising new approaches ...
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Regulation of catabolic gene expression in normal and degenerate human intervertebral disc cells: implications for the pathogenesis of intervertebral disc degeneration
... Our data demonstrate that TNF-α also upregulates IL-1 β and IL-1Ra genes, but not IL-1 α or IL-1R1, whereas IL-1β upreg- ulates TNF- α and TNF-R2. We have also previously shown that IL-1β upregulates itself and IL-1α ...
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Quantitative Molecular MRI of Intervertebral Disc Degeneration
... the intervertebral disc (IVD) is the most common cause of back-related disability among North American ...IVD degeneration, especially its biomolecular aspect, is poorly understood in an in vivo ...
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Inpatient gradual diagnostics and its relevance for determining treatment strategies in lumbar back pain
... Advanced intervertebral disc degeneration was observed between L5 and S1 (Pfirrmann grade 4) and a median intervertebral disc protrusion at ...joint degeneration was seen at L4/5 ...
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Landscape of RNAs in human lumbar disc degeneration
... Accumulating evidence indicates noncoding RNAs (ncRNAs) fine-tune gene expression with mysterious machinery. We conducted a combination of mRNA, miRNA, circRNA, LncRNA microarray analyses on 10 adults’ lumbar discs. ...
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Serum lipid levels are positively correlated with lumbar disc herniation—a retrospective study of 790 Chinese patients
... Lumbar disc herniation (LDH) is a major cause of low back pain and ...Lumbar disc abnormalities are frequently found in asymptomatic individuals by magnetic resonance im- aging ...of intervertebral ...
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Degenerative Disc Disease: A Review of Cell Technologies and Stem Cell Therapy
... to intervertebral disc ...for Intervertebral Disc (IVD) degeneration such as physical therapy and spinal fusion reduce symptoms' severity, but do not treat the source of ...treat ...
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Histological analysis of surgical lumbar intervertebral disc tissue provides evidence for an association between disc degeneration and increased body mass index
... excised disc material from a large orthopaedic spine center patient population (854 patients) that have been histopathologically evaluated by two histopathology units specialized in the evaluation of disc ...
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Radiological exploration on adjacent segments after total cervical disc replacement with Prodisc-C prosthesis
... Studies have shown that the incidence of ASD at 10-year follow up after ACDF, the classic procedure for the treat- ment of CDDD, is as high as 25–90% [10]. ASD was con- sidered to be linked with the loss of motion, the ...
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Intervertebral disc cells as competent phagocytes in vitro: implications for cell death in disc degeneration
... the intervertebral disc has been investigated by several groups, little attention has been paid to the subsequent physiological process and clearance of the apoptotic ...the disc were a vascularised ...
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